Zobrazeno 1 - 10
of 325
pro vyhledávání: '"D. G. EVANS"'
Publikováno v:
Weather and Climate Dynamics, Vol 5, Pp 109-132 (2024)
Amplified Arctic ice loss in recent decades has been linked to the increased occurrence of extreme mid-latitude weather. The underlying mechanisms remain elusive, however. One potential link occurs through the ocean as the loss of sea ice and glacial
Externí odkaz:
https://doaj.org/article/9eff1c3da8de47e2a6461b452e4d1b36
Autor:
A. Sanchez‐Franks, N. P. Holliday, D. G. Evans, N. Fried, O. Tooth, L. Chafik, Y. Fu, F. Li, M. F. deJong, H. L. Johnson
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 8, Pp n/a-n/a (2024)
Abstract The lower limb of the Atlantic meridional overturning circulation (AMOC) is the equatorward flow of dense waters formed through the cooling and freshening of the poleward‐flowing upper limb. In the subpolar North Atlantic (SPNA), upper lim
Externí odkaz:
https://doaj.org/article/b334a11282db45cb9ca0dac015fb9537
Publikováno v:
Ocean Science, Vol 19, Pp 769-791 (2023)
Both observations and ocean reanalyses show a pronounced seasonality in the strength of the Atlantic meridional overturning circulation (MOC) within the eastern North Atlantic subpolar gyre (eSPG). However, attributing this overturning seasonality to
Externí odkaz:
https://doaj.org/article/36ffa2d3213a457b8dc6b9693230ce14
Publikováno v:
Ocean Science, Vol 19, Pp 745-768 (2023)
The overturning streamfunction as measured at the OSNAP (Overturning in the Subpolar North Atlantic Program) mooring array represents the transformation of warm, salty Atlantic Water into cold, fresh North Atlantic Deep Water (NADW). The magnitude of
Externí odkaz:
https://doaj.org/article/b9a9cf58f31646929c6d36608368a021
Autor:
B. Speight, E. Colvin, E. D. Epurescu, J. Drummond, S. Verhoef, M. Pereira, D. G. Evans, M. Tischkowitz
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-7 (2022)
Abstract Germline pathogenic variants in BRCA1 and BRCA2 cause hereditary breast and ovarian cancer. The vast majority of these variants are inherited from a parent. De novo constitutional pathogenic variants are rare. Even fewer cases of constitutio
Externí odkaz:
https://doaj.org/article/77b5649900084f0fb8f3dc3ac8184fb3
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Constitutional mismatch repair deficiency syndrome results from bi-allelic inheritance of mutations affecting the key DNA mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. Individuals with bi-allelic mutations have a dysfunctional
Externí odkaz:
https://doaj.org/article/162f01c234a545989eb8ca03783d6fef
Autor:
Neal C. Ramchander, Neil A. J. Ryan, Thomas D. J. Walker, Lauren Harries, James Bolton, Tjalling Bosse, D. G. Evans, Emma J. Crosbie
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a significant minority is caused by Lynch syndrome (LS). This inherited cancer predisposition syndrome
Externí odkaz:
https://doaj.org/article/feb8adc93b1e445eb2b31f037913d8d9
Publikováno v:
International Journal of Surgical Oncology, Vol 2015 (2015)
Rates of contralateral risk-reducing mastectomy have increased substantially over the last decade. Surgical oncologists are often in the frontline, dealing with requests for this procedure. This paper reviews the current evidence base regarding contr
Externí odkaz:
https://doaj.org/article/5ef97d774c044042b680a6680c22f73d
Publikováno v:
International Journal of Surgical Oncology, Vol 2011 (2011)
Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1,
Externí odkaz:
https://doaj.org/article/4ee6f157f7cc44b68f38350e48863668
Autor:
O Michaeli, N Waespe, Laurence Brugières, Christian P. Kratz, Miriam J. Smith, Alexandra Russo, Steffen Hirsch, D G Evans, Saskia M. J. Hopman, B Doergeloh, H Salvador, V. Ridola, M. Jorgensen, T Milde, Léa Guerrini-Rousseau, B Claret, M Kuhlen
Publikováno v:
Familial Cancer
FAM CANCER
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Guerrini-Rousseau, L; Smith, M J; Kratz, C P; Doergeloh, B; Hirsch, S; Hopman, S M J; Jorgensen, M; Kuhlen, M; Michaeli, O; Milde, T; Ridola, V; Russo, A; Salvador, H; Waespe, N; Claret, B; Brugieres, L; Evans, D G (2021). Current recommendations for cancer surveillance in Gorlin syndrome: a report from the SIOPE host genome working group (SIOPE HGWG). Familial Cancer, 20(4), pp. 317-325. Springer 10.1007/s10689-021-00247-z
FAM CANCER
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Guerrini-Rousseau, L; Smith, M J; Kratz, C P; Doergeloh, B; Hirsch, S; Hopman, S M J; Jorgensen, M; Kuhlen, M; Michaeli, O; Milde, T; Ridola, V; Russo, A; Salvador, H; Waespe, N; Claret, B; Brugieres, L; Evans, D G (2021). Current recommendations for cancer surveillance in Gorlin syndrome: a report from the SIOPE host genome working group (SIOPE HGWG). Familial Cancer, 20(4), pp. 317-325. Springer 10.1007/s10689-021-00247-z
Gorlin syndrome (MIM 109,400), a cancer predisposition syndrome related to a constitutional pathogenic variation (PV) of a gene in the Sonic Hedgehog pathway (PTCH1 or SUFU), is associated with a broad spectrum of benign and malignant tumors. Basal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca2099ceaeeb84d4831a8b94a634268
http://europepmc.org/articles/PMC8484213
http://europepmc.org/articles/PMC8484213