Zobrazeno 1 - 10
of 29
pro vyhledávání: '"D. I. Bairamashvili"'
Publikováno v:
Тонкие химические технологии, Vol 9, Iss 2, Pp 3-31 (2014)
By now the pegylation of biologically active molecules including proteins with an inert hydrophilic polymer polyethylene glycol (PEG) is an important area in the new generation of prolonged-action pharmaceutical preparations. The conjugated molecules
Externí odkaz:
https://doaj.org/article/1a0b561f8794436abf2969907ed17acb
Publikováno v:
Тонкие химические технологии, Vol 2, Iss 1, Pp 26-33 (2007)
Scientific and conceptual basis of the new Master’s program “Technology of biopharmaceuticals” has been proposed. The development is illustrated by the use of a general organizational approach, which provides training of scientific and technolo
Externí odkaz:
https://doaj.org/article/42a17bf1e19b4b96b08cc41b75d1d8c4
Autor:
A G, Gabibov, N A, Ponomarenko, I I, Vorobyev, D I, Bairamashvili, V D, Knorre, A M, Shuster, V A, Martyanov, I K, Krylov, V A, Burmistrov, I I, Dedov, A I, Miroshnikov
Publikováno v:
Problemy endokrinologii. 53(2)
The development of modern pharmacology cannot be imagined without the use of genetic engineering methods (recombinant DNA technology). The success of medicine is increasingly based on the active use of protein preparations obtained using the technolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b58a8cae07ac6b1c054ffe8a76277714
https://pubmed.ncbi.nlm.nih.gov/31627572
https://pubmed.ncbi.nlm.nih.gov/31627572
Autor:
D. R. Tur, Natalia V. Grinberg, Alexei R. Khokhlov, Vladimir S. Papkov, Tatiana V. Burova, Alexander S. Dubovik, E. D. Shibanova, Valerij Ya. Grinberg, D. I. Bairamashvili
Publikováno v:
Langmuir. 29:2273-2281
Ternary interpolyelectrolyte complexes of insulin with biodegradable synthetic cationic polymer, poly(methylaminophosphazene) hydrochloride (PMAP), and dextran sulfate (DS) were investigated by means of turbidimetry, dynamic light scattering, phase a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95d3dc5a87ad94a688401ed0a496611
https://doi.org/10.1021/la303860t
https://doi.org/10.1021/la303860t
Autor:
A. M. Shuster, I. A. Puchkov, A. I. Bobruskin, N. V. Kononova, D. I. Bairamashvili, V. A. Mart’yanov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 38:479-487
In order to create an active pharmaceutical substance of the drug with prolonged action the modification of recombinant human granulocyte colony-stimulating factor GCSF (filgrastim) with polyethylene glycol (PEG, M 21.5 kDa) was conducted. A method f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e81b977e88297c72b21db317fc2aac0
https://doi.org/10.1134/s1068162012050111
https://doi.org/10.1134/s1068162012050111
Autor:
S. A. Kosarev, E. D. Shibanova, V. D. Gusarova, E. A. Evteeva, T. V. Vorob’eva, D. A. Gusarov, D. I. Bairamashvili, I. V. Sokolova
Publikováno v:
Pharmaceutical Chemistry Journal. 46:234-240
Much attention is presently devoted to the treatment of lymphoma using monoclonal antibodies. Unfortunately, preparations such as Rituximab (MabThera) are not produced in the Russian Federation and must be imported from abroad. It was shown that H1-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296b950bd72bc9466defd202a549e178
https://doi.org/10.1007/s11094-012-0769-1
https://doi.org/10.1007/s11094-012-0769-1
Publikováno v:
Russian Journal of Plant Physiology. 58:715-720
Low meadow-rue (Thalictrum minus L.) antioxidant complex was studied in cell extracts and culture medium. Its activity was expressed as total polyphenol content in ferulic acid equivalents. In these model systems (cell extracts and culture medium) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef152adb2ca100a102a8503c9b7d84ba
https://doi.org/10.1134/s1021443711040078
https://doi.org/10.1134/s1021443711040078
Autor:
N. V. Kononova, V. A. Mart’yanov, A. A. Zinchenko, A. A. Vainson, T. D. Melikhova, E. V. Sveshnikova, T. I. Kostromina, A. I. Bobruskin, A. V. Demin, D. I. Bairamashvili, A. M. Shuster
Publikováno v:
Applied Biochemistry and Microbiology. 46:726-732
Technology of industrial production of an active pharmaceutical substance (APS) of the recombinant human granulocyte colony-stimulating factor (rhG-CSF) involved the use of a highly productive E. coli strain capable of biosynthesis of rhG-CSF in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463e9a9c997047ce66762b527e88494f
https://doi.org/10.1134/s0003683810070082
https://doi.org/10.1134/s0003683810070082
Autor:
M. G. Akimov, E. D. Shibanova, D. I. Bairamashvili, G. N. Zinchenko, M. Yu. Bobrov, Fomina-Ageeva Ev, Vladimir V. Bezuglov, Dmitry V. Klinov, Anatoly I. Miroshnikov, Natalia Gretskaya
Publikováno v:
Russian Journal of Bioorganic Chemistry. 35:320-325
A preparation of nanocomplexes containing recombinant proteins (interferons alpha2b and beta1b, insulin, and human granulocyte colony stimulating factor) and natural polysialic acid (PSA) has been described. The incorporation of protein into the comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38216d38328b6424c64c682017306f0c
https://doi.org/10.1134/s1068162009030066
https://doi.org/10.1134/s1068162009030066
Publikováno v:
Journal of Chromatography B. 877:1216-1220
HPLC plays a key role in the preparative purification of human insulin. A21-desamidoinsulin is one of the impurities that possesses the chromatographic behavior similar to that of insulin and hence separation from this by-product is rather difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecce62a1b6f6c748255b94116915e61
https://doi.org/10.1016/j.jchromb.2009.02.062
https://doi.org/10.1016/j.jchromb.2009.02.062