Výsledky vyhledávání

Structure and mechanism of DNA delivery of a gene transfer agent

Autor: J. Thomas Beatty, T. Fuzik, Pavol Bárdy, D. Hrebik, Roman Pantůček, Pavel Plevka

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications

Alphaproteobacteria, which are the most abundant microorganisms of temperate oceans, produce phage-like particles called gene transfer agents (GTAs) that mediate lateral gene exchange. However, the mechanism by which GTAs deliver DNA into cells is un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c9cd9f050a300a50a9b86d9d8e4cee
https://doaj.org/article/205d0c3e3d524f7a8f245523800b58b3

Zobrazit plný text záznamu

Preparation of nanoliposomes by microfluidic mixing in herring-bone channel and the role of membrane fluidity in liposomes formation

Autor: Kamila Velínská, Josef Mašek, Stuart Macaulay, Milan Raska, Jaroslav Turánek, Irena Kratochvílová, Andrea Tomečková, František Hubatka, Jan Kotouček, Eliška Bartheldyová, Martina Fojtíková, Jana Stráská, D. Hrebik, Pavel Kulich, Jaroslava Bezděková

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

Introduction of microfluidic mixing technique opens a new door for preparation of the liposomes and lipid-based nanoparticles by on-chip technologies that are applicable in a laboratory and industrial scale. This study demonstrates the role of phosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b82cd9ecf3dcc0e7f2b5fe8db8be774
http://link.springer.com/article/10.1038/s41598-020-62500-2

Zobrazit plný text záznamu

Plný text ve formátu HTML

Virion Structure and In Vitro Genome Release Mechanism of Dicistrovirus Kashmir Bee Virus

Autor: Liya Mukhamedova, Antonín Přidal, T. Fuzik, Jiří Nováček, Diego M. A. Guérin, Pavel Plevka, Gerardo Anibal Marti, D. Hrebik

Publikováno v: Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
instname

Infections of Kashmir bee virus (KBV) are lethal for honeybees and have been associated with colony collapse disorder. KBV and closely related viruses contribute to the ongoing decline in the number of honeybee colonies in North America, Europe, Aust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fdea4c38b3290dadec371be108f915
https://doi.org/10.1128/jvi.01950-20

Zobrazit plný text záznamu

ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating

Autor: Mária Gondová, T. Fuzik, Lenka Šmerdová, D. Hrebik, Pavel Plevka, Ondrej Šedo, Zbyněk Zdráhal, Athanassios Adamopoulos

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Medical visits and missed days of school and work caused by rhinoviruses cost tens of billions of US dollars annually. Currently, there are no antivirals against rhinoviruses, and the available treatments only treat the symptoms. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03277e935470ff31cdc9a481fa1e8058
https://doi.org/10.1073/pnas.2024251118

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Structure and genome ejection mechanism of Staphylococcus aureus phage P68

Autor: D. Hrebik, T. Fuzik, K. Skubnik, Pavel Plevka, Roman Pantůček, Dana Štveráková

Publikováno v: Science Advances

Cryo-EM reveals the genome ejection mechanism of bacteriophage P68, a potential phage therapy agent against Staphylococcus aureus.
Phages infecting Staphylococcus aureus can be used as therapeutics against antibiotic-resistant bacterial infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6434edd1edcd5d6f2b9ee477a268b27
https://doi.org/10.1126/sciadv.aaw7414

Zobrazit plný text záznamu

Gadolinium labelled nanoliposomes as the platform for MRI theranostics: in vitro safety study in liver cells and macrophages

Autor: Jiřina Procházková, Jan Kotouček, Jaroslav Turánek, Josef Slavík, Kateřina Pěnčíková, Stuart Macaulay, František Hubatka, Pavlína Šimečková, Pavel Kulich, D. Hrebik, Robert Mikulik, Jiří Neča, Josef Mašek, Pavlína Turánek Knotigová, Miroslav Machala, Ondrej Kováč, Milan Raska, Jana Stráská, Pavel Diviš

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Gadolinium (Gd)–based contrast agents are extensively used for magnetic resonance imaging (MRI). Liposomes are potential nanocarrier–based biocompatible platforms for development of new generations of MRI diagnostics. Liposomes with Gd–complexe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f8dd66d62886cd20729cb61f50197f
https://pubmed.ncbi.nlm.nih.gov/32179785

Zobrazit plný text záznamu

Enterovirus particles expel capsid pentamers to enable genome release

Autor: Robert Vácha, Jana Moravcová, T. Fuzik, Pavel Plevka, Lukáš Sukeník, Yevgen Levdansky, Liya Mukhamedova, D. Hrebik, David Buchta

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)

Viruses from the genus Enterovirus are important human pathogens. Receptor binding or exposure to acidic pH in endosomes converts enterovirus particles to an activated state that is required for genome release. However, the mechanism of enterovirus u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57be56767413a05125a5767a0c64a50
http://europepmc.org/articles/PMC6408523

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání