Cardiac events among a cohort of 17,389 patients receiving cancer chemotherapy: short and long term implications

Autor: Saifei Liu, John D. Horowitz, Bogda Koczwara, Aaron L. Sverdlov, Natalie Packer, Robyn A. Clark

Publikováno v: Cardio-Oncology, Vol 10, Iss 1, Pp 1-11 (2024)

Abstract Background The association between cardiovascular disease and carcinogenesis is bidirectional and well-established. Furthermore, cancer treatment improves overall patient survival, potentially at the cost of incremental and fatal cardiovascu

Externí odkaz: https://doaj.org/article/80443f6f88e14947a8018773960f12af

Coronary 'Microvascular Dysfunction': Evolving Understanding of Pathophysiology, Clinical Implications, and Potential Therapeutics

Autor: Chun Yeung Kei, Kuljit Singh, Rustem F. Dautov, Thanh H. Nguyen, Yuliy Y. Chirkov, John D. Horowitz

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 14, p 11287 (2023)

Until recently, it has been generally held that stable angina pectoris (SAP) primarily reflects the presence of epicardial coronary artery stenoses due to atheromatous plaque(s), while acute myocardial infarction (AMI) results from thrombus formation

Externí odkaz: https://doaj.org/article/c8d969f6aa9a434494509338730de773

Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry

Autor: Ken Kato, Victoria L. Cammann, L. Christian Napp, Konrad A. Szawan, Jozef Micek, Sara Dreiding, Rena A. Levinson, Vanya Petkova, Michael Würdinger, Alexandru Patrascu, Rafael Sumalinog, Sebastiano Gili, Christian F. Clarenbach, Malcolm Kohler, Manfred Wischnewsky, Rodolfo Citro, Carmine Vecchione, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Benjamin Meder, Milosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Wolfgang Dichtl, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Marco Roffi, Adrian Banning, Mathias Wolfrum, Florim Cuculi, Richard Kobza, Thomas A. Fischer, Tuija Vasankari, K.E. Juhani Airaksinen, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El‐Battrawy, Ibrahim Akin, Martin Kozel, Petr Tousek, David E. Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho‐Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Masanori Sano, Iwao Ishibashi, Masayuki Takahara, Toshiharu Himi, Yoshio Kobayashi, Abhiram Prasad, Charanjit S. Rihal, Kan Liu, P. Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Gonçalo Pestana, Thanh H. Nguyen, Michael Böhm, Lars S. Maier, Fausto J. Pinto, Petr Widimský, Stephan B. Felix, Grzegorz Opolski, Ruediger C. Braun‐Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M. Pieske, Heribert Schunkert, Martin Borggrefe, Holger Thiele, Johann Bauersachs, Hugo A. Katus, John D. Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J. Bax, Thomas F. Lüscher, Frank Ruschitzka, Jelena R. Ghadri, Christian Templin

Publikováno v: ESC Heart Failure, Vol 8, Iss 3, Pp 1924-1932 (2021)

Abstract Aims Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence of acute pulmonary triggers in patients with TTS and their impact on outcomes. Methods and results Patients wi

Externí odkaz: https://doaj.org/article/11a498a4fc9547008d324ffd45210f81

Effects of Soluble Guanylate Cyclase Stimulators and Activators on Anti-Aggregatory Signalling in Patients with Coronary Artery Spasm

Autor: Armin Muminovic, Yuliy Y. Chirkov, John D. Horowitz

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 11, p 9273 (2023)

Impairment of the nitric oxide/soluble guanylate cyclase (NO)/sGC) signalling cascade is associated with many forms of cardiovascular disease, resulting not only in compromised vasodilatation but also loss of anti-aggregatory homeostasis. Myocardial

Externí odkaz: https://doaj.org/article/392322b12e254db7891c61b31af9d34e

Prognostic value of texture analysis from cardiac magnetic resonance imaging in patients with Takotsubo syndrome: a machine learning based proof-of-principle approach

Autor: Manoj Mannil, Ken Kato, Robert Manka, Jochen von Spiczak, Benjamin Peters, Victoria L. Cammann, Christoph Kaiser, Stefan Osswald, Thanh Ha Nguyen, John D. Horowitz, Hugo A. Katus, Frank Ruschitzka, Jelena R. Ghadri, Hatem Alkadhi, Christian Templin

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

Abstract Cardiac magnetic resonance (CMR) imaging has become an important technique for non-invasive diagnosis of takotsubo syndrome (TTS). The long-term prognostic value of CMR imaging in TTS has not been fully elucidated yet. This study sought to e

Externí odkaz: https://doaj.org/article/8b9558fcbb414f078925eee1ae9987cc