Zobrazeno 1 - 10
of 374
pro vyhledávání: '"D. Hyndman"'
Publikováno v:
BioTechniques, Vol 20, Iss 6, Pp 1090-1097 (1996)
In the design of oligonucleotide sequences for targeting DNA or RNA sequences, it can be difficult to identify sequences that will hybridize only to the intended target. The term “sequence-specific” or “sequence-nonspecific” is often used to
Externí odkaz:
https://doaj.org/article/49e213064e834642b82c9b5c5d6978f5
Autor:
Timothy J Walker, Eduardo Reyes-Alvarez, Brandy D Hyndman, Michael G Sugiyama, Larissa CB Oliveira, Aisha N Rekab, Mathieu JF Crupi, Rebecca Cabral-Dias, Qianjin Guo, Patricia LM Dahia, Douglas S Richardson, Costin N Antonescu, Lois M Mulligan
Publikováno v:
eLife, Vol 12 (2024)
Internalization from the cell membrane and endosomal trafficking of receptor tyrosine kinases (RTKs) are important regulators of signaling in normal cells that can frequently be disrupted in cancer. The adrenal tumor pheochromocytoma (PCC) can be cau
Externí odkaz:
https://doaj.org/article/56671c5952a34e068944e75893122071
Autor:
R. D. Hyndman
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 24, Iss 7, Pp n/a-n/a (2023)
Abstract NW Canada and Alaska are the continuation of the North American Cordillera through Mexico, western USA and western Canada. I show that they have similar thermal regimes and thermal control of tectonics and seismicity. I first summarize the m
Externí odkaz:
https://doaj.org/article/309a4a03d99a4d73b23aef9b86e891ba
Geophysical and Geochemical Constraints on Neogene‐Recent Volcanism in the North American Cordillera
Autor:
Roy D. Hyndman, Dante Canil
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 22, Iss 5, Pp n/a-n/a (2021)
Abstract Widespread recent volcanic rocks occur across the Cordillera landward of the current/recent volcanic arc Mexico to Alaska and most other subduction backarcs. We conclude that most are produced by partial melt in the upper asthenosphere where
Externí odkaz:
https://doaj.org/article/d31c036799414d3480c48a10ce08bf63
Autor:
M. Riedel, K. M. M. Rohr, G. D. Spence, D. Kelley, J. Delaney, L. Lapham, J. W. Pohlman, R. D. Hyndman, E. C. Willoughby
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 21, Iss 8, Pp n/a-n/a (2020)
Abstract Geophysical and geochemical data indicate there is abundant fluid expulsion in the Nootka fault zone (NFZ) between the Juan de Fuca and Explorer plates and the Nootka continental slope. Here we combine observations from >20 years of investig
Externí odkaz:
https://doaj.org/article/1b04e190ebb241689cb873b8e6e8d7c3
Autor:
Dante Canil, Roy D. Hyndman
Publikováno v:
Canadian Journal of Earth Sciences.
We have estimated the geochemical equilibration depth and temperature of the widespread Neogene alkaline basalts in the Cordillera of Alaska, Northwest Canada, and in Mexico using geobarometry on bulk compositions that have been minimally differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8431e21798a7df536ed480730893d25c
https://doi.org/10.1139/cjes-2023-0005
https://doi.org/10.1139/cjes-2023-0005
Autor:
Kristin M. M. Rohr, George D. Spence, Cord Papenberg, S. Yelisetti, Michelle M. Côté, Roy D. Hyndman, Thomas S. James, Michael Riedel
Publikováno v:
Geosphere. 17:23-38
A well-recorded Mw 7.8 megathrust earthquake occurred on 27 October 2012 under the Queen Charlotte terrace off the west coast of Haida Gwaii, western Canada. In this study, we supplement limited earlier seismic refraction work on the offshore velocit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af599c881d21eacbaeab8f681e753965
https://doi.org/10.1130/ges02258.1
https://doi.org/10.1130/ges02258.1
Publikováno v:
Oncogene. 39:6493-6510
Pancreatic ductal adenocarcinoma (PDAC) is a therapeutically challenging disease with poor survival rates, owing to late diagnosis and early dissemination. These tumors frequently undergo perineural invasion, spreading along nerves regionally and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1845580c1c77d14409074d12c8e49d
https://doi.org/10.1038/s41388-020-01448-z
https://doi.org/10.1038/s41388-020-01448-z
Autor:
K. Ramachandran, R. D. Hyndman
Publikováno v:
Solid Earth, Vol 3, Iss 1, Pp 121-129 (2012)
Large amounts of water carried down in subduction zones are driven upward into the overlying forearc upper mantle and crust as increasing temperatures and pressure dehydrate the subducting crust. Through seismic tomography velocities we show (a) the
Externí odkaz:
https://doaj.org/article/8a0a397f3a4143609deb6e342c87cf0e
Autor:
Roy D. Hyndman
Publikováno v:
Journal of Geophysical Research: Solid Earth. 124:2057-2079
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::400cf37817689493801d2afcb92d19a0
https://doi.org/10.1029/2018jb016697
https://doi.org/10.1029/2018jb016697