Zobrazeno 1 - 10
of 44
pro vyhledávání: '"D. J. Buchsbaum"'
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74c70d0de7242b64a586f3086697f1e
https://doi.org/10.1002/chin.199416259
https://doi.org/10.1002/chin.199416259
Publikováno v:
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR). 44(3)
Utilization of molecular biology techniques offers attractive options in nuclear medicine for improving cancer imaging and therapy with radiolabeled peptides. Two of these options include utilization of phage-panning to identify novel tumor-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bee039342332728ef547804f4d95695
https://pubmed.ncbi.nlm.nih.gov/11105586
https://pubmed.ncbi.nlm.nih.gov/11105586
Autor:
F J, Kelly, C R, Miller, D J, Buchsbaum, J, Gomez-Navarro, M N, Barnes, R D, Alvarez, D T, Curiel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(11)
Efficient gene transfer by recombinant adenovirus (Ad) vectors depends on expression of CAR and alpha(v) integrin on target cells. Because Ad may also infect nearby nontarget cells expressing these receptors, such as peritoneal mesothelial cells afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7c8bbd586e716de3b24c3f725ece24d
https://pubmed.ncbi.nlm.nih.gov/11106250
https://pubmed.ncbi.nlm.nih.gov/11106250
Autor:
J A, Bonner, K P, Raisch, H Q, Trummell, F, Robert, R F, Meredith, S A, Spencer, D J, Buchsbaum, M N, Saleh, M A, Stackhouse, A F, LoBuglio, G E, Peters, W R, Carroll, H W, Waksal
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 18
Epidermal growth factor receptor (EGFr) is overexpressed in a majority of head and neck squamous cell carcinomas, and this overexpression is associated with a poor prognosis. Therefore, EGFr has become the target of investigations aimed at disabling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4efacde85e42cc7d21702fb3afcf44f3
https://pubmed.ncbi.nlm.nih.gov/11060327
https://pubmed.ncbi.nlm.nih.gov/11060327
Publikováno v:
Blood. 96(3)
Immunotoxin (IT) therapy shows potential for selectively eliminating GVHD-causing T cells in vivo, but the field has been hampered by toxicity. Previously, we showed that a genetically engineered IT consisting of a single-chain protein, including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93db98e926c30eb88475b67841541283
https://pubmed.ncbi.nlm.nih.gov/10910937
https://pubmed.ncbi.nlm.nih.gov/10910937
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(5)
Gene therapy protocols require better modalities to monitor the location and level of transferred gene expression. One potential in vivo mechanism to assess gene expression would be to image the binding of a radiolabeled peptide to a reporter recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf4d1e5df4a5bfa2b85b48541991a0b4
https://pubmed.ncbi.nlm.nih.gov/10809205
https://pubmed.ncbi.nlm.nih.gov/10809205
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
One of the problems in achieving cures with radioimmunotherapy is that hematological toxicity limits the quantity of radiolabeled monoclonal antibody (MAb) that can be administered. The MAb CC49 binds with high affinity to the TAG-72 antigen expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::632ccff3d9e155c21daee2aa04248bd8
https://pubmed.ncbi.nlm.nih.gov/10541357
https://pubmed.ncbi.nlm.nih.gov/10541357
Autor:
D J, Buchsbaum, B E, Rogers, M B, Khazaeli, M S, Mayo, D E, Milenic, S V, Kashmiri, C J, Anderson, L L, Chappell, M W, Brechbiel, D T, Curiel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Novel strategies to increase the therapeutic ratio in clinical radioimmunotherapy studies are needed. Limitations to radioimmunotherapy include bone marrow suppression due to the long circulating half-life of radiolabeled monoclonal antibodies (mAbs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27b351f7f8f74f5bed773a6b8347fe8e
https://pubmed.ncbi.nlm.nih.gov/10541342
https://pubmed.ncbi.nlm.nih.gov/10541342
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
The trihydroxamate bifunctional chelating agent (BCA), trisuccin, has been shown to be a potential ligand for radiolabeling of monoclonal antibodies (MAbs) with rhenium radioisotopes, through an indirect postconjugation approach. The use of this trih
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2028e1765694a6ca019fe84734235024
https://pubmed.ncbi.nlm.nih.gov/10541333
https://pubmed.ncbi.nlm.nih.gov/10541333
Autor:
B E, Rogers, S F, McLean, R L, Kirkman, D, Della Manna, S J, Bright, C C, Olsen, A D, Myracle, M S, Mayo, D T, Curiel, D J, Buchsbaum
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(2)
Adenoviral vectors, encoding genes for cell surface antigens or receptors, have been used to induce their high level expression on tumor cells in vitro and in vivo. These induced antigens and receptors can then be targeted with radiolabeled antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13673d6061b264929c56fcb6c13e69a3
https://pubmed.ncbi.nlm.nih.gov/10037188
https://pubmed.ncbi.nlm.nih.gov/10037188