Zobrazeno 1 - 10
of 272
pro vyhledávání: '"D. Houtman"'
Autor:
Aline Sandouk, Zhen Xu, Sankar Baruah, Mikaela Tremblay, Jesse B. Hopkins, Srinivas Chakravarthy, Lokesh Gakhar, Nicholas J. Schnicker, Jon C. D. Houtman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract GRB2 is an adaptor protein required for facilitating cytoplasmic signaling complexes from a wide array of binding partners. GRB2 has been reported to exist in either a monomeric or dimeric state in crystal and solution. GRB2 dimers are forme
Externí odkaz:
https://doaj.org/article/dfd8a538987e4db2abc48518bca57d01
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Glycerol monolaurate (GML) is a naturally occurring antimicrobial agent used commercially in numerous products and food items. GML is also used as a homeopathic agent and is being clinically tested to treat several human diseases. In additio
Externí odkaz:
https://doaj.org/article/654d8d0b3ead4a838e4c1eb63b5d123e
Autor:
Amira Zaher, Laura M. Stephens, Ann M. Miller, Stacey M. Hartwig, Jeffrey M. Stolwijk, Michael S. Petronek, Zeb R. Zacharias, Thaddeus J. Wadas, Varun Monga, Joseph J. Cullen, Muhammad Furqan, Jon C. D. Houtman, Steven M. Varga, Douglas R. Spitz, Bryan G. Allen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pharmacological ascorbate (i.e., intravenous infusions of vitamin C reaching ~ 20 mM in plasma) is under active investigation as an adjuvant to standard of care anti-cancer treatments due to its dual redox roles as an antioxidant in normal tissues an
Externí odkaz:
https://doaj.org/article/ae800cab6bcd4188b2c0616a5d74bf80
Autor:
Micaela G. Fosdick, Pratik Rajesh Chheda, Phuong M. Tran, Alex Wolff, Ronal Peralta, Michael Y. Zhang, Robert Kerns, Jon C. D. Houtman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glycerol monolaurate (GML), a naturally occurring monoglyceride, is widely used commercially for its antimicrobial properties. Interestingly, several studies have shown that GML not only has antimicrobial properties but is also an anti-infla
Externí odkaz:
https://doaj.org/article/3f0a0641182b469a9ee320d86e8250d8
Autor:
Maartje C. Bakhuys Roozeboom, Roosmarijn M. C. Schelvis, Irene L. D. Houtman, Noortje M. Wiezer, Paulien M. Bongers
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Work stress is an important problem among employees in education in the Netherlands. The present study aims to investigate the effects of a participatory organizational level work stress prevention approach to reduce (quantitative
Externí odkaz:
https://doaj.org/article/83976c9692e149bea03b001de9beed3b
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background The aim of this study is to develop a new measure for the concept of mental retirement and test the construct validity of the measure. Employees who are ‘mentally retired’ are present at their work physically, but have already
Externí odkaz:
https://doaj.org/article/8936cc290b1e49588d2da4a888081ddb
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The present study aimed to investigate the effects of a stepwise, bottom-up participatory program with a tailor-made intervention process addressing the level of mental retirement in a sample of Dutch employees. Mental retirement
Externí odkaz:
https://doaj.org/article/77be9183e66b48cfad2abe72cb3a5095
Autor:
Rianne J. A. Hoek, Bo M. Havermans, Irene L. D. Houtman, Evelien P. M. Brouwers, Yvonne F. Heerkens, Moniek C. Zijlstra-Vlasveld, Johannes R. Anema, Allard J. van der Beek, Cécile R. L. Boot
Publikováno v:
BMC Public Health, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Adequate implementation of work-related stress management interventions can reduce or prevent work-related stress and sick leave in organizations. We developed a multifaceted integral stress-prevention strategy for organizations f
Externí odkaz:
https://doaj.org/article/72cade49a4e34e42a3c89435156ffd4e
Autor:
Bo M. Havermans, Cécile R. L. Boot, Irene L. D. Houtman, Evelien P. M. Brouwers, Johannes R. Anema, Allard J. van der Beek
Publikováno v:
BMC Public Health, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background Health care workers are exposed to psychosocial work factors. Autonomy and social support are psychosocial work factors that are related to stress, and are argued to largely result from the psychosocial safety climate within organ
Externí odkaz:
https://doaj.org/article/74deb9d1e80d4cb1a57ad66e773639bb
Autor:
Alicia M. Wallis, Ellie C. Wallace, Bruce S. Hostager, Zuoan Yi, Jon C. D. Houtman, Gail A. Bishop
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The adaptor protein TNF receptor associated factor (TRAF) 3 is required for effective TCR signaling and normal T cell effector functions, and associates with the CD3/CD28 complex upon activation. To determine how TRAF3 promotes proximal TCR
Externí odkaz:
https://doaj.org/article/193ddd2d1b1a4ac4ac05b3cd822eef66