Zobrazeno 1 - 10
of 52
pro vyhledávání: '"D. Gouy"'
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 334:1-7
The cytochalasin B micronucleus test was performed in human peripheral lymphocyte cultures to assay the ability of hydroquinone and chloral hydrate to induce micronuclei, in the presence or absence of an exogenous metabolic activation system. Culture
Autor:
Y. Berger, G. Kieffer, Jean-Pierre Maffrand, G. Defreyn, E. Vallee, Jean-Marc Herbert, J. Necciari, D. Gouy, D. Frehel
Publikováno v:
Cardiovascular Drug Reviews. 11:180-198
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 291:93-102
The in vitro micronucleus test was performed on isolated human lymphocytes using the cytokinesis-block technique with and without a rat liver metabolizing system. Positive control substances were used to evaluate this test: a direct agent (vincristin
Autor:
B. Verschuere, J.-G. Passagia, N. Rajaofetra, L. Marlier, Alain Privat, Michel Geffard, F. Pellas, P. Poulat, F. Sandillon, D. Gouy
Publikováno v:
The Journal of Comparative Neurology. 318:1-17
We have investigated with light and electron microscope immunocytochemistry the aminergic and peptidergic innervation of Onuf's nucleus in adult baboons. This nucleus, located in the ventrolateral part of the sacral spinal cord (S2 and S3), is consid
Autor:
F. Sandillon, F. Famose, P. Poulat, Alain Privat, Marie-Jeanne Drian, N. Rajaofetra, Michel Geffard, B. Verschuere, Norbert König, L. Marlier, D. Gouy
Publikováno v:
Brain research. 572(1-2)
Five adult monkeys(Macaca fascicularis) underwent a total section of the spinal cord at the thoracic level (T6). Four of them received a daily treatment with cyclosporin (10 mg/kg). Ten days later, two animals treated with cyclosporin and one wiithou
Publikováno v:
Toxicology and applied pharmacology. 106(3)
Primary cultures of rat and human hepatocytes were used in our in vitro studies for investigating species differences in the response to a peroxisome proliferating benzofuran derivative, benzbromarone. Cyanide-insensitive palmitoyl coenzyme A oxidati
Publikováno v:
Pathologie-biologie. 38(3)
Primates are more and more frequently used in the evaluation of the safety aspects of drugs. Because of their similar phylogenic profile, these animals appear to be more predictive than other species (rat, mouse, rabbit or dog) used in toxicological
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 271:161
Publikováno v:
Annals of the New York Academy of Sciences. 407:374-386
Publikováno v:
Fundamental and Applied Toxicology. 4:152-163
Six benzodiazepine tranquilizers were tested in limited in vivo bioassays for their ability to initiate or promote the development of preneoplastic and neoplastic rat liver lesions. The benzodiazepine produced no liver altered hepatocellular foci dur