Zobrazeno 1 - 10
of 369
pro vyhledávání: '"D. Hermes"'
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy
Autor:
R. Fledrich, T. Abdelaal, L. Rasch, V. Bansal, V. Schütza, B. Brügger, C. Lüchtenborg, T. Prukop, J. Stenzel, R. U. Rahman, D. Hermes, D. Ewers, W. Möbius, T. Ruhwedel, I. Katona, J. Weis, D. Klein, R. Martini, W. Brück, W. C. Müller, S. Bonn, I. Bechmann, K. A. Nave, R. M. Stassart, M. W. Sereda
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Charcot–Marie–Tooth disease 1A (CMT1A) is a peripheral demyelinating disease. Here, the authors demonstrate in a rodent model of CMT1A that Schwann cells have impairments in lipid biosynthesis, and that restoring lipids via diet can reverse the d
Externí odkaz:
https://doaj.org/article/8b8e4e83c023447f9c6cbe01a5ec8a8b
Autor:
J. B. Potoine, R. Bruce, R. Cai, F. Cerutti, M. D’Andrea, L. Esposito, P. D. Hermes, A. Lechner, D. Mirarchi, S. Redaelli, V. Rodin, F. Salvat Pujo, P. Schoofs, A. Waets, F. Wrobel
Publikováno v:
Physical Review Accelerators and Beams, Vol 26, Iss 9, p 093001 (2023)
The LHC heavy-ion program with ^{208}Pb^{82+} beams will benefit from a significant increase of the beam intensity when entering its high-luminosity era in Run 3 (2023). The stored energy is expected to surpass 20 MJ per beam. The LHC is equipped wit
Externí odkaz:
https://doaj.org/article/a0176cdbf6c54b7db3b6be09f046d5cf
Autor:
Matthew S. Johnson, Maciej Gierada, Eric D. Hermes, David H. Bross, Khachik Sargsyan, Habib N. Najm, Judit Zador
Many important industrial processes rely on heterogeneous catalytic systems. However, given all possible catalysts and conditions of interest it is impractical to optimize most systems experimentally. Automatically generated microkinetic models can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::babc135bae99f3a36ce71075e8d03e92
https://doi.org/10.26434/chemrxiv-2023-2xpfq
https://doi.org/10.26434/chemrxiv-2023-2xpfq
Akademický článek
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Representing high throughput expression profiles via perturbation barcodes reveals compound targets.
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 2, p e1005335 (2017)
High throughput mRNA expression profiling can be used to characterize the response of cell culture models to perturbations such as pharmacologic modulators and genetic perturbations. As profiling campaigns expand in scope, it is important to homogeni
Externí odkaz:
https://doaj.org/article/9ef656e486684a0cb10a586c64ff5b5d
We present a new algorithm for the optimization of molecular structures to saddle points on the potential energy surface using a redundant internal coordinate system. This algorithm automates the procedure of defining the internal coordinate system,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa72ff0c97aeb91bfdbbb4407cf23321
https://doi.org/10.26434/chemrxiv-2022-44r17
https://doi.org/10.26434/chemrxiv-2022-44r17
Autor:
D. van Blooijs, M.A. van den Boom, J.F. van der Aar, G.J.M. Huiskamp, G. Castegnaro, M. Demuru, W.J.E.M. Zweiphenning, P. van Eijsden, K. J. Miller, F.S.S. Leijten, D. Hermes
The structure of the human connectome develops from childhood throughout adolescence to middle age, but how this affects the speed of neuronal signaling is not well described. To understand the maturation process of transmission speed across the conn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c82aa6b5e8b8f7c130aab069a02917
https://doi.org/10.1101/2022.03.14.484297
https://doi.org/10.1101/2022.03.14.484297
We present a new geodesic-based method for geometry optimization in a basis of redundant internal coordinates. Our method updates the molecular geometry by following the geodesic generated by a displacement vector on the internal coordinate manifold,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8f7f2152c7858c294683241f287fd1
https://doi.org/10.26434/chemrxiv-2021-r1dmp-v3
https://doi.org/10.26434/chemrxiv-2021-r1dmp-v3
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
We present a new geodesic-based method for geometry optimization in a basis of redundant internal coordinates.This method realizes displacements along internal coordinates by following the geodesic generated by the displacement vector on the internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3412cd9ec9a6903ccd42fedce155997
https://doi.org/10.26434/chemrxiv.14681424.v1
https://doi.org/10.26434/chemrxiv.14681424.v1