Zobrazeno 1 - 10
of 1 162
pro vyhledávání: '"D. Irvine"'
Autor:
K. Cwynarski, E. Tholouli, G. Iacoboni, T. Menne, D. Irvine, L. Wood, N. Balasubramaniam, J. Shang, M Zhang, K. Duffy, B. Huber, M. Vinson, W. Brugger, M. Pule
Publikováno v:
HemaSphere, Vol 6, Pp 162-163 (2022)
Externí odkaz:
https://doaj.org/article/42d775561f2f463fb3c48acaa5443054
Autor:
C. Roddie, J. Dias, M. O’Reilly, M. Mitsikakou, E. Charalambous, L. Green, M. Vaughan, G. Agliardi, J. Garcia, E. Lewin, M. Lowdell, M. Marzolini, L. Wood, H. Holmes, Y. Ngai, B. Popova, W. Wilson, S. Kunaseelan, V. Spanswick, H. Lowe, L. Ensell, J. Hartley, S. Domning, S. Morley, T. Marafioti, A. Bloor, D. Irvine, K. Orchard, A. Khwaja, D. Linch, M. Pule, K. Peggs
Publikováno v:
HemaSphere, Vol 6, Pp 1341-1342 (2022)
Externí odkaz:
https://doaj.org/article/ccf3e17813454e38bf354af2e1572519
Publikováno v:
JID Innovations, Vol 4, Iss 3, Pp 100269- (2024)
Staphylococcus aureus (SA) colonizes and can damage skin in atopic dermatitis lesions, despite being commonly found with Staphylococcus epidermidis (SE), a commensal that can inhibit SA’s virulence and kill SA. In this study, we developed an in sil
Externí odkaz:
https://doaj.org/article/87626df07f69429482ded329375dd804
Autor:
Ashley Budu-Aggrey, Anna Kilanowski, Maria K. Sobczyk, andMe Research Team, Suyash S. Shringarpure, Ruth Mitchell, Kadri Reis, Anu Reigo, Estonian Biobank Research Team, Reedik Mägi, Mari Nelis, Nao Tanaka, Ben M. Brumpton, Laurent F. Thomas, Pol Sole-Navais, Christopher Flatley, Antonio Espuela-Ortiz, Esther Herrera-Luis, Jesus V. T. Lominchar, Jette Bork-Jensen, Ingo Marenholz, Aleix Arnau-Soler, Ayoung Jeong, Katherine A. Fawcett, Hansjorg Baurecht, Elke Rodriguez, Alexessander Couto Alves, Ashish Kumar, Patrick M. Sleiman, Xiao Chang, Carolina Medina-Gomez, Chen Hu, Cheng-jian Xu, Cancan Qi, Sarah El-Heis, Philip Titcombe, Elie Antoun, João Fadista, Carol A. Wang, Elisabeth Thiering, Baojun Wu, Sara Kress, Dilini M. Kothalawala, Latha Kadalayil, Jiasong Duan, Hongmei Zhang, Sabelo Hadebe, Thomas Hoffmann, Eric Jorgenson, Hélène Choquet, Neil Risch, Pål Njølstad, Ole A. Andreassen, Stefan Johansson, Catarina Almqvist, Tong Gong, Vilhelmina Ullemar, Robert Karlsson, Patrik K. E. Magnusson, Agnieszka Szwajda, Esteban G. Burchard, Jacob P. Thyssen, Torben Hansen, Line L. Kårhus, Thomas M. Dantoft, Alexander C.S.N. Jeanrenaud, Ahla Ghauri, Andreas Arnold, Georg Homuth, Susanne Lau, Markus M. Nöthen, Norbert Hübner, Medea Imboden, Alessia Visconti, Mario Falchi, Veronique Bataille, Pirro Hysi, Natalia Ballardini, Dorret I. Boomsma, Jouke J. Hottenga, Martina Müller-Nurasyid, Tarunveer S. Ahluwalia, Jakob Stokholm, Bo Chawes, Ann-Marie M. Schoos, Ana Esplugues, Mariona Bustamante, Benjamin Raby, Syed Arshad, Chris German, Tõnu Esko, Lili A. Milani, Andres Metspalu, Chikashi Terao, Katrina Abuabara, Mari Løset, Kristian Hveem, Bo Jacobsson, Maria Pino-Yanes, David P. Strachan, Niels Grarup, Allan Linneberg, Young-Ae Lee, Nicole Probst-Hensch, Stephan Weidinger, Marjo-Riitta Jarvelin, Erik Melén, Hakon Hakonarson, Alan D. Irvine, Deborah Jarvis, Tamar Nijsten, Liesbeth Duijts, Judith M. Vonk, Gerard H. Koppelmann, Keith M. Godfrey, Sheila J. Barton, Bjarke Feenstra, Craig E. Pennell, Peter D. Sly, Patrick G. Holt, L. Keoki Williams, Hans Bisgaard, Klaus Bønnelykke, John Curtin, Angela Simpson, Clare Murray, Tamara Schikowski, Supinda Bunyavanich, Scott T. Weiss, John W. Holloway, Josine L. Min, Sara J. Brown, Marie Standl, Lavinia Paternoster
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery N = 1,086,394, repli
Externí odkaz:
https://doaj.org/article/0be31a11c21947239dd707b702139765
Autor:
Alan D. Irvine, Thishi Surendranathan, Liz Hennessy, Ivana Rajkovic, Annette Durkan, Dearbhla Coughlan, Sean Conlon, Richard Hudson
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 465-478 (2023)
Abstract Background Management of paediatric atopic dermatitis (AD) remains challenging, and presents a considerable healthcare resource utilisation (HCRU) burden. Objectives To describe secondary HCRU for children and adolescents with moderate‐to
Externí odkaz:
https://doaj.org/article/b518e219101442acb1cadfd316fdb969
Autor:
Amy S. Paller, Carsten Flohr, Lawrence F. Eichenfield, Alan D. Irvine, Jamie Weisman, Jennifer Soung, Ana Pinto Correia, Chitra R. Natalie, Claudia Rodriguez Capriles, Evangeline Pierce, Sarah Reifeis, Renata Gontijo Lima, Clara Armengol Tubau, Vivian Laquer, Stephan Weidinger
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 7, Pp 1517-1534 (2023)
Abstract Introduction Atopic dermatitis (AD) is a chronic inflammatory skin disorder with limited treatment options for adolescents with moderate-to-severe disease. Lebrikizumab, a monoclonal antibody targeting interleukin (IL)-13, demonstrated clini
Externí odkaz:
https://doaj.org/article/f1994888427840c4b87a98813eff0651
Autor:
Angela L. Bosma, MD, Wouter Ouwerkerk, PhD, Madeline J. Heidema, MD, David Prieto-Merino, PhD, Michael R. Ardern-Jones, MD, PhD, Paula Beattie, MD, Sara J. Brown, MD, PhD, John R. Ingram, MD, PhD, Alan D. Irvine, MD, DSc, Graham Ogg, MD, PhD, Prakash Patel, BSc, Nick J. Reynolds, MD, PhD, R.M. Ross Hearn, MD, Mandy Wan, PhD, Richard B. Warren, MD, PhD, Richard T. Woolf, MD, PhD, Ariënna M. Hyseni, Louise A.A. Gerbens, MD, PhD, Phyllis I. Spuls, MD, PhD, Carsten Flohr, MD, PhD, Maritza A. Middelkamp-Hup, MD, PhD
Publikováno v:
JAAD International, Vol 10, Iss , Pp 14-24 (2023)
Background: Few data exist on differences in treatment effectiveness and safety in atopic dermatitis patients of different skin types. Objective: To investigate treatment outcomes of dupilumab, methotrexate, and ciclosporin, and morphological phenoty
Externí odkaz:
https://doaj.org/article/a6000db7359b4ce99fcb0c5dc46847c7
Publikováno v:
eLife, Vol 12 (2023)
Spectrins are membrane cytoskeletal proteins generally thought to function as heterotetramers comprising two α-spectrins and two β-spectrins. They influence cell shape and Hippo signaling, but the mechanism by which they influence Hippo signaling h
Externí odkaz:
https://doaj.org/article/4c24515777244cd5ad2cadee946016a5
Autor:
Anne Dompmartin, Eulalia Baselga, Laurence M. Boon, Andrea Diociaiuti, Veronika Dvorakova, May El Hachem, Paolo Gasparella, Emir Haxhija, Nader Ghaffarpour, Kristiina Kyrklund, Alan D. Irvine, Friedrich G. Kapp, Jochen Rößler, Päivi Salminen, Caroline van den Bosch, Carine van der Vleuten, Leo Schultze Kool, Miikka Vikkula
Publikováno v:
Journal of Vascular Anomalies, Vol 4, Iss 2, p e064 (2023)
Objective(s):. To elaborate expert consensus patient pathways to guide patients and physicians toward efficient diagnostics and management of patients with venous malformations. Methods:. VASCERN-VASCA (https://vascern.eu/) is a European network of m
Externí odkaz:
https://doaj.org/article/c0e5da68d8ac422abba0cd40b9c4244d
Autor:
Adelaide A. Hebert, Carsten Flohr, H. Chih-ho Hong, Alan D. Irvine, Evangeline Pierce, Hany Elmaraghy, Sreekumar Pillai, Zach Dawson, Sherry Chen, Clara Armengol, Elaine Siegfried, Stephan Weidinger
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractBackground Lebrikizumab, a high-affinity monoclonal antibody targeting IL-13, previously demonstrated clinical efficacy in three randomized, double-blind, placebo-controlled Phase 3 trials that included adults and adolescents with moderate-to
Externí odkaz:
https://doaj.org/article/b5ef1bb85af14e1fb68d15d4099d7b35