Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D. J. Law"'
Publikováno v:
Biochemical and Biophysical Research Communications. 262:113-120
Among transcription factors that regulate ornithine decarboxylase (ODC) gene expression are those that interact with GC-rich promoters, including Sp1 and ZBP-89. Sp1 functions as a transactivator and ZBP-89 as a transrepressor of both the ODC and gas
Autor:
A. J. Bale, D. J. Law
Publikováno v:
Geological Society, London, Special Publications. 139:57-68
Autor:
T. C. Gebuhr, Jonathan G. Seidman, Lynn B. Jorde, M. E. Moore, P. Franceschini, R C Lin, L. B. Holmes, R. Lala, P. A. Krakowiak, W C Watkins, D. J. Law, Christine E. Seidman, Michael J. Bamshad, Benoit G. Bruneau, A Schinzel
Publikováno v:
Nature Genetics. 16:311-315
Ulnar-mammary syndrome is a rare pleiotropic disorder affecting limb, apocrine gland, tooth and genital development. We demonstrate that mutations in human TBX3, a member of the T-box gene family, cause ulnar-mammary syndrome in two families. Each mu
Publikováno v:
Cell motility and the cytoskeleton. 45(3)
The regions of mouse nebulin extending from the ends of the super repeats to the C-terminus and N-terminus were cloned and sequenced. Comparison of the mouse sequence with the previously published human sequence shows that the terminal regions of neb
Publikováno v:
The Biochemical journal. 337
Heparan sulphate proteoglycans on cell surfaces have been shown to mediate the degradation or recycling of several ligands. Since the interaction with ligand may affect proteoglycan catabolism once the complex is internalized, this could alter the ce
Publikováno v:
Genes, chromosomescancer. 17(1)
Whole genome analyses of breast tumors with polymorphic markers have detected nonrandom loss of heterozygosity on multiple chromosomes, providing clues to the locations of suspected tumor suppressor genes. Tumors are thought to initiate, progress, an
Autor:
D J, Law, J G, Tidball
Publikováno v:
The American journal of pathology. 142(5)
The myotendinous junction (MTJ) is the major site of force transmission from myofibrils across the muscle cell membrane to the extracellular matrix. The MTJ is thus an appropriate model system in which to test the hypothesis that dystrophin, the gene
Autor:
M A, Maw, P E, Grundy, L J, Millow, M R, Eccles, R S, Dunn, P J, Smith, A P, Feinberg, D J, Law, M C, Paterson, P E, Telzerow
Publikováno v:
Cancer research. 52(11)
Loss of heterozygosity studies have been used to identify chromosomal regions which are frequently deleted and thus indicate areas which may harbor tumor suppressor genes. As a result, both the WT1 gene located in chromosome 11p13 and an unidentified
Publikováno v:
Journal of the Royal College of Surgeons of Edinburgh. 36(4)
A prospective survey of 1086 general surgical in-patients was carried out in West Dorset district to determine the incidence of postoperative infections for individual surgeons. A total of 79 cases were diagnosed as having become infected, resulting
Autor:
J G, Tidball, D J, Law
Publikováno v:
The American journal of pathology. 138(1)
Dystrophin, the deficient gene product in Duchenne muscular dystrophy, is located subjacent to the muscle cell membrane at myotendinous junctions, as well as along the entire muscle cell. Myotendinous junctions are sites at which thin filaments norma