Zobrazeno 1 - 10
of 429
pro vyhledávání: '"D. Garland"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286741 (2023)
Most of the small-molecule drugs approved for the treatment of cancer over the past 40 years are based on natural compounds. Bacteria provide an extensive reservoir for the development of further anti-cancer therapeutics to meet the challenges posed
Externí odkaz:
https://doaj.org/article/fdacae6b13064ec4936ff0bd3ed84753
Autor:
Stefano Grosso, Alberto Marini, Katarina Gyuraszova, Johan Vande Voorde, Aristeidis Sfakianos, Gavin D. Garland, Angela Rubio Tenor, Ryan Mordue, Tanya Chernova, Nobu Morone, Marco Sereno, Claire P. Smith, Leah Officer, Pooyeh Farahmand, Claire Rooney, David Sumpton, Madhumita Das, Ana Teodósio, Catherine Ficken, Maria Guerra Martin, Ruth V. Spriggs, Xiao-Ming Sun, Martin Bushell, Owen J. Sansom, Daniel Murphy, Marion MacFarlane, John P. C. Le Quesne, Anne E. Willis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Treating malignant pleural mesothelioma (MpM) is challenging due to a lack of druggable genes, but other molecular features could be clinically useful. Here the authors profile mRNA translation dysregulation in MpM cell lines using polysome profiling
Externí odkaz:
https://doaj.org/article/7e118ded480445418fbb52706c703037
Autor:
Cristian A. Robbins, Brandi M. Grauberger, Shane D. Garland, Kenneth H. Carlson, Shihong Lin, Todd M. Bandhauer, Tiezheng Tong
Publikováno v:
Environment International, Vol 145, Iss , Pp 106142- (2020)
Leveraging waste heat has been considered to have significant potential for promoting the economic feasibility of wastewater treatment in unconventional oil and gas (UOG) production. However, its availability near well sites has not been fully unders
Externí odkaz:
https://doaj.org/article/ffffe2da9d294091b27f8e1416d41d0a
Publikováno v:
Seminars in Cancer Biology. 86:151-165
In tumourigenesis, oncogenes or dysregulated tumour suppressor genes alter the canonical translation machinery leading to a reprogramming of the translatome that, in turn, promotes the translation of selected mRNAs encoding proteins involved in proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9488ab0192ff02da88a759dccd9d1c
https://doi.org/10.1016/j.semcancer.2022.04.006
https://doi.org/10.1016/j.semcancer.2022.04.006
Autor:
Gavin D. Garland, Robert F. Harvey, Thomas E. Mulroney, Mie Monti, Stewart Fuller, Richard Haigh, Pehuén Pereyra Gerber, Michael R. Barer, Nicholas J. Matheson, Anne E. Willis
Publikováno v:
Biochemical Journal. 479:901-920
Diagnostic testing continues to be an integral component of the strategy to contain the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) global pandemic, the causative agent of Coronavirus Disease 2019 (COVID-19). The SARS-CoV-2 genome en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c27707371511030a4a9585fe34feb0
https://doi.org/10.1042/bcj20220105
https://doi.org/10.1042/bcj20220105
Autor:
Melanie R. Hassler, Walter Pulverer, Ranjani Lakshminarasimhan, Elisa Redl, Julia Hacker, Gavin D. Garland, Olaf Merkel, Ana-Iris Schiefer, Ingrid Simonitsch-Klupp, Lukas Kenner, Daniel J. Weisenberger, Andreas Weinhaeusel, Suzanne D. Turner, Gerda Egger
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 596-608 (2016)
Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive (ALK+) and NPM-ALK-ne
Externí odkaz:
https://doaj.org/article/ac19a1ab1bff47b19952fae16e455e81
Akademický článek
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Autor:
Brandi M. Grauberger, Tiezheng Tong, Kenneth H. Carlson, Todd M. Bandhauer, Shane D. Garland, Cristian A. Robbins
Publikováno v:
ACS ES&T Engineering. 1:192-203
The effective treatment of unconventional oil and gas (UOG) wastewater is a promising and potentially necessary strategy of wastewater management in the UOG industry. While tremendous efforts have ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ea4931df460d6ee459e461ea94d52d
https://doi.org/10.1021/acsestengg.0c00049
https://doi.org/10.1021/acsestengg.0c00049
Autor:
Gavin D. Garland, Stephen P. Ducray, Leila Jahangiri, Perla Pucci, G. A. Amos Burke, Jack Monahan, Raymond Lai, Olaf Merkel, Ana-Iris Schiefer, Lukas Kenner, Andrew J. Bannister, Suzanne D. Turner
Publikováno v:
Cancers; Volume 14; Issue 1; Pages: 151
Cancers, Vol 14, Iss 151, p 151 (2022)
Cancers
Cancers, Vol 14, Iss 151, p 151 (2022)
Cancers
Simple Summary T-cell lymphoma is a cancer of the immune system. One specific sub-type of T-cell lymphoma is a malignancy called anaplastic large cell lymphoma (ALCL), which is distinct from the other forms, as in general, it has a better prognosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd815c4096169a0e2b74c229a852743
https://www.repository.cam.ac.uk/handle/1810/331950
https://www.repository.cam.ac.uk/handle/1810/331950
Autor:
Elliot J. Fuller, M. J. Marinella, François Léonard, S. R. Ellis, Bolin Liao, A. Alec Talin, J. R. Michael, D. R. Hughart, D. Garland, K. C. Celio, Norman C. Bartelt, David Chandler
Publikováno v:
Physical Review B. 104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404e7cc3ef744c706cdae14adaaee8ef
https://doi.org/10.1103/physrevb.104.l161303
https://doi.org/10.1103/physrevb.104.l161303