Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D. G. Baden"'
Autor:
J M, Benson, F F, Hahn, B M, Tibbetts, L E, Bowen, T F, March, R J, Langley, T F, Murray, A J, Bourdelais, J, Naar, J, Zaias, D G, Baden
Publikováno v:
Harmful algae 2002 : proceedings of the Xth International Conference on Harmful Algae, St. Pete Beach, Florida, USA, October 21-25, 2002. International Conference on Harmful Algae (10th : 2002 : St. Pete Beach, Florida). 10
Brevetoxins are neurotoxins produced by the marine dinoflagellate Karenia brevis. Histopathologic examination of marine mammals dying following repeated exposure of brevetoxins during red tide events suggests that the respiratory tract, nervous, hema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c796a4779036cc2f6e8823a91121095
https://pubmed.ncbi.nlm.nih.gov/26436144
https://pubmed.ncbi.nlm.nih.gov/26436144
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 57:345-355
Brevetoxins are cyclic polyether neurotoxins produced by the marine dinoflagellate Ptychodiscus brevis. Blooms of P. brevis (red tides) are toxic to fish, marine mammals, and humans. Humans exposed to seaspray aerosols containing brevetoxins may expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c7b7578b2baf2fda23a11060668656
https://doi.org/10.1080/009841099157656
https://doi.org/10.1080/009841099157656
Publikováno v:
Applied Spectroscopy. 52:523-527
We have studied the UV-vis and vibrational spectra of the brevetoxins PbTx-2, PbTx-3, PbTx-9, and 2, 3, 27, 28, 41, 43-hexahydro-(reduced) PbTx-3. The absorption at 194 nm (ε ≈ 18 000 L mol−1 cm−1) of PbTx-2 and PbTx-3 is assigned to the Π–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0256a63deb59253cb5670ece1e08e3
https://doi.org/10.1366/0003702981944067
https://doi.org/10.1366/0003702981944067
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(2)
Brevetoxin-3 (PbTx-3), produced by marine dinoflagellates (Ptychodiscus brevis), is a lipophilic 11-ring polyether molecule that binds with high affinity to site 5 of the voltage-sensitive sodium (Na+) channel. The effects of PbTx-3 and its derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4d4c824a6a8e2e7eea9bf0e40f4c331
https://pubmed.ncbi.nlm.nih.gov/9454792
https://pubmed.ncbi.nlm.nih.gov/9454792
Publikováno v:
Natural toxins. 5(5)
Brevetoxins are produced by the marine dinoflagellate Ptychodiscus brevis, an organism linked to red tide outbreaks, and the accompanying toxicity to marine animals and to neurotoxic shellfish poisoning in humans. Brevetoxins bind with high affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d66976da44ee4ed28c29cfcec9c262b
https://pubmed.ncbi.nlm.nih.gov/9496378
https://pubmed.ncbi.nlm.nih.gov/9496378
Autor:
P L, Whitney, D G, Baden
Publikováno v:
Natural toxins. 4(6)
Brevetoxins bind with high affinity to the voltage-sensitive sodium channel and cause nerve cell depolarization and increased sodium ion conductance. Using 0.6 nM tritium-labeled brevetoxin-3 and freshly prepared synaptosomes from fresh or frozen rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31c7ab8759a97cbb582bf2e2612d99c6
https://pubmed.ncbi.nlm.nih.gov/9029551
https://pubmed.ncbi.nlm.nih.gov/9029551
Autor:
D G, Baden, R, Melinek, V, Sechet, V L, Trainer, D R, Schultz, K S, Rein, C R, Tomas, J, Delgado, L, Hale
Publikováno v:
Journal of AOAC International. 78(2)
Polyether marine toxins are responsible for the seafood intoxication phenomena known as neurotoxic shellfish poisoning (due to brevetoxins), ciguatera (due to ciguatoxin), and diarrheic shellfish poisoning (due to okadaic acid). Using traditional tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::235587e2a97be4fd4b4661c0431059de
https://pubmed.ncbi.nlm.nih.gov/7538840
https://pubmed.ncbi.nlm.nih.gov/7538840
Publikováno v:
Journal of AOAC International. 78(2)
Antiserum against PbTx-2-type brevetoxins was produced by immunizing rabbits with a PbTx-2-bovine serum albumin (BSA) conjugate. This serum had a higher affinity, but lower titer, than our current goat serum. Using 4 natural brevetoxins and 6 synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28b3fc5a76c0fdebf4e1f0a6b3d3e2f0
https://pubmed.ncbi.nlm.nih.gov/7538841
https://pubmed.ncbi.nlm.nih.gov/7538841
Publikováno v:
Journal of AOAC International. 78(2)
Specific binding of the marine toxins saxitoxin, tetrodotoxin, and brevetoxin to the rat brain sodium channel is demonstrated using purified sodium channels reconstituted into phospholipid vesicles. Restoration of sodium channel function and binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f369b140e938c18385e829f1799fc1e
https://pubmed.ncbi.nlm.nih.gov/7756870
https://pubmed.ncbi.nlm.nih.gov/7756870
Publikováno v:
The Journal of biological chemistry. 269(31)
To identify the binding domain for brevetoxins, a family of lipid-soluble neurotoxins acting at Na+ channel receptor site 5, purified and reconstituted rat brain Na+ channels were photolabeled with p-azidobenzoyl tritium-labeled brevetoxin, and the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fa8708cd60171abfa690057928249d1
https://pubmed.ncbi.nlm.nih.gov/8051073
https://pubmed.ncbi.nlm.nih.gov/8051073