Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D. J. Philpott"'
Autor:
L. S. Tran, L. Ying, K. D’Costa, G. Wray-McCann, G. Kerr, L. Le, C. C. Allison, J. Ferrand, H. Chaudhry, J. Emery, A. De Paoli, N. Colon, S. Creed, M. Kaparakis-Liaskos, J. Como, J. K. Dowling, P. A. Johanesen, T. A. Kufer, J. S. Pedersen, A. Mansell, D. J. Philpott, K. D. Elgass, H. E. Abud, U. Nachbur, B. A. Croker, S. L. Masters, R. L. Ferrero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The interleukin-1 family members, IL-1β and IL-18, are processed into their biologically active forms by multi-protein complexes, known as inflammasomes. Although the inflammasome pathways that mediate IL-1β processing in myeloid cells hav
Externí odkaz:
https://doaj.org/article/818be30c523d402a9da4e7445e5bb564
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 6:23-23
Background Associations have been found linking certain LRRK2 kinase domain gain-of-function variants, such as G2019S, to the development of Crohn’s disease and Parkinson’s disease, yet their exact roles in pathogenesis remains elusive. LRRK2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::986256c2eae947b7d1b60413a082a6c7
https://doi.org/10.1093/jcag/gwac036.178
https://doi.org/10.1093/jcag/gwac036.178
Autor:
Oumaïma Ibrahim-Granet, J. P. Latgé, R. Athman, D. J. Philpott, L. Sengmanivong, M. Dubourdeau, B. Philippe, Viviane Balloy, Michel Chignard
Publikováno v:
Medical mycology. 44(Supplement_1)
Aspergillus fumigatus is a human pathogen, able to cause invasive aspergillosis in immunosuppressed patients. In the immunocompetent situation inhaled conidia are easily cleared by the immune system. Knowledge of the cellular pathways involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99440f354c0ee8f12cd4135c90e3da4b
https://pubmed.ncbi.nlm.nih.gov/30408906
https://pubmed.ncbi.nlm.nih.gov/30408906
Autor:
A, Goethel, W, Turpin, S, Rouquier, G, Zanello, S J, Robertson, C J, Streutker, D J, Philpott, K, Croitoru
Publikováno v:
Mucosal immunology. 12(3)
Inflammatory bowel disease (IBD) etiology involves genetic susceptibility, environmental triggers, and the gut microbiome. Antibiotic exposure is associated with IBD, both in early life and adulthood. Here, we investigated whether Nod2-deficiency inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0374927a91678250d022e35e3dc073f2
https://pubmed.ncbi.nlm.nih.gov/30858507
https://pubmed.ncbi.nlm.nih.gov/30858507
Publikováno v:
Alimentary Pharmacology & Therapeutics. 11:70-80
Research efforts in inflammatory bowel disease (IBD) have been directed towards the epithelium as it has become clear that epithelial cells play a critical role in inflammatory response. Most research involving IBD employs in vitro techniques. In vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc823a47a73f20321af0e0a3ee53a1f2
https://doi.org/10.1111/j.1365-2036.1997.tb00811.x
https://doi.org/10.1111/j.1365-2036.1997.tb00811.x
Autor:
Travassos, L. H, L. A. M. Carneiro, M. Ramjeet, S. Hussey, Y.-G. Kim, L. Yuan, F. Soares J. G. Magalhxe3es, L. LeBourhis, I.G. Boneca, A. Allaoui, N. L. Jones, G. Nuxf1ez, S. E. Girardi and D. J. Philpott, Travassos, L. H., L. A. M. Carneiro, M. Ramjeet, S. Hussey, Y.-G. Kim, L. Yuan, F. Soares J. G. Magalhxe3es, L. LeBourhis, I.G. Boneca, A. Allaoui, N. L. Jones, G. Nuxf1ez, S. E. Girardi, D. J. Philpott
Publikováno v:
Nature Immunol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=erc_________::22b7d2a87d878ad735cd4425cc460e4f
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 70:1201-1207
The small intestine is capable of adapting nutrient transport in response to numerous stimuli. This review examines several possible mechanisms involved in intestinal adaptation. In some cases, the enhancement of transport is nonspecific, that is, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188335a1c2ba6318d8346bda13d49112
https://doi.org/10.1139/y92-167
https://doi.org/10.1139/y92-167
Autor:
D. J. Philpott
Publikováno v:
Falk Symposium ISBN: 9781402028472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3935334753996ae570d31db40dda54e5
https://doi.org/10.1007/1-4020-2912-8_2
https://doi.org/10.1007/1-4020-2912-8_2
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 24:623-625
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c0ace49812aa025064455df34d8755
https://doi.org/10.1097/00005176-199705000-00026
https://doi.org/10.1097/00005176-199705000-00026
Publikováno v:
The Journal of infectious diseases. 172(1)
Attaching and effacing (AE) adhesion is associated with the pathogenesis of enteropathogenic Escherichia coli (EPEC) and rabbit diarrheogenic E. coli (RDEC-1). Although RDEC-1 provides an animal model for investigating pathophysiology of EPEC infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9169accf76ed726fc2da76ea755098ed
https://pubmed.ncbi.nlm.nih.gov/7541061
https://pubmed.ncbi.nlm.nih.gov/7541061