Zobrazeno 1 - 10
of 761
pro vyhledávání: '"D. Gilmore"'
Publikováno v:
Ticks and Tick-Borne Diseases, Vol 15, Iss 3, Pp 102324- (2024)
A Borrelia miyamotoi gene with partial homology to bipA of relapsing fever spirochetes Borrelia hermsii and Borrelia turicatae was identified by a GenBank basic alignment search analysis. We hypothesized that this gene product may be an immunogenic a
Externí odkaz:
https://doaj.org/article/856fb378fb4e4598b7d84566c511c187
Autor:
Pablo J. Aguirre Carrión, Niharika Desai, Joseph J. Brennan, James E. Fifer, Trevor Siggers, Sarah W. Davies, Thomas D. Gilmore
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Lack of proper nutrition has important consequences for the physiology of all organisms, and nutritional status can affect immunity, based on many studies in terrestrial animals. Here we show a positive correlation between nutrition and immu
Externí odkaz:
https://doaj.org/article/b3f4a93af5f44cb2b86fd869aa3679e2
Autor:
Michael J. Rudolph, Simon A. Davis, H. M. Emranul Haque, David D. Weis, David J. Vance, Carol Lyn Piazza, Monir Ejemel, Lisa Cavacini, Yang Wang, M. Lamine Mbow, Robert D. Gilmore, Nicholas J. Mantis
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Outer surface protein C (OspC) plays a pivotal role in mediating tick-to-host transmission and infectivity of the Lyme disease spirochete, Borreliella burgdorferi. OspC is a helical-rich homodimer that interacts with tick salivary proteins,
Externí odkaz:
https://doaj.org/article/c08808c46b244cddb14dfe929eef3a85
Autor:
Robert D Gilmore, Brittany A Armstrong, Kevin S Brandt, Taylor J Van Gundy, Andrias Hojgaard, Job E Lopez, Alexander R Kneubehl
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281942 (2023)
Borrelia miyamotoi is a tick-transmitted spirochete that is genetically grouped with relapsing fever Borrelia and possesses multiple archived pseudogenes that encode variable major proteins (Vmps). Vmps are divided into two groups based on molecular
Externí odkaz:
https://doaj.org/article/78a03aaa769d4a8fa09aaf4d3ea827ad
Autor:
Leah M. Williams, Sainetra Sridhar, Jason Samaroo, Jada Peart, Ebubechi K. Adindu, Anvitha Addanki, Christopher J. DiRusso, BB522 Molecular Biology Laboratory, Pablo J. Aguirre Carrión, Nahomie Rodriguez-Sastre, Trevor Siggers, Thomas D. Gilmore
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Transcription factor NF-ĸB is a key regulator of immunity in mammals, but its function in protists like Capsaspora and choanoflagellates is not known. Here, Leah Williams et al. characterize and compare the structure, activity, and regulation of NF-
Externí odkaz:
https://doaj.org/article/a43d1a02e3784cfb97982cdcc7351ace
Autor:
Leah M. Williams, Thomas D. Gilmore
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10 (2022)
Homologs of mammalian innate immune sensing and downstream pathway proteins have been discovered in a variety of basal invertebrates, including cnidarians and sponges, as well as some single-celled protists. Although the structures of these proteins
Externí odkaz:
https://doaj.org/article/42061f4848ed49529d5160384110927e
Publikováno v:
Brain Informatics, Vol 8, Iss 1, Pp 1-15 (2021)
Abstract Subject motion can introduce noise into neuroimaging data and result in biased estimations of brain structure. In-scanner motion can compromise data quality in a number of ways and varies widely across developmental and clinical populations.
Externí odkaz:
https://doaj.org/article/260ec95d20bc49d2b1be86a522b178f7
Autor:
Shannon D. Donofry, Alina Lesnovskaya, Jermon A. Drake, Hayley S. Ripperger, Alysha D. Gilmore, Patrick T. Donahue, Mary E. Crisafio, George Grove, Amanda L. Gentry, Susan M. Sereika, Catherine M. Bender, Kirk I. Erickson
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
ObjectiveOverweight and obesity [body mass index (BMI) ≥ 25 kg/m2] are associated with poorer prognosis among women with breast cancer, and weight gain is common during treatment. Symptoms of depression and anxiety are also highly prevalent in wome
Externí odkaz:
https://doaj.org/article/e71e4931dcfb480dbd28e5349fabb5a9
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Serologic testing is the standard for laboratory diagnosis and confirmation of Lyme disease. Serodiagnostic assays to detect antibodies against Borrelia burgdorferi, the agent of Lyme borreliosis, are used for detection of infection. However, serolog
Externí odkaz:
https://doaj.org/article/1ce2cce7e2e24e3baac1f9a190a4b14b
Autor:
Thomas D. Gilmore
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 889 (2021)
Transcription factor NF-κB has been extensively studied for its varied roles in cancer development since its initial characterization as a potent retroviral oncogene. It is now clear that NF-κB also plays a major role in a large variety of human ca
Externí odkaz:
https://doaj.org/article/e6c0b7d990324e518bcaff3adfbd4365