Zobrazeno 1 - 10
of 68
pro vyhledávání: '"D. F. Young"'
Autor:
D F, Young, J, Andrejeva, X, Li, F, Inesta-Vaquera, C, Dong, V H, Cowling, S, Goodbourn, R E, Randall
Publikováno v:
Journal of Virology
We have previously shown that IFIT1 is primarily responsible for the antiviral action of interferon (IFN) alpha/beta against parainfluenza virus type 5 (PIV5), selectively inhibiting the translation of PIV5 mRNAs. Here we report that while PIV2, PIV5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ec42386648b5e913f484f277c33a83
https://ueaeprints.uea.ac.uk/id/eprint/60605/
https://ueaeprints.uea.ac.uk/id/eprint/60605/
A small 14 amino acid oligopeptide tag (termed SV5-Pk) was fused onto the carboxy-terminus of simian immunodeficiency virus gp160 expressed from a recombinant baculovirus. The presence of the Pk tag had no obvious effect on the expression and glycosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf52435eea006ce6166c1a55bf3fc7f
https://doi.org/10.1016/0166-0934(95)00003-d
https://doi.org/10.1016/0166-0934(95)00003-d
Publikováno v:
Virology
It is generally thought that pathogen-associated molecular patterns (PAMPs) responsible for triggering interferon (IFN) induction are produced during virus replication and, to limit the activation of the IFN response by these PAMPs, viruses encode an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6c3fd0cc62de396aca133ca24f88bd
Autor:
Marian J. Killip, M. Schneider, S. Chen, Steve Goodbourn, Jessie Short, D. F. Young, Richard E. Randall
Publikováno v:
Virology
The infection of cells by RNA viruses is associated with the recognition of virus PAMPs (pathogen-associated molecular patterns) and the production of type I interferon (IFN). To counter this, most, if not all, RNA viruses encode antagonists of the I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2d57f6ca87e8493bb81be56647fb8c
https://doi.org/10.1016/j.virol.2010.08.008
https://doi.org/10.1016/j.virol.2010.08.008
Autor:
Bertus K. Rima, Ken Lemon, W. P. Duprex, Yun-Hsiang Chen, D. F. Young, M. C. Galiano, Richard E. Randall, J. Andrejeva
Publikováno v:
The Journal of General Virology
Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naive ('IFN-competent' Hep2) cells but grew to high titres in 'IFN-comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995380b1bd3eeca6886d27ffdcc602fa
http://europepmc.org/articles/PMC2885035
http://europepmc.org/articles/PMC2885035
Publikováno v:
Virology. 363:166-173
We have previously reported that the addition of interferon (IFN) to the culture medium of Vero cells (which cannot produce IFN) that were infected with the CPI− strain of parainfluenza virus 5 (PIV5, formally known as SV5), that fails to block IFN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6c39d5414630970abcb0d9229bd94c
https://doi.org/10.1016/j.virol.2007.01.014
https://doi.org/10.1016/j.virol.2007.01.014
Publikováno v:
Journal of General Virology. 86:151-158
Previous work has documented that the V protein of simian virus 5 (SV5) targets STAT1 for proteasome-mediated degradation, whilst the V protein of human parainfluenza virus type 2 (hPIV2) targets STAT2. Here, it was shown that the processes of ubiqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaabbe6f4cd3f3c1be7b56a96de28ba3
https://doi.org/10.1099/vir.0.80263-0
https://doi.org/10.1099/vir.0.80263-0
Autor:
Nicola Stock, D. F. Young, Nikolaos Chatziandreou, Kathrin Hagmaier, Richard E. Randall, Duncan J. McGeoch, J. Andrejeva
Publikováno v:
Journal of General Virology. 85:3007-3016
Sequence comparison of the V/P and F genes of 13 human, canine, porcine and simian isolates of simian virus 5 (SV5) revealed a surprising lack of sequence variation at both the nucleotide and amino acid levels (0–3 %), even though the viruses were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdf3474ef93730cf71a3469be086e1c
https://doi.org/10.1099/vir.0.80200-0
https://doi.org/10.1099/vir.0.80200-0
Autor:
Richard M. Elliott, Peter L. Collins, Robert A. Lamb, A. Livingstone, Richard E. Randall, D. F. Young, Stephen Goodbourn, L. Andrejeva
Publikováno v:
Journal of Virology. 77:2174-2181
The V protein of the paramyxovirus simian virus 5 blocks interferon (IFN) signaling by targeting STAT1 for proteasome-mediated degradation. Here we report on the isolation of human cell lines that express the V protein and can no longer respond to IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240dd28d6652e6871a6a84c04418131d
https://doi.org/10.1128/jvi.77.3.2174-2181.2003
https://doi.org/10.1128/jvi.77.3.2174-2181.2003
Publikováno v:
Virology. 293:234-242
CPI(+) and CPI(-) are two canine isolates of simian virus 5 (SV5). CPI(+) was originally isolated from the cerebrospinal fluid of a dog with temporary posterior paralysis and CPI(-) was recovered at 12 days p.i. from the brain tissue of a dog experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840f72f013c74463e82d8b93dfff5ce3
https://doi.org/10.1006/viro.2001.1302
https://doi.org/10.1006/viro.2001.1302