Zobrazeno 1 - 10
of 207
pro vyhledávání: '"D. Gourdji"'
Autor:
Paul Cohen, Véronique Carrière, Laurent Jonet, Jean-Claude Jeanny, Christophe Piesse, Thierry Foulon, Cécile Gouzy-Darmon, D. Gourdji, Didier Goidin, Sandrine Cadel
Publikováno v:
Experimental Eye Research. 79:639-648
Aminopeptidase B (Ap-B), a ubiquitous enzyme, catalyses the amino-terminal cleavage of basic residues of peptide or protein substrates, indicating a role in precursor processing. The physiological function of Ap-B still remains an open question, even
Publikováno v:
Journal of Neuroendocrinology. 15:592-601
A cDNA membrane array displaying 1183 probes was used to detect hypothalamic and pituitary changes in gene expression accompanying ageing and age-associated pituitary macroadenomas. Four groups of male Sprague-Dawley rats (3-, 15-, 24-month-old and 2
Autor:
Annette Hus-Citharel, Dominique Chansel, Catherine Llorens-Cortes, D. Gourdji, Jeannine Marchetti, D. Goidin, Pierre Corvol, Nadine Bouby
Publikováno v:
Endocrinology. 142:4683-4692
Differences involving serine residues in the sequence of the carboxyl-terminal tail of type 1 angiotensin II (Ang II) receptor subtypes AT(1A) and AT(1B) suggest differences in desensitization ability. We examined the Ang II-induced homologous desens
Publikováno v:
Endocrinology. 141:4805-4808
Aging of the rat pituitary is often accompanied by the occurrence of adenomas. We asked whether complementary DNA hybridization array was adapted to identify gene expression patterns linked to aging and associated spontaneous adenomas. Thus, [32P]dAT
Autor:
Claude Kordon, M. Priam, D. Gourdji, Dragan Djordjijevic, Jacques Epelbaum, Ji Zhang, Cécile Viollet
Publikováno v:
Endocrinology. 139:2272-2277
In the present study, we tested whether 17beta-estradiol (E2)-induced PRL sensitivity to somatostatin-14 (SRIF) involves selective up-regulation of discrete somatostatin receptor subtypes (ssts) in primary cultures of female rat pituitary cells. The
Publikováno v:
Cellular and Molecular Neurobiology. 18:101-123
1. Regulation of pulsatile secretion of growth hormone (GH) relies on hypothalamic neuronal loops, major transmitters involved in their operation are growth hormone releasing hormone (GHRH) synthetized mostly in arcuate nucleus (ARC) neurons, and som
Publikováno v:
Molecular and Cellular Biology. 16:3245-3254
The methylation patterns of the rat prolactin (rPRL) (positions -440 to -20) and growth hormone (rGH) (positions -360 to -110) promoters were analyzed by bisulfite genomic sequencing. Two normal tissues, the anterior pituitary and the liver, and thre
Publikováno v:
Molecular and Cellular Endocrinology. 107:29-40
In mammosomatotropes GH3B6 cells, one of the primary responses to thyrotropin-releasing hormone (TRH) is the parallel induction of two proto-oncogenes, c-fos and jun B, which code for constituents of AP1 transcription factor. To better understand the
Publikováno v:
Molecular and Cellular Neuroscience. 5:109-118
The hypothalamic neuropeptide TRH stimulates PRL release and PRL gene transcription in GH3B6 rat pituitary cells. In this model, TRH also raises c-fos proto-oncogene mRNA levels. c-fos is assumed to be involved in the transduction of external signals
Autor:
Pierre-André Cazenave, Andrée Tixier-Vidal, D. Gourdji, Philippe Denoulet, Dominique Grouselle, Annie Rousselet, Jacques Roland
Publikováno v:
Neuroendocrinology. 59:495-504
cDNA encoding the thyrotropin-releasing hormone receptor (TRH-R) was recently cloned in rat pituitary prolactin cells and in mouse thyrotropes. The molecular weights of the protein sequences obtained are 46.6 and 44.5 kD. However, TRH-R has not yet b