Zobrazeno 1 - 10
of 88
pro vyhledávání: '"D. Gonzalez de Castro"'
Autor:
G. M. Walls, L. McConnell, J. McAleese, P. Murray, T. B. Lynch, K. Savage, G. G. Hanna, D. Gonzalez de Castro
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduced patient risk and t
Externí odkaz:
https://doaj.org/article/67e187b461644439a16c2de4d8966fa9
Akademický článek
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Autor:
A Ervine, D Gonzalez de Castro, C Boyd, I Cameron, T Harita, Colin McIlmunn, Deirdre Fitzpatrick, Finian Bannon, Stuart McIntosh, Jacqueline James, Kienan Savage
Publikováno v:
Cancer Research. 79:P1-09
Contralateral breast cancer (CBC) incidence is reported as 0.4-0.7% per year, equating to an approximate 10-15% 20 year risk after primary cancer diagnosis. Young age at primary diagnosis and a strong family history are consistently cited as signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4850886a864d19cc23f0a6b6d725af5
https://doi.org/10.1158/1538-7445.sabcs18-p1-09-10
https://doi.org/10.1158/1538-7445.sabcs18-p1-09-10
Autor:
P. Murray, D. Gonzalez de Castro, T. Lynch, Kienan Savage, Gerard Walls, Gerard G Hanna, J. McAleese, L. McConnell
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-9 (2020)
Radiation Oncology (London, England)
Walls, G M, McConnell, L, McAleese, J, Murray, P, Lynch, T B, Savage, K, Hanna, G G & de Castro, D G 2020, ' Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study ', Radiation oncology (London, England), vol. 15, no. 1, pp. 132 . https://doi.org/10.1186/s13014-020-01583-7
Radiation Oncology (London, England)
Walls, G M, McConnell, L, McAleese, J, Murray, P, Lynch, T B, Savage, K, Hanna, G G & de Castro, D G 2020, ' Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study ', Radiation oncology (London, England), vol. 15, no. 1, pp. 132 . https://doi.org/10.1186/s13014-020-01583-7
Background The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduced patient risk and the opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d283d5d393079842faec8eb59edffb
https://doi.org/10.1186/s13014-020-01583-7
https://doi.org/10.1186/s13014-020-01583-7
Autor:
Matthew Frampton, Nicola Valeri, Naureen Starling, D. Gonzalez de Castro, Avni Patel, Brian A Walker, Lina Yuan, Angela Gillbanks, Chiara Baratelli, Sheela Rao, Marco Gerlinger, David Cunningham, Clare Peckitt, L S Teixeira Mendes, David Watkins, A C Wotherspoon, Ruwaida Begum, Thomas Jones, N. Fotiadis, Sing Yu Moorcraft, Zakaria Eltahir, S. Hulkki Wilson, Ian Chau, Chiara Braconi
Publikováno v:
Annals of Oncology. 29:230-236
Background Targeted capture sequencing can potentially facilitate precision medicine, but the feasibility of this approach in gastrointestinal (GI) malignancies is unknown. Patients and methods The FOrMAT (Feasibility of a Molecular Characterisation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601b06333d8d850f86d282767aefdd9c
https://doi.org/10.1093/annonc/mdx631
https://doi.org/10.1093/annonc/mdx631
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
A C Wotherspoon, Andrés Cervantes, Jens C. Hahne, Zakaria Eltahir, Clare Peckitt, D. Gonzalez de Castro, S. Hulkki Wilson, Diana Tait, Ruwaida Begum, Andrea Lampis, Ian Chau, Francesco Sclafani, Nicola Valeri, Chiara Braconi, Gina Brown, Jacqui Oates, David Cunningham, Bengt Glimelius, Josep Tabernero
Publikováno v:
Annals of Oncology
Sclafani, F, Chau, I, Cunningham, D, Peckitt, C, Lampis, A, Hahne, J C, Braconi, C, Tabernero, J, Glimelius, B, Cervantes, A, Begum, R, Gonzalez De Castro, D, Hulkki Wilson, S, Eltahir, Z, Wotherspoon, A, Tait, D, Brown, G, Oates, J & Valeri, N 2015, ' Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial. ', Annals of Oncology, vol. 26, no. 9, pp. 1936-1941 . https://doi.org/10.1093/annonc/mdv285
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Sclafani, F, Chau, I, Cunningham, D, Peckitt, C, Lampis, A, Hahne, J C, Braconi, C, Tabernero, J, Glimelius, B, Cervantes, A, Begum, R, Gonzalez De Castro, D, Hulkki Wilson, S, Eltahir, Z, Wotherspoon, A, Tait, D, Brown, G, Oates, J & Valeri, N 2015, ' Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial. ', Annals of Oncology, vol. 26, no. 9, pp. 1936-1941 . https://doi.org/10.1093/annonc/mdv285
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
KRAS mutation has been reported as a marker of radio-resistance in rectal cancer and unfavourable outcome in both colon and rectal cancer. This study suggests that a single-nucleotide polymorphism of the KRAS gene (LCS-6 variant) may predict response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8366e7c40f379f312048d0d57b87f716
https://doi.org/10.1093/annonc/mdv285
https://doi.org/10.1093/annonc/mdv285
Autor:
Tatjana Stankovic, Christopher Fegan, David G. Oscier, Kevin Norris, JC Strefford, Chris Pepper, D. Gonzalez de Castro, Monica Else, Matthew J. J. Rose-Zerilli, Nicole H. Heppel, Duncan M. Baird, Anne Gardiner, Zadie A. Davies, Thet Thet Lin, Andrew J. Steele, Helen Parker, Jade Forster, A. Parker, Latha Kadalayil, Andrew Collins, Daniel Catovsky
Publikováno v:
Leukemia
Telomere erosion and fusion play an important role in the pathology of many common human malignancies including CLL.1,2 Previous studies in CLL have shown that short telomeres defined on the basis of the median value or receiver operating characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8bb6cf5705a4aa65d3e38b7207e352
https://doi.org/10.1038/leu.2015.217
https://doi.org/10.1038/leu.2015.217
Autor:
Phil Quirke, Nicholas P. West, S. Hulkki Wilson, Simon Gollins, Sandy Beare, Kyriakos Kouvelakis, L. Hughes, Francesco Sclafani, Ian Chau, D. Gonzalez de Castro, David Cunningham, Andre Lopes, Nicola Valeri, Ruwaida Begum
Publikováno v:
Annals of Oncology. 28:x55-x56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c425d8258685d76b41e0dd1cd423c897
https://doi.org/10.1093/annonc/mdx659.046
https://doi.org/10.1093/annonc/mdx659.046