Zobrazeno 1 - 10
of 1 424
pro vyhledávání: '"D. Heiss"'
Autor:
V. Dolores-Calzadilla, B. Romeira, F. Pagliano, S. Birindelli, A. Higuera-Rodriguez, P. J. van Veldhoven, M. K. Smit, A. Fiore, D. Heiss
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Despite much progress, nanoscale light sources suitable for photonic integration are lacking. Here, the authors present a metal-cavity nanopillar LED on a silicon substrate working at telecommunications wavelengths, which demonstrates compatibility w
Externí odkaz:
https://doaj.org/article/a3209aae4eb14a198efef9c09f18e4b1
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Glioblastoma (GBM) comprises 45.6% of all primary malignant brain cancers and is one of the most common and aggressive intracranial tumors in adults. Intratumoral heterogeneity with a wide range of proteomic, genetic, and epigenetic dysregul
Externí odkaz:
https://doaj.org/article/add735e8d2144017b4517284089db22c
Autor:
Sarah R. Rivas, Mynor J. Mendez Valdez, Jay S. Chandar, Jelisah F. Desgraves, Victor M. Lu, Leo Ampie, Eric B. Singh, Deepa Seetharam, Christian K. Ramsoomair, Anna Hudson, Shreya M. Ingle, Vaidya Govindarajan, Tara T. Doucet-O’Hare, Catherine DeMarino, John D. Heiss, Avindra Nath, Ashish H. Shah
Publikováno v:
Cancers, Vol 16, Iss 9, p 1754 (2024)
Outcomes for glioblastoma (GBM) remain poor despite standard-of-care treatments including surgical resection, radiation, and chemotherapy. Intratumoral heterogeneity contributes to treatment resistance and poor prognosis, thus demanding novel therape
Externí odkaz:
https://doaj.org/article/84becb1793e6493e936299f35f6baecf
Autor:
Smit P. Shah, John D. Heiss
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 228 (2024)
Neurology is a quickly evolving specialty that requires clinicians to make precise and prompt diagnoses and clinical decisions based on the latest evidence-based medicine practices. In all Neurology subspecialties—Stroke and Epilepsy in particular
Externí odkaz:
https://doaj.org/article/5c9cd6250e744a6c866efb35b11fa4a8
Autor:
Danielle D. Dang, Vikram Chandrashekhar, Vibhu Chandrashekhar, Nagela Ghabdanzanluqui, Russell H. Knutsen, Matthew A. Nazari, Likitha Nimmagadda, Danielle R. Donahue, Dorian B. McGavern, Beth A. Kozel, John D. Heiss, Karel Pacak, Zhengping Zhuang, Jared S. Rosenblum
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102367- (2023)
Summary: Mapping cranial vasculature and adjacent neurovascular interfaces in their entirety will enhance our understanding of central nervous system function in any physiologic state. We present a workflow to visualize in situ murine vasculature and
Externí odkaz:
https://doaj.org/article/ae9471c45db847b68da91dbec8d63a83
Autor:
Ashish H. Shah, Sarah R. Rivas, Tara T. Doucet-O’Hare, Vaidya Govindarajan, Catherine DeMarino, Tongguang Wang, Leonel Ampie, Yong Zhang, Yeshavanth Kumar Banasavadi-Siddegowda, Stuart Walbridge, Dragan Maric, Marta Garcia-Montojo, Robert K. Suter, Myoung-Hwa Lee, Kareem A. Zaghloul, Joseph Steiner, Abdel G. Elkahloun, Jay Chandar, Deepa Seetharam, Jelisah Desgraves, Wenxue Li, Kory Johnson, Michael E. Ivan, Ricardo J. Komotar, Mark R. Gilbert, John D. Heiss, Avindra Nath
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8% of the human genome. Although normally silenced, the most recently integrated provirus HERV-K (HML-2) can be reactivated in certain cancers. Here, we report pa
Externí odkaz:
https://doaj.org/article/b841f1b345c0461faf2a96f0d318229b
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Epigenetic mechanisms allow cells to fine-tune gene expression in response to environmental stimuli. For decades, it has been known that mitochondria have genetic material. Still, only recently have studies shown that epigenetic factors regulate mito
Externí odkaz:
https://doaj.org/article/a1f9e856d9014ccf8f6b7f9079814d86
Autor:
Aimee L. Dowling, Stuart Walbridge, Celine Ertekin, Sriya Namagiri, Krystal Camacho, Ashis Chowdhury, Jean-Paul Bryant, Eric Kohut, John D. Heiss, Desmond A. Brown, Sangamesh G. Kumbar, Yeshavanth Kumar Banasavadi-Siddegowda
Publikováno v:
Cells, Vol 12, Iss 21, p 2562 (2023)
Glioblastoma is the most common malignant primary brain tumor. The outcome is dismal, despite the multimodal therapeutic approach that includes surgical resection, followed by radiation and chemotherapy. The quest for novel therapeutic targets to tre
Externí odkaz:
https://doaj.org/article/a2a25bc8c4914f2f9d2697c28c7973a6
Autor:
Eric A. Kohut, Shantelle A. Graff, Samuel H. Wakelin, Martin Arhin, Govind Nair, John D. Heiss
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 21, p 6725 (2023)
Neurosurgeons evaluate MRI scans to document whether surgical treatment has reduced syrinx size. Manual measurement of syrinx volume is time-consuming and potentially introduces operator error and bias. Developing convenient semiautomated volumetric
Externí odkaz:
https://doaj.org/article/ada2127fe6574424819112a517f78dae
Autor:
Hannah P. Famili, Christopher K. Zalewski, Alaaddin Ibrahimy, Jessica Mack, Fredric Cantor, John D. Heiss, Carmen C. Brewer
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 8, p 2767 (2023)
Chiari Malformation Type I (CM1) is a neurological condition in which the cerebellar tonsils extend past the foramen magnum. While many studies have reported dizziness symptoms in patients with CM1, the prevalence of peripheral labyrinthine lesions i
Externí odkaz:
https://doaj.org/article/35781ce60bd4431596cb420a80513ee3