Zobrazeno 1 - 10
of 81
pro vyhledávání: '"D. F. Mosher"'
Publikováno v:
Cellular and molecular life sciences : CMLS. 65(5)
Thrombospondins are large secreted, multi-modular, calcium-binding glycoproteins that have complex roles in mediating cellular processes. Determination of high-resolution structures of thrombospondins has revealed unique and interesting protein motif
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(11)
Asthma is characterized by an airway inflammatory infiltrate that is rich in eosinophilic leukocytes. Cellular fibronectin and VCAM-1, ligands for alpha4 integrins, are enriched in the fluid of airways of allergic patients subjected to Ag challenge.
Publikováno v:
Blood. 93(9)
Fibronectin matrix assembly is a cell-dependent process mediated by cell surface binding sites for the 70-kD N-terminal portion of fibronectin. We have shown that Rho-dependent cytoskeleton reorganization induced by lysophosphatidic acid (LPA) or the
Publikováno v:
The Journal of biological chemistry. 273(6)
We developed a method using a single set of degenerate oligonucleotide primers for amplification of the conserved active site of transglutaminases by reverse transcription-polymerase chain reaction (RT-PCR) and identification of the PCR products by c
Autor:
Q, Zhang, D F, Mosher
Publikováno v:
The Journal of biological chemistry. 271(52)
Cell surface molecules on adherent cells that bind 125I-labeled fibronectin or its 70-kDa N-terminal fragment were identified by cross-linking with factor XIIIa and by photoaffinity labeling. Such cross-linking caused the 70-kDa fragment to become as
Publikováno v:
The Journal of biological chemistry. 271(27)
Thrombospondin 1 (TSP1) and thrombospondin 2 (TSP2) are members of the thrombospondin family that have a similar structural organization but somewhat different functional activities. Iodinated recombinant mouse TSP2 bound to NIH 3T3 cells and was int
Autor:
H, Chen, D F, Mosher
Publikováno v:
The Journal of biological chemistry. 271(15)
Fibronectin exists in a soluble form in body fluids and as a fibrillar component of the extracellular matrix. Matrix fibronectin associates as large complexes in SDS unless a reducing reagent is also present. This observation suggests that complex fo
Publikováno v:
American journal of hematology. 51(4)
Thrombospondin (TSP), a large protein found in platelet alpha-granules (as TSP-1), mediates adhesion of sickle reticulocytes to cultured vascular endothelium. To further explore the physiologic relevance of this observation, we have measured plasma T
Autor:
D F, Mosher
Publikováno v:
Thrombosis and haemostasis. 74(1)
Assembly of fibronectin into the provisional fibrillar matrix of embryonic tissues and wounds is a complicated process by which the intracellular cytoskeleton determines the pattern of assembly of extracellular matrix and vice versa. Assembly is rest
Publikováno v:
The Journal of biological chemistry. 269(51)
A baculovirus system was used to express full-length recombinant mouse thrombospondin 2 (rTSP2) as a disulfide-bonded homotrimer with an NH2 terminus beginning with Asp20.rTSP2, like TSP1, was more sensitive to trypsin digestion if depleted of calciu