Zobrazeno 1 - 10
of 4 814
pro vyhledávání: '"D. Hommel"'
The neuroanatomical organization of the hypothalamus is driven by spatial and topological efficiency
Autor:
Nathan R. Smith, Shabeeb Ameen, Sierra N. Miller, James M. Kasper, Jennifer M. Schwarz, Jonathan D. Hommel, Ahmad Borzou
Publikováno v:
Frontiers in Systems Neuroscience, Vol 18 (2024)
The hypothalamus in the mammalian brain is responsible for regulating functions associated with survival and reproduction representing a complex set of highly interconnected, yet anatomically and functionally distinct, sub-regions. It remains unclear
Externí odkaz:
https://doaj.org/article/732140f6fd0a4fb08b7891489e3ea3f0
Autor:
Catherine M. Sampson, Andrea L. Dimet, Harshini Neelakantan, Kehinde O. Ogunseye, Heather L. Stevenson, Jonathan D. Hommel, Stanley J. Watowich
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Obesity is a large and growing global health problem with few effective therapies. The present study investigated metabolic and physiological benefits of nicotinamide N-methyltransferase inhibitor (NNMTi) treatment combined with a lean diet
Externí odkaz:
https://doaj.org/article/87f2fa77c3f847f5b4521dfa072c052a
Autor:
Ashley E. Smith, Kehinde O. Ogunseye, Julia N. DeBenedictis, Joanna Peris, James M. Kasper, Jonathan D. Hommel
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Food intake is a complex behavior regulated by discrete brain nuclei that integrate homeostatic nutritional requirements with the hedonic properties of food. Homeostatic feeding (i.e. titration of caloric intake), is typically associated wit
Externí odkaz:
https://doaj.org/article/58cd59baf2604989a5e5eae9fd3f6bde
Autor:
Sierra N. Miller, Holly Chapman, James Kasper, Ashley E. Smith, Noelle Anastasio, Jonathan D. Hommel
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 78-79 (2022)
OBJECTIVES/GOALS: The primary goals of this study are 1) expand our understanding of the neural circuitry influenced by the neuropeptide Neuromedin U (NMU) via its receptor Neuromedin U Receptor 2 (NMUR2), and 2) provide alternative top-down mechanis
Externí odkaz:
https://doaj.org/article/944019f1a00248e08522741e1269c51d
Autor:
Federico Scala, Miroslav N. Nenov, Elizabeth J. Crofton, Aditya K. Singh, Oluwarotimi Folorunso, Yafang Zhang, Brent C. Chesson, Norelle C. Wildburger, Thomas F. James, Musaad A. Alshammari, Tahani K. Alshammari, Hannah Elfrink, Claudio Grassi, James M. Kasper, Ashley E. Smith, Jonathan D. Hommel, Cheryl F. Lichti, Jai S. Rudra, Marcello D’Ascenzo, Thomas A. Green, Fernanda Laezza
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 555-567 (2018)
Summary: Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na+ channel Nav1.6
Externí odkaz:
https://doaj.org/article/dc94cfdd1eef4764a9b23adba0a07db4
Autor:
Amanda E. Price, Victoria D. Brehm, Jonathan D. Hommel, Noelle C. Anastasio, Kathryn A. Cunningham
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Binge eating disorder (BED) is characterized by dysregulated feeding and reward-related processes, and treatment is often challenged by limited therapeutic options. The serotonin (5-HT) 5-HT2A receptor (5-HT2AR) and 5-HT2CR are implicated in both fee
Externí odkaz:
https://doaj.org/article/b1f07ce34d3c4863848e8181ca763eaf
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Cocaine use disorder (CUD) is characterized by repeated cycles of drug seeking and drug taking. Currently, there are no available pharmacotherapies to treat CUD, partially due to a lack of a mechanistic understanding of cocaine-evoked alterations in
Externí odkaz:
https://doaj.org/article/c1f87da2d8b547b583c8e7a81d8576e5
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Publikováno v:
Acta Physica Polonica A. 141:105-109
Autor:
E. Piskorska-Hommel, V. Holy, O. Caha, A. Wolska, A. Gust, C. Kruse, H. Kroncke, J. Falta, D. Hommel
Publikováno v:
Journal of Alloys and Compounds. 949:169782