Zobrazeno 1 - 10
of 53
pro vyhledávání: '"D. Galendo"'
Publikováno v:
Oncogene. 26:3857-3867
The DNA strand break-binding molecule, poly(ADP-ribose) polymerase-1 (PARP-1), plays a role in DNA repair, chromosomal stability, transcription and cell death. Accumulating evidence suggests that dysfunction of PARP-1 contributes to tumorigenesis. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c5a1f5f527f5a7eb340578c5c0383
https://doi.org/10.1038/sj.onc.1210156
https://doi.org/10.1038/sj.onc.1210156
Publikováno v:
International Journal of Cancer. 119:745-749
Hepatocellular carcinoma (HCC) is a common human malignancy that is often associated with risk factors such as aflatoxin-B1 (AFB1) exposure and Hepatitis-B virus infection in developing countries. There is a strong correlation between these risk fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd4b0bd6a620d39057c7722252c90c2
https://doi.org/10.1002/ijc.21890
https://doi.org/10.1002/ijc.21890
The induction and persistence of altered sphingolipid biosynthesis in rats treated with fumonisin B1
Publikováno v:
Food Additives and Contaminants. 18:850-856
The fumonisins produced by Fusarium spp. are carcinogenic in rodents and possibly carcinogenic to humans. One action of fumonisins is to inhibit the enzyme ceramide synthase and as a consequence disrupt de novo sphingolipid biosynthesis. Measurement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf7bf054cf2c21390fa0e68dc5a5eab
https://doi.org/10.1080/02652030120881
https://doi.org/10.1080/02652030120881
The induction and persistence of altered sphingolipid biosynthesis in rats treated with fumonisin B1
Publikováno v:
Food Additives and Contaminants. 18:850-856
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4d5a1d255be05be0c08bdff0c89962
https://doi.org/10.1080/02652030110046910
https://doi.org/10.1080/02652030110046910
Autor:
Wentzel C. A. Gelderblom, Sonja Swanevelder, D. Galendo, W. F. O. Marasas, Christopher P. Wild, Stefan Abel
Publikováno v:
Cancer Letters. 169:127-137
Fumonisin B1 (FB1), a carcinogenic mycotoxin produced by the fungus Fusarium verticillioides in corn, causes cancer initiation in rat liver in a similar manner to genotoxic carcinogens although apparently with different kinetics. The present experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6400efdf05eca669b3cb9512d9cad6b3
https://doi.org/10.1016/s0304-3835(01)00542-0
https://doi.org/10.1016/s0304-3835(01)00542-0
Autor:
Hiroko Ohgaki, Marcel Castegnaro, Lillian Garren, D. Galendo, Christopher P. Wild, J. David Miller
Publikováno v:
Natural Toxins. 5:126-131
Fumonisins and N-nitrosamines (NNO) are suggested risk factors in the development of human oesophageal cancer; exposure to both occurs in high risk populations in Africa and People's Republic of China. The hypothesis that the two would interact in oe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d6c389b444f05051ce82430d047ebf
https://doi.org/10.1002/1522-7189(1997)5:3<126::aid-nt8>3.0.co
https://doi.org/10.1002/1522-7189(1997)5:3<126::aid-nt8>3.0.co
Autor:
Paul Kiprono Chelule, Michael F. Dutton, Wentzel C. A. Gelderblom, D. Galendo, Christopher P. Wild, L. Garren, Marcel Castegnaro
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 720:15-24
The toxins produced by Fusarium moniliforme, which include fumonisins, are possible human carcinogens. Fumonisins are inhibitors of de novo sphingolipid biosynthesis. Alterations of the ratio of sphinganine (Sa) to sphingosine (So) in urine and serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35633de8022d83a6c31741dc58a439cc
https://doi.org/10.1016/s0378-4347(98)00446-0
https://doi.org/10.1016/s0378-4347(98)00446-0
Publikováno v:
Cancer Letters. 49:147-152
The pesticide Deltamethrin, a synthetic pyrethroid, was studied for carcinogenicity in long-term experiments in mice and rats. Mice were given Deltamethrin by gavage in arachis oil at 0, 1, 4 or 8 mg/kg body wt for 2 years. A group of untreated contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d352a2a451436898791aa554f44132a5
https://doi.org/10.1016/0304-3835(90)90151-m
https://doi.org/10.1016/0304-3835(90)90151-m
Autor:
J. Ricardo P. Cabral, D. Galendo, Lorenzo Tomatis, Nicole Martel, Alexandre Loktionov, Monica Hollstein, Hiroshi Yamasaki
Publikováno v:
Molecular Carcinogenesis. 3:134-140
Transplacental carcinogenesis represents a good model in which to study the involvement of tissue-specific oncogene activation in carcinogenesis because a single exposure to a carcinogen induces tumors at various sites. We tested tumors of the skin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b70d8ae280056d4108cd4e9d7795f3
https://doi.org/10.1002/mc.2940030306
https://doi.org/10.1002/mc.2940030306
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 17(9)
Multiple endocrine neoplasia type 1 (MEN1) is a hereditary syndrome characterized by the occurrence of multiple endocrine tumors of the parathyroid, pancreas, and anterior pituitary in patients. To study tumorigenesis related to the MEN1 syndrome, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4752b1c74fd670eb4aa615e4f39b56
https://pubmed.ncbi.nlm.nih.gov/12819299
https://pubmed.ncbi.nlm.nih.gov/12819299