Výsledky vyhledávání - "D. I. de Pomerai"

A novel assay for the detection of anthelmintic activity mediated by cuticular damage to nematodes: validation on Caenorhabditis elegans exposed to cysteine proteinases

Autor: David J. Buttle, D. I. de Pomerai, Andrew Phiri, J. M. Behnke

Publikováno v: Parasitology. 144(5)

SUMMARYPlant cysteine proteinases (CPs) fromCarica papayakill parasitic and free-living nematodesin vitroby hydrolysis of the worm cuticle, a mechanism that is different to all commercially available synthetic anthelmintics. We have developed a cheap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825828cb2f033090938c2e2d4f8bdab4
https://pubmed.ncbi.nlm.nih.gov/28134060

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Developing a rapid throughput screen for detection of nematicidal activity of plant cysteine proteinases: the role ofCaenorhabditis eleganscystatins

Autor: Jerzy M. Behnke, Andrew Phiri, David J. Buttle, D. I. de Pomerai

Publikováno v: Parasitology. 141:164-180

SUMMARYPlant cysteine proteinases (CPs) from papaya (Carica papaya) are capable of killing parasitic nematode wormsin vitroand have been shown to possess anthelmintic effectsin vivo.The acute damage reported in gastrointestinal parasites has not been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee951cd57cd2dca4fd762577a2feddf9
https://doi.org/10.1017/s0031182013001364

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Microwave radiation induces a heat-shock response and enhances growth in the nematode Caenorhabditis elegans

Autor: Phillip Sewell, P. Candido, D. Jones, David Thomas, Joanna Allan, John E. H. Tattersall, Helen E. David, D. I. de Pomerai, Clare Daniells, Ian R. Duce, Mohammed H.A.Z. Mutwakil

Publikováno v: IEEE Transactions on Microwave Theory and Techniques. 48:2076-2081

This paper shows that prolonged (overnight) exposure to continuous microwave fields (750 MHz, 0.5 W) can induce both a heat-shock response and enhanced growth in the nematode worm Caenorhabditis elegans. Exposures were conducted in a TEM cell with ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cc56b5e877cbcfb7ea2f9a15a0a25e3
https://doi.org/10.1109/22.884198

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Stress-inducible transgenic nematodes as biomonitors of soil and water pollution

Autor: Clare Daniells, Rowena S. Power, E Wharf, R Wiseman, Axel Martinelli, Helen E. David, Joanne L. Dennis, Mohammed H.A.Z. Mutwakil, D. I. de Pomerai, Mari Ann Nowell, K Fletcher

Publikováno v: Journal of Biosciences. 23:513-526

This paper reviews the current status of nematodes with stress-inducible transgenes as biosensors responsive to a range of external stressors, e.g., soil or water pollution, microwave radiation or immunological attack. TransgenicCaenorhabditis elegan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eaed0a12994d22336427cac2a862f087
https://doi.org/10.1007/bf02936145

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Inter and Intra-Specific Genomic Variability of the Potato Cyst Nematodes Globodera Pallida and G. Rostochiensis From Europe and South America Using Rapd-Pcr

Autor: P. R. Burrows, I. F. Bendezu, M. Canto-Saenz, KA Evans, D. I. de Pomerai

Publikováno v: Nematologica. 44:49-61

Eleven populations of the potato cyst nematode Globodera pallida from the UK and Peru were analyzed and compared using RAPD-PCR with four 10-mer primers. In addition, seven populations of G. rostochiensis from the UK and single populations from Germa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e53f36ad111e201d630920f91eb4156
https://doi.org/10.1163/005225998x00064

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The measurement of immunological stress in nematodes

Autor: Mari Ann Nowell, Andrew J. Wardlaw, David I. Pritchard, D. I. de Pomerai

Publikováno v: Journal of Helminthology. 71:119-124

No article involving the nematode cuticle can ignore the work of Donald Lee. Since the publication of his book Physiology of nematodes (Lee, 1965), he has provided us with an extensive knowledge of the structure, composition, maintenance and growth o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed826aa4f61c72e3104646edf1da2b33
https://doi.org/10.1017/s0022149x00015789

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High-throughput analysis of multiple stress pathways using GFP reporters inC. elegans

Autor: D. Rajagopalan, Mainul Haque, John R. King, Ivan Lafayette, D. I. de Pomerai, Matthew Loose, Charumathi Anbalagan

Publikováno v: WIT Transactions on Ecology and the Environment.

Stress-responsive genes belonging to multiple defensive pathways in the nematode C. elegans are cross-regulated by kinase signalling (AKT-1/-2, p38 MAPK) and transcription factors (DAF-16, SKN-1). This cross-talk between stress pathways implies that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::775b383a4a74ed50d6215cd4f7516a94
https://doi.org/10.2495/etox100171

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A choice between glycogen and δ-crystallin accumulation is made in glial cells and not influenced by overlying neurons

Autor: Saleh Al Karim, D. I. de Pomerai

Publikováno v: Biochemical Journal. 285:79-83

Chick-embryo neuroretinal cells convert extensively into lens under low-glucose conditions, but this transdifferentiation process is blocked by high-glucose media. We have previously observed an inverse relationship between the levels of glycogen (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6e62ce0fc9935f351da2826717c826
https://doi.org/10.1042/bj2850079

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The effects of organic pesticides on inner membrane permeability in Escherichia coli ML35

Autor: Kemal Güven, M. Yolcu, Sait Erdogan, Reyhan Gul-Guven, D. I. de Pomerai

Publikováno v: Cell biology and toxicology. 21(2)

We have tested whether some pesticides might cause inner membrane leakage in ML35 Escherichia coli cells, which express beta-galactosidase (lacZ; EC 3.2.1.23) constitutively but lack the permease (lacY) required for substrate entry. The activity of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b504a6dfc5b3c009f3a718ac259868
https://pubmed.ncbi.nlm.nih.gov/16142582

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