Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D. F. Mierke"'
Autor:
D F Mierke, Carla Isernia, Michele Saviano, P. Di Lello, E Benedetti, Stefania Galdiero, C Pedone, C Bassarello
Publikováno v:
The Journal of Peptide Research. 65:200-208
The Antennapedia homeodomain structure consists of four helices. The helices II and III are connected by a tripeptide that forms a turn, and constitute the well-known helix-turn-helix motif. The recognition helix penetrates the DNA major groove, give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1563180342d7fbc823dc47029d5267bf
https://doi.org/10.1111/j.1399-3011.2005.00226.x
https://doi.org/10.1111/j.1399-3011.2005.00226.x
Autor:
C, Giragossian, D F, Mierke
Publikováno v:
Biochemistry. 40:3804-3809
The interaction of the C-terminal octapeptide of cholecystokinin, CCK-8, with the third extracellular loop of human cholecystokinin-A receptor, CCK(A)-R(329-357), has been probed by high-resolution NMR and extensive computer simulations. The structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86dfba23b5fbcdb239510f53490e2d4
https://doi.org/10.1021/bi002659n
https://doi.org/10.1021/bi002659n
Autor:
J. Saulitis, Stephan Seip, Martin Will, S. Steuernagel, D. F. Mierke, Horst Kessler, Thomas Wein
Publikováno v:
Biopolymers. 32:427-433
The constitution and configuration of Ro 09-0198 (cinnamycin) have been determined in DMSO. Further investigations in aqueous solution, in SDS micelles and in a lipid bilayer have been done to study the influence of different environments on the conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f627317c143c6f3203942344dc52012
https://doi.org/10.1002/bip.360320420
https://doi.org/10.1002/bip.360320420
Autor:
BENEDETTI, ETTORE, C. ISERNIA, NASTRI, FLAVIA, C. PEDONE, M. SAVIANO, D. F. MIERKE, P. MELCHIORRI, L. NEGRI, R. L. POTENZA, C. SEVERINI, V. ERSPAMER
To identify the peptide conformation that is preferentially recognized by the receptor, we have synthetized by solidphase method a series of deltorphin I analogs with increasing selectivity for δ- and μ-opioid receptor. Structure-selectivity relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::82a3030dbaadb089624cbed60d1fe0dc
http://hdl.handle.net/11591/184387
http://hdl.handle.net/11591/184387
Autor:
G, Saviano, F, Rossi, E, Benedetti, C, Pedone, D F, Mierke, A, Maione, G, Zanotti, T, Tancredi, M, Saviano
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 7(6)
The conformational features of both free and Ca2+-complexed cyclo[Pro-Phe-Phe-Ala-Xaa]2 (with Xaa= Glu(OtBu), Lys(CIZ), Leu, and Ala) in solution have been determined by NMR spectroscopy and extensive distance-geometry calculations. The decapeptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ae26a1f6d431ce67f0f1ffa7300dea9
https://pubmed.ncbi.nlm.nih.gov/11322543
https://pubmed.ncbi.nlm.nih.gov/11322543
Publikováno v:
The Journal of biological chemistry. 276(25)
Molecular models for the interaction of substance P (SP) with its G protein-coupled receptor, the neurokinin-1 receptor (NK-1R), have been developed. The ligand.receptor complex is based on experimental data from a series of photoaffinity labeling ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a7b83edff78216fc6215466dec23c1b
https://pubmed.ncbi.nlm.nih.gov/11294871
https://pubmed.ncbi.nlm.nih.gov/11294871
Publikováno v:
Biopolymers. 42(7)
The structure and dynamics of the ionophoric antibiotic monensin in the presence of micelles have been determined. The conformation of monensin was derived from 50 nuclear Overhauser enhancement (NOE) derived distance restraints and metric-matrix bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfb5ea954d187b1fb9acf1e4231de4df
https://pubmed.ncbi.nlm.nih.gov/10904548
https://pubmed.ncbi.nlm.nih.gov/10904548
Autor:
M, Pellegrini, D F, Mierke
Publikováno v:
Biopolymers. 51(3)
The structural characterization of peptide hormones and their interaction with G-protein (guanine nucleotide-binding regulatory protein) coupled receptors by high-resolution nmr is described. The general approaches utilized can be categorized into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a193442356341c4eb1eddc338da1bdd
https://pubmed.ncbi.nlm.nih.gov/10516572
https://pubmed.ncbi.nlm.nih.gov/10516572
Autor:
S G, Grdadolnik, D F, Mierke
Publikováno v:
Biopolymers. 42(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff3b7eb13e6d9f33a5549dadbeaccdf5
https://pubmed.ncbi.nlm.nih.gov/9358729
https://pubmed.ncbi.nlm.nih.gov/9358729
Publikováno v:
Biopolymers. 40(6)
The third-cytoplasmic loop of the G-protein coupled receptor responsible for the activity of parathyroid hormone and parathyroid hormone-related protein has been structurally characterized in aqueous solution in the presence of sodium dodecylsulfate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a78c13e6433ff48c619afb9a936c6322
https://pubmed.ncbi.nlm.nih.gov/9140202
https://pubmed.ncbi.nlm.nih.gov/9140202