Zobrazeno 1 - 10
of 569
pro vyhledávání: '"D. Givol"'
Publikováno v:
The Journal of Immunology. 144:2620-2626
The reactivity of 23 mouse monoclonal Ig with a rabbit polyclonal antiserum to VH of anti-alpha(1----6)dextran 19.22.1 and with a monoclonal anti-VH of anti-DNP MOPC315, when correlated with amino acid sequence, identified several residues in the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7388873c9a0b070290d053b374f395a
https://doi.org/10.4049/jimmunol.144.7.2620
https://doi.org/10.4049/jimmunol.144.7.2620
The p53-regulated p21Waf1 protein is a universal inhibitor of cyclin-dependent kinases (CDKs). To study the potential tumor-suppressive properties of CDK inhibitors, the ability of p21Waf1 to interfere with oncogene-mediated cellular transformation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e521f7a3846505c790bac46d34dad01e
http://hdl.handle.net/2318/149421
http://hdl.handle.net/2318/149421
Publikováno v:
Oncogene. 11(12)
In normal cells, cell growth and division is controlled by the interplay between proto-oncogenes and tumor suppressor genes. Cancer cells usually have both activated an oncogene and have lost a functional tumor suppressor gene. High level expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::725d973c270c109abf9a376722357250
https://pubmed.ncbi.nlm.nih.gov/8545118
https://pubmed.ncbi.nlm.nih.gov/8545118
Publikováno v:
Oncogene. 8(8)
Previous studies in vivo and in vitro show that KIT kinase promotes normal melanocyte development and growth. However, the role of the KIT proto-oncogene in neoplastic melanocytes is not certain. We therefore examined KIT expression and function in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::290840ac2c4411a451ec309f240b8261
https://pubmed.ncbi.nlm.nih.gov/7687762
https://pubmed.ncbi.nlm.nih.gov/7687762
Publikováno v:
The Journal of biological chemistry. 268(6)
The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. The extracellular domain of p145kit consists of fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::539285ab50b72fb030eb58edc57fb6eb
https://pubmed.ncbi.nlm.nih.gov/7680037
https://pubmed.ncbi.nlm.nih.gov/7680037
Publikováno v:
Oncogene. 7(10)
Fibroblast growth factors (FGFs) and their receptors play an important role in cell growth, angiogenesis and embryonal development. Four distinct genes encoding fibroblast growth factor receptors (FGFRs) were identified: flg, encoding FGFR1, bek enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55816663f97bc7e150cfc3c140efc7da
https://pubmed.ncbi.nlm.nih.gov/1408137
https://pubmed.ncbi.nlm.nih.gov/1408137
Publikováno v:
Oncogene. 7(7)
The murine Kit receptor gene on chromosome 5 has been found to be frequently involved in germline mutations and rearrangements, leading to a characteristic set of severe developmental defects, known as the W phenotype. Here we describe the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8ad14b4d182ac62cadbda3f916acf51
https://pubmed.ncbi.nlm.nih.gov/1377813
https://pubmed.ncbi.nlm.nih.gov/1377813
Publikováno v:
Oncogene. 6(6)
Two genes, flg and bek, have been recently shown to encode receptors for fibroblast growth factors (FGF). Here we report the molecular cloning and sequence of a new member of the FGF receptor family, denoted flg-2, which was isolated from a human ker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cd8fba1d22aa5b63492018c8ed6159e
https://pubmed.ncbi.nlm.nih.gov/1648703
https://pubmed.ncbi.nlm.nih.gov/1648703
Publikováno v:
Oncogene. 6(5)
Transmembrane tyrosine kinases are involved in the control of cell growth and differentiation by extracellular signals. To enable identification of new receptor tyrosine kinases we developed a method that selectively amplifies segments of receptor ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e38907fbdaef04d753f69699952250f8
https://pubmed.ncbi.nlm.nih.gov/1711190
https://pubmed.ncbi.nlm.nih.gov/1711190
Publikováno v:
Oncogene. 6(4)
While murine and human EGF-receptor (EGF-R) bind mammalian EGF with high affinity their chicken counterpart has approximately 300 fold reduced binding affinity towards mammalian EGF. We now cloned and sequenced the extracellular ligand binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c67723d2fe7b53b39f8e1a5615bef6d2
https://pubmed.ncbi.nlm.nih.gov/2030916
https://pubmed.ncbi.nlm.nih.gov/2030916