Zobrazeno 1 - 10
of 16
pro vyhledávání: '"D. F. Rigel"'
Publikováno v:
British journal of pharmacology. 171(22)
Previously, a systems pharmacology model was developed characterizing drug effects on the interrelationship between mean arterial pressure (MAP), cardiac output (CO) and total peripheral resistance (TPR). The present investigation aims to (i) extend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eda0231f9f78d01e9ea2f6fb18608fc2
https://pubmed.ncbi.nlm.nih.gov/24962208
https://pubmed.ncbi.nlm.nih.gov/24962208
Autor:
S. S. Shetty, D. F. Rigel
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 272:H2054-H2064
We evaluated the effects of endothelin-1 (ET-1) and prostaglandin F2alpha (PGF2alpha) selectively on conduit coronary artery diameter using a novel approach in which the local concentration of vasoactive agent was controlled and maintained in vivo. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bb3034527564b6abe0ea4f47a3585b
https://doi.org/10.1152/ajpheart.1997.272.4.h2054
https://doi.org/10.1152/ajpheart.1997.272.4.h2054
Publikováno v:
Circulation Research. 72:1091-1102
Recombinant desulfatohirudin (HI), a potent and specific thrombin inhibitor, was compared with heparin (HE) as an adjunct to streptokinase thrombolysis. In pentobarbital-anesthetized dogs, an occlusive thrombus (whole blood+thrombin) was introduced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46211e5fb75ec9a0e00076104a875f52
https://doi.org/10.1161/01.res.72.5.1091
https://doi.org/10.1161/01.res.72.5.1091
Autor:
David A. Lathrop, D F Rigel
Publikováno v:
Circulation Research. 67:1323-1333
Our study was designed to determine the cardiac electrophysiological influence of vasoactive intestinal polypeptide (VIP) in conscious dogs. Dogs (n = 8) were chronically instrumented with arterial and venous catheters, cervical vagal cooling coils,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5674693d0e651459170d36420afd88
https://doi.org/10.1161/01.res.67.6.1323
https://doi.org/10.1161/01.res.67.6.1323
Publikováno v:
Annals of Surgery. 211:323-328
The present study was designed to determine whether reduced amino acid uptake in skeletal muscle during endotoxemia is due to associated hypotension or is caused by a factor present in plasma. Three series of experiments were performed. In the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080601e9bfb08eba66cedb914e3aaec4
https://doi.org/10.1097/00000658-199003000-00003
https://doi.org/10.1097/00000658-199003000-00003
Publikováno v:
Peptide research. 5(2)
Sculpin pancreatic polypeptide (PP) and anglerfish peptide Y (aPY-amide) are 36-residue peptide amides isolated from the pancreas of the respective species of fish. They are 86% homologous, and exhibit about 65% homology to porcine neuropeptide Y (NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0ddc8876c420f925c4e5565ea1c8d03
https://pubmed.ncbi.nlm.nih.gov/1581637
https://pubmed.ncbi.nlm.nih.gov/1581637
Autor:
D. F. Rigel, D. A. Lathrop
Publikováno v:
The American journal of physiology. 261(2 Pt 2)
Effects of the cardiac neuropeptide vasoactive intestinal polypeptide (VIP) and isoproterenol (ISO) were compared on sinus nodal, subsidiary atrial, and atrioventricular junctional pacemaker automaticity in pentobarbital sodium-anesthetized dogs (n =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8cdc975e9cbff7c2ea678e7574b4ad
https://pubmed.ncbi.nlm.nih.gov/1877672
https://pubmed.ncbi.nlm.nih.gov/1877672
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 257:H1082-H1087
Contractile effects of the cardiac neuropeptides vasoactive intestinal polypeptide (VIP), peptide histidine isoleucine (PHI), neuropeptide Y (NPY), calcitonin gene-related peptide (CGRP), and neurotensin (NT) were compared with those of l-isoproteren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d216ffcdddc22e0f0c3aa567403a03
https://doi.org/10.1152/ajpheart.1989.257.4.h1082
https://doi.org/10.1152/ajpheart.1989.257.4.h1082
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 246:H168-H173
In conscious dogs the heart rate after atropine is higher than after bilateral vagotomy; we have termed the additional heart rate with atropine "excess tachycardia" (ET). In six dogs the cervical vagosympathetic trunks were exteriorized in skin tubes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bd21ad7995fe56224fa967dfa445d1
https://doi.org/10.1152/ajpheart.1984.246.2.h168
https://doi.org/10.1152/ajpheart.1984.246.2.h168
Publikováno v:
Peptide research. 1(1)
Peptide YY (PYY) is a 36 residue peptide amide isolated from porcine intestine. It has distinct structural homology with neuropeptide Y (NPY) and pancreatic polypeptide (PP). Endocrine cells of pancreas and gut of mammals have been shown to contain P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7e05655dd57952ea873782f72b54062
https://pubmed.ncbi.nlm.nih.gov/2856553
https://pubmed.ncbi.nlm.nih.gov/2856553