Zobrazeno 1 - 10
of 620
pro vyhledávání: '"D. J. Benos"'
Publikováno v:
The Journal of Immunology. 156:1307-1314
It is well established that the two major glial cells in the central nervous system (CNS), astrocytes and microglia, are key participants in mediating the neurologic dysfunction associated with HIV infection of the CNS. In this study, we investigated
Publikováno v:
American Journal of Physiology-Cell Physiology. 266:C1105-C1111
The toad urinary bladder and epithelial cell lines derived from the urinary bladder, including TBM, serve as model systems for the study of transepithelial Na+ transport. We examined biochemical characteristics of epithelial Na+ channels in toad urin
Autor:
M. R. Sullivan, Subbarao V. Yalla, Michael Kashgarian, T. R. Kleyman, G. Otuechere, Mark L. Zeidel, Shang-Jyh Hwang, D. J. Benos, Hobart W. Harris
Publikováno v:
American Journal of Physiology-Renal Physiology. 264:F808-F815
Urinary obstruction markedly reduces collecting duct Na+ reabsorption. To define the cellular mechanisms of this derangement in Na+ reabsorption in inner medullary collecting duct (IMCD) of obstructed kidneys, suspensions of intact IMCD cells and inn
Autor:
Olivier Staub, Bernard C. Rossier, François Verrey, D J Benos, T R Kleyman, Jean-Pierre Kraehenbuhl
Publikováno v:
The Journal of Cell Biology
High resistance epithelia express on their apical side an amiloride-sensitive sodium channel that controls sodium reabsorption. A cDNA was found to encode a 1,420-amino acid long polypeptide with no signal sequence, a putative transmembrane segment,
Autor:
Douglas H. Robinson, D. J. Benos
Publikováno v:
Reproduction. 91:493-499
The metabolism of glucose in the intact Day-6 and -7 post coitum (p.c.) rabbit blastocyst and in the separated trophectoderm and inner cell mass (ICM) of the Day-7 p.c. embryo was investigated. At Day-6 p.c., glucose traversed the trophectoderm with
Autor:
D J Benos, David J. Randall, Jonathan M. Wilson, P Laurent, Bruce L. Tufts, Mark Donowitz, A.W. Vogl
Publikováno v:
The Journal of experimental biology. 203(Pt 15)
Teleost fishes, living in fresh water, engage in active ion uptake to maintain ion homeostasis. Current models for NaCl uptake involve Na(+) uptake via an apical amiloride-sensitive epithelial Na(+) channel (ENaC), energized by an apical vacuolar-typ
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 278(5)
Publikováno v:
The American journal of physiology. 275(5)
The hypothesis that amiloride-sensitive Na+ channels (ENaC) are involved in cell volume regulation was tested. Anisosmotic ND-20 media (ranging from 70 to 450 mosM) were used to superfuse Xenopus oocytes expressing alpha beta gamma-rat ENaC (alpha be
Publikováno v:
Biology of the cell. 89(4)
Intracellular pH has been shown to be an important physiological parameter in cell cycle control and differentiation, aspects that are central to the spermatogenic process. However, the pH regulatory mechanisms in spermatogenic cells have not been sy
Publikováno v:
The American journal of physiology. 272(4 Pt 1)
Atomic force microscopy (AFM) was used for high-resolution imaging of the apical distribution of epithelial Na+ channels in A6 renal epithelial cells. A6 cells grown on coverslips were labeled with antibodies generated against an amiloride-sensitive