Výsledky vyhledávání - "D. F. Melton"

Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines

Autor: D. F. Melton, Edwin L. Thomas, M. Margaret Jefferson, Matthew B. Grisham

Publikováno v: Journal of Biological Chemistry. 259:10404-10413

Isolated human neutrophilic leukocytes were stimulated to produce hydrogen peroxide (H2O2) and to secrete cytoplasmic granule components including myeloperoxidase into the medium. Myeloperoxidase catalyzed the oxidation of chloride (Cl-) by H2O2 to y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b1e47d2f83fb5443aeb3445e34cfa65
https://doi.org/10.1016/s0021-9258(18)90979-8

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Evidence for a role of taurine in the in vitro oxidative toxicity of neutrophils toward erythrocytes

Autor: Matthew B. Grisham, Edwin L. Thomas, M. M. Jefferson, D. F. Melton

Publikováno v: Journal of Biological Chemistry. 260:3321-3329

Production of hydrogen peroxide and secretion of myeloperoxidase by stimulated neutrophils resulted in myeloperoxidase-catalyzed oxidation of chloride to hypochlorous acid (HOCl), the reaction of HOCl with taurine to yield taurine monochloramine (Tau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e151091c5a463a2f4c2b87b6e8adc675
https://doi.org/10.1016/s0021-9258(19)83623-2

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