Zobrazeno 1 - 10
of 1 011
pro vyhledávání: '"D. Ginsberg"'
Autor:
Melissa J. Alldred, Kyrillos W. Ibrahim, Harshitha Pidikiti, Gabriela Chiosis, Elliott J. Mufson, Grace E. Stutzmann, Stephen D. Ginsberg
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Selective vulnerability of neuronal populations occurs in both Down syndrome (DS) and Alzheimer’s disease (AD), resulting in disproportional degeneration of pyramidal neurons (PNs) affecting memory and executive function. Elucidating the c
Externí odkaz:
https://doaj.org/article/348597d6553b4ec5978cc74dd3d4a01c
Autor:
Tanaya Roychowdhury, Seth W. McNutt, Chiranjeevi Pasala, Hieu T. Nguyen, Daniel T. Thornton, Sahil Sharma, Luke Botticelli, Chander S. Digwal, Suhasini Joshi, Nan Yang, Palak Panchal, Souparna Chakrabarty, Sadik Bay, Vladimir Markov, Charlene Kwong, Jeanine Lisanti, Sun Young Chung, Stephen D. Ginsberg, Pengrong Yan, Elisa De Stanchina, Adriana Corben, Shanu Modi, Mary L. Alpaugh, Giorgio Colombo, Hediye Erdjument-Bromage, Thomas A. Neubert, Robert J. Chalkley, Peter R. Baker, Alma L. Burlingame, Anna Rodina, Gabriela Chiosis, Feixia Chu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-28 (2024)
Abstract The intricate network of protein-chaperone interactions is crucial for maintaining cellular function. Recent discoveries have unveiled the existence of specialized chaperone assemblies, known as epichaperomes, which serve as scaffolding plat
Externí odkaz:
https://doaj.org/article/2f7ed5a1fa2f46d69f151277d59c0181
Autor:
Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, Sylvia Perez, Bin He, Stephen D. Ginsberg, Michael Mullan, Elliott J. Mufson, Fiona Crawford, Joseph Ojo
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Epidemiological studies have unveiled a robust link between exposure to repetitive mild traumatic brain injury (r-mTBI) and elevated susceptibility to develop neurodegenerative disorders, notably chronic traumatic encephalopathy (CTE). The p
Externí odkaz:
https://doaj.org/article/812260dbcf494e8a958de716a1f01242
Autor:
Elissavet Chartampila, Karim S Elayouby, Paige Leary, John J LaFrancois, David Alcantara-Gonzalez, Swati Jain, Kasey Gerencer, Justin J Botterill, Stephen D Ginsberg, Helen E Scharfman
Publikováno v:
eLife, Vol 12 (2024)
Maternal choline supplementation (MCS) improves cognition in Alzheimer’s disease (AD) models. However, the effects of MCS on neuronal hyperexcitability in AD are unknown. We investigated the effects of MCS in a well-established mouse model of AD wi
Externí odkaz:
https://doaj.org/article/0e246cdcf3d74bf2920d9ad020418a20
Autor:
Anna Rodina, Chao Xu, Chander S. Digwal, Suhasini Joshi, Yogita Patel, Anand R. Santhaseela, Sadik Bay, Swathi Merugu, Aftab Alam, Pengrong Yan, Chenghua Yang, Tanaya Roychowdhury, Palak Panchal, Liza Shrestha, Yanlong Kang, Sahil Sharma, Justina Almodovar, Adriana Corben, Mary L. Alpaugh, Shanu Modi, Monica L. Guzman, Teng Fei, Tony Taldone, Stephen D. Ginsberg, Hediye Erdjument-Bromage, Thomas A. Neubert, Katia Manova-Todorova, Meng-Fu Bryan Tsou, Jason C. Young, Tai Wang, Gabriela Chiosis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Systems-level assessments of protein-protein interaction (PPI) network dysfunctions are currently out-of-reach because approaches enabling proteome-wide identification, analysis, and modulation of context-specific PPI changes in native (unen
Externí odkaz:
https://doaj.org/article/bd99358101954a8492861b762bbf8146
Autor:
Sadik Bay, Chander S. Digwal, Ananda M. Rodilla Martín, Sahil Sharma, Aleksandra Stanisavljevic, Anna Rodina, Anoosha Attaran, Tanaya Roychowdhury, Kamya Parikh, Eugene Toth, Palak Panchal, Eric Rosiek, Chiranjeevi Pasala, Ottavio Arancio, Paul E. Fraser, Melissa J. Alldred, Marco A. M. Prado, Stephen D. Ginsberg, Gabriela Chiosis
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1252 (2024)
Neurodegenerative disorders, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), represent debilitating conditions with complex, poorly understood pathologies. Epichaperomes, pathologic protein assemblies nucleated on key chaperones,
Externí odkaz:
https://doaj.org/article/4dbcf551145247a7b517292e9d2527fa
Autor:
Michael Malek-Ahmadi, Stephen D. Ginsberg, Melissa J. Alldred, Scott E. Counts, Milos D. Ikonomovic, Eric E. Abrahamson, Sylvia E. Perez, Elliott J. Mufson
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2024)
Linear regression is one of the most used statistical techniques in neuroscience, including the study of the neuropathology of Alzheimer’s disease (AD) dementia. However, the practical utility of this approach is often limited because dependent var
Externí odkaz:
https://doaj.org/article/9e57cd328e6e4de094dc34a92b3189d8
Autor:
E Kreydin, V Montero Arcila, L Morales Ojeda, D Chapman, R Jen, P Kohli, S Ponce, N Ha, D Ginsberg, V Edgerton, P Gad, K Jann, A Abedi
Publikováno v:
Continence, Vol 7, Iss , Pp 100949- (2023)
Externí odkaz:
https://doaj.org/article/95849f6db5444fa195e1acc2ccde6dc6
Autor:
E Enemchukwu, E Rovner, L Birder, C Chermansky, R Dmochowski, D Ginsberg, S Menefee, G Nadeau, C Rardin, P Zimmern
Publikováno v:
Continence, Vol 7, Iss , Pp 100724- (2023)
Externí odkaz:
https://doaj.org/article/2cf16e29d7924914926b5198b83448e9
Autor:
E Kreydin, V Montero Arcila, L Morales Ojeda, D Chapman, P Kohli, N Ha, R Jen, S Ponce, V Edgerton, P Gad, D Ginsberg, K Jann, A Abedi
Publikováno v:
Continence, Vol 7, Iss , Pp 100760- (2023)
Externí odkaz:
https://doaj.org/article/39965586c2ce4ab498c58e1f9e79eff4