Zobrazeno 1 - 10
of 920
pro vyhledávání: '"D. Greenspan"'
Autor:
Mitchell Scheiman, Jacqueline Theis, Angela M Chen, Allegra P Burgher, Lynn D Greenspan, Andrew Morgenstern, Aaron D Salzano, Tiong Peng Yap, Tawna L Roberts
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Ocular motor function is susceptible to neurological injury because it requires a large portion of brain circuitry including every lobe of the brain, brainstem, thalamus, basal ganglia, cerebellum, cranial nerves and visual tracts. While
Externí odkaz:
https://doaj.org/article/0c9327cbaaff43b49404618bcd113a52
Autor:
Timothy J. Meeker, Anne-Christine Schmid, Michael L. Keaser, Shariq A. Khan, Rao P. Gullapalli, Susan G. Dorsey, Joel D. Greenspan, David A. Seminowicz
Publikováno v:
NeuroImage, Vol 256, Iss , Pp 119278- (2022)
Introduction: Resting state functional connectivity (FC) is widely used to assess functional brain alterations in patients with chronic pain. However, reports of FC accompanying tonic pain in pain-free persons are rare. A network we term the Descendi
Externí odkaz:
https://doaj.org/article/9ab7c9da79ed46b5bd922c7a70052bec
Autor:
Dieuwke S. Veldhuijzen, Timothy J. Meeker, Deborah Bauer, Michael L. Keaser, Rao P. Gullapalli, Joel D. Greenspan
Publikováno v:
Brain and Behavior, Vol 12, Iss 6, Pp n/a-n/a (2022)
Abstract Introduction Bidirectional effects between cognition and pain have been extensively reported. Although brain regions involved in cognitive and pain processing seem to partly overlap, it is unknown what specific brain regions are involved in
Externí odkaz:
https://doaj.org/article/5c3f4ab364d04db686f9ecf108b4314e
Autor:
Timothy J. Meeker, Dieuwke S. Veldhuijzen, Michael L. Keaser, Rao P. Gullapalli, Joel D. Greenspan
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The role of gonadal hormones in neural plasticity remains unclear. This study aimed to examine the effects of naturally fluctuating hormone levels over the menstrual cycle in healthy females. Gray matter, functional connectivity (FC) and white matter
Externí odkaz:
https://doaj.org/article/33059ae8839444c2bdba69466f3844db
Autor:
Marc Parisien, Samar Khoury, Anne-Julie Chabot-Doré, Susana G. Sotocinal, Gary D. Slade, Shad B. Smith, Roger B. Fillingim, Richard Ohrbach, Joel D. Greenspan, William Maixner, Jeffrey S. Mogil, Inna Belfer, Luda Diatchenko
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1940-1952 (2017)
Dorsal root ganglia (DRG) relay sensory information to the brain, giving rise to the perception of pain, disorders of which are prevalent and burdensome. Here, we mapped expression quantitative trait loci (eQTLs) in a collection of human DRGs. DRG eQ
Externí odkaz:
https://doaj.org/article/3a6588954ecc4835a5e89cb2f02df82b
Autor:
Gary D. Slade, Jonathan D. Rosen, Richard Ohrbach, Joel D. Greenspan, Roger B. Fillingim, Marc Parisien, Samar Khoury, Luda Diatchenko, William Maixner, Eric Bair
Publikováno v:
PAIN Reports, Vol 4, Iss 3, p e729 (2019)
Abstract. Background:. Chronic facial pain often overlaps with pain experienced elsewhere in the body, although previous studies have focused on a few, selected pain conditions when assessing the degree of overlap. Aim:. To quantify the degree of ove
Externí odkaz:
https://doaj.org/article/2b6185e8920a4266b6dbe9a5224279e9
Autor:
Timothy J. Meeker, Michael L. Keaser, Shariq A. Khan, Rao P. Gullapalli, David A. Seminowicz, Joel D. Greenspan
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Central sensitization is a driving mechanism in many chronic pain patients, and manifests as hyperalgesia and allodynia beyond any apparent injury. Recent studies have demonstrated analgesic effects of motor cortex (M1) stimulation in several chronic
Externí odkaz:
https://doaj.org/article/10e548cd1e954dbabbfda1fedc6b3196
Autor:
Hee Jun Kim, Joel D Greenspan, Richard Ohrbach, Roger B Fillingim, William Maixner, Cynthia L Renn, Meg Johantgen, Shijun Zhu, Susan G Dorsey
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215534 (2019)
This study evaluated the contributions of psychological status and cardiovascular responsiveness to racial/ethnic differences in experimental pain sensitivity. The baseline measures of 3,159 healthy individuals-non-Hispanic white (NHW): 1,637, Africa
Externí odkaz:
https://doaj.org/article/f472a8ac54e54ddb88c5389f7ec58d37
Publikováno v:
NeuroImage: Clinical, Vol 5, Iss C, Pp 309-321 (2014)
As the practice of conducting longitudinal fMRI studies to assess mechanisms of pain-reducing interventions becomes more common, there is a great need to assess the test–retest reliability of the pain-related BOLD fMRI signal across repeated sessio
Externí odkaz:
https://doaj.org/article/91a34e4c9ff74ee298f297124e88435a
Autor:
Alexandra E. Gould, Courtney Cullis, Lee Hong Myung, David Lok, Rachel E. Gershman, Scott R. Rowland, Miho Mizutani, Dave Janowick, Gipson Krista E, Vihren Kolev, Robert J. Griffin, Joe Conlon, Steve Stroud, Akito Hata, Jeffrey Ciavarri, Dylan Bradley England, Cardin David P, Sandeep Pusalkar, Paul D. Greenspan, Adnan O Abu-Yousif, Jenna Malley, Doanh Mai, Michael Shaw, Ji Zhang, Robert J. Skene, Hu Zhigen, Matthew A. Jones, Atsushi Matsuda, Shih-Chung Huang, Nina Molchanova, Xu Tianlin, Jian Huang, He Xu, Stepan Vyskocil, Nanda Gulavita, Francois Soucy, Gang Li, Yongbo Hu, Liting Ma, Steven P. Langston, Zhan Shi, Christelle C. Renou, Luhua Shen, Sean Harrison, Elise Nunes, Kenneth M. Gigstad, Yosuke Sato, Hirotake Mizutani
Publikováno v:
Journal of Medicinal Chemistry. 64:6902-6923
Stimulator of Interferon Genes (STING) plays an important role in innate immunity by inducing type I interferon production upon infection with intracellular pathogens. STING activation can promote increased T-cell activation and inflammation in the t