Výsledky vyhledávání - "D. J. Maudsley"

Infection of Cultured Murine Brain Cells by Semliki Forest Virus: Effects of Interferon- beta on Viral Replication, Viral Antigen Display, Major Histocompatibility Complex Antigen Display and Lysis by Cytotoxic T Lymphocytes

Autor: M. Blackman, P. T. Tomkins, A. Morris, D. J. Maudsley

Publikováno v: Journal of General Virology. 68:99-106

Primary brain cell cultures prepared from newborn mice were infected with Semliki Forest virus (SFV). The effects of interferon (IFN-alpha beta) treatment on SFV replication, SFV and major histocompatibility complex (MHC) class I antigen expression,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccfe2b4fc15796fe1ebe53b1fe415b8
https://doi.org/10.1099/0022-1317-68-1-99

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Kirsten murine sarcoma virus abolishes interferon gamma-induced class II but not class I major histocompatibility antigen expression in a murine fibroblast line

Autor: D J Maudsley, A G Morris

Publikováno v: The Journal of Experimental Medicine

The effect of infecting fibroblasts with Kirsten murine sarcoma virus/murine leukemia virus (Ki-MSV/MLV) on constitutive and IFN-gamma-induced H-2 antigen expression was investigated. The fibroblasts used were two established cell lines (C3H10T1/2 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e637a3c5407d572ddb3e6c0876650e15
http://europepmc.org/articles/PMC2188838

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A monoclonal antibody against antigen-specific helper factor augments T-cell help

Autor: R. F. L. James, Marc Feldmann, D. J. Maudsley, E. J. Culbert, Sirkka Kontiainen

Publikováno v: Nature. 301(5896)

Antigen-specific molecules, commonly termed ‘factors’, have been shown to be released from helper and suppressor T cells1,2. These factors mimic the activity of the cells that secrete them and there is much speculation about the relationship of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80920c5406b9d4be6aa882eb79a5d459
http://ora.ox.ac.uk/objects/uuid:d0e08266-1029-4107-a961-c277acae8cfa

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Rapid intracellular calcium changes in U937 monocyte cell line: transient increases in response to platelet-activating factor and chemotactic peptide but not interferon-gamma or lipopolysaccharide

Autor: D J, Maudsley, A G, Morris

Publikováno v: Immunology. 61(2)

The dye fura-2, a potentially more sensitive successor to quin2 for measuring intracellular free calcium ion concentrations [(Ca2+]i), has been applied here to investigate the possible involvement of early changes in [Ca2+]i in the stimulation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::343b0a0189109b07113f9ec31e528b22
https://pubmed.ncbi.nlm.nih.gov/3110054

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Monoclonal Antibodies Against Ia +, Antigen Specific T Cell Factors

Autor: E. J. Culbert, Marc Feldmann, D. J. Maudsley, Susan Edwards, R. F. L. James, Sirkka Kontiainen, Geoffrey H. Sunshine

We have produced a xenogeneic (rat) monoclonal antibody (AF3.44.4) against mouse T cell helper factors (HF's). This antibody will bind HF's of various strain and antigen specificities and therefore appears to recognise a ‘constant’ region. We rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32ea7af5a60845e3b07ec78ac47925dc
https://doi.org/10.1016/b978-0-08-029815-3.50108-2

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Regulation of IFN-gamma-induced host cell MHC antigen expression by Kirsten MSV and MLV. I. Effects on class I antigen expression

Autor: D J, Maudsley, A G, Morris

Publikováno v: Immunology. 67(1)

We have reported previously that the Kirsten murine sarcoma virus (Ki-MSV) that carries the v-Ki-ras oncogene prevents C3H10T 1/2 fibroblasts from being able to respond to interferon-gamma (IFN-gamma) with the expression of the class II major histoco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ff6dbfd2ccfcc1daad0691c99b70745
https://pubmed.ncbi.nlm.nih.gov/2544513

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Inhibition of expression of cell-mediated immunity by a cell surface-binding antibody directed against T-cell helper factors

Autor: L S, Anthony, R F, James, D J, Maudsley, P A, Kongshavn

Publikováno v: Immunology. 65(2)

In this study, the effects of a monoclonal antibody, AF3.44.4, which is directed against antigen-specific, T-cell-derived helper factors, were investigated in two models of T-cell-macrophage co-operation. In vitro, cultures of nylon-wool-enriched per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ba39da52405040154aa482a27bbabb5
https://pubmed.ncbi.nlm.nih.gov/3263944

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Monoclonal Antibodies to Antigen Specific Factors — A New Tool for their Analysis

Autor: Marc Feldmann, Sirkka Kontiainen, D. J. Maudsley, R. F. L. James, E. J. Culbert

Publikováno v: Ir Genes ISBN: 9781461256359

There is still much confusion about the heterogeneity of T cells and the mechanisms of their action in various immune responses. To some extent there are prospects for resolving these issues as there are much improved methods for analysing these prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41c35fa620bde52a6284c599c4c33f85
https://doi.org/10.1007/978-1-4612-5633-5_84

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