Zobrazeno 1 - 10
of 70
pro vyhledávání: '"D. Hamblin"'
Autor:
Oliver C. Lomas, Sarah Gooding, Maite Cabes, Helene Dreau, Edward Wilson, Paolo Polzella, Genomics England Research Consortium, Karthik Ramasamy, Angela D. Hamblin
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 809-812 (2021)
Abstract Multiple myeloma is characterized by chromosomal abnormalities and genetic variation, which may inform prognosis and guide treatment. This pilot study sought to examine the feasibility of incorporating Whole Genome Sequencing (WGS) alongside
Externí odkaz:
https://doaj.org/article/0907cfd5cbae46de90683fdc9405e99f
Akademický článek
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Publikováno v:
Haematologica, Vol 97, Iss 11 (2012)
Externí odkaz:
https://doaj.org/article/ef5ffcdf28494365965718ac856e3b02
Autor:
John D. Bagert, Alborz Mahdavi, Erin M. Schuman, Graham D. Hamblin, Cathy Dong, Michael J. Sweredoski, Sonja Hess, Granton A. Jindal, David A. Tirrell
Publikováno v:
Journal of the American Chemical Society
Methods for cell-selective analysis of proteome dynamics will facilitate studies of biological processes in multicellular organisms. Here we describe a mutant murine methionyl-tRNA synthetase (designated L274GMmMetRS) that charges the noncanonical am
Publikováno v:
Nature Chemistry. 7:295-300
DNA nanotubes offer a high aspect ratio and rigidity, attractive attributes for the controlled assembly of hierarchically complex linear arrays. It is highly desirable to control the positioning of rungs along the backbone of the nanotubes, minimize
Autor:
Robert Godin, Graham D. Hamblin, Amani A. Hariri, Hanadi F. Sleiman, Gonzalo Cosa, Paul W. Wiseman, Jean-Francois Desjardins, Jack S. Hardwick
Publikováno v:
Bioconjugate chemistry. 28(9)
A wide variety of approaches have become available for the fabrication of nanomaterials with increasing degrees of complexity, precision, and speed while minimizing cost. Their quantitative characterization, however, remains a challenge. Analytical m
Autor:
Karina M. M. Carneiro, Lawrence Panasci, Hanadi F. Sleiman, Joel Neves Briard, Lilian Amrein, Antoine G. Godin, Paul W. Wiseman, Thomas G. W. Edwardson, Graham D. Hamblin, Johans Fakhoury, Katherine E. Bujold
Publikováno v:
Chem. Sci.. 5:2449-2455
Here, we demonstrate a new approach for the design and assembly of a dynamic DNA cube with an addressable cellular uptake profile. This cube can be selectively unzipped from a 3D to a flat two-dimensional structure in the presence of a specific nucle
Autor:
Ted H. Hansen, Ruth R. French, Angela D. Hamblin, Ben C. King, Martin J. Glennie, Peter Johnson, Philip Savage, Leon Douglas
Publikováno v:
Cancer Immunology, Immunotherapy. 62:1093-1105
Attempts to generate robust anti-tumour cytotoxic T lymphocyte (CTL) responses using immunotherapy are frequently thwarted by exhaustion and anergy of CTL recruited to tumour. One strategy to overcome this is to retarget a population of virus-specifi
Autor:
Karina M. M. Carneiro, Amani A. Hariri, Kai L. Lau, Graham D. Hamblin, Gonzalo Cosa, Hanadi F. Sleiman
Publikováno v:
ACS Nano. 7:3022-3028
DNA nanotubes have great potential as nanoscale scaffolds for the organization of materials and the templation of nanowires and as drug delivery vehicles. Current methods for making DNA nanotubes either rely on a tile-based step-growth polymerization
Publikováno v:
Current opinion in chemical biology. 36
Cells alter the proteome to respond to environmental and developmental cues. Global analysis of proteomic responses is of limited value in heterogeneous environments, where there is no ‘average’ cell. Advances in sequencing, protein labeling, mas