Zobrazeno 1 - 10
of 307
pro vyhledávání: '"D. Emanuel"'
Autor:
Yi Luo, Lijian Shao, Jianhui Chang, Wei Feng, Y. Lucy Liu, Michele H. Cottler-Fox, Peter D. Emanuel, Martin Hauer-Jensen, Irwin D. Bernstein, Lingbo Liu, Xing Chen, Jianfeng Zhou, Peter J. Murray, Daohong Zhou
Publikováno v:
Blood Advances, Vol 2, Iss 8, Pp 859-870 (2018)
Abstract: Uncovering the cellular and molecular mechanisms by which hematopoietic stem cell (HSC) self-renewal is regulated can lead to the development of new strategies for promoting ex vivo HSC expansion. Here, we report the discovery that alternat
Externí odkaz:
https://doaj.org/article/818b79add26b4135990fa6d6d894d3d2
Publikováno v:
Caldasia, 2014 Dec . 36(2), 217-230.
Externí odkaz:
https://www.jstor.org/stable/90008377
Publikováno v:
Annals of Emergency Medicine. 80:S85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac70102e0d1a90e77b6231ececbda2fc
https://doi.org/10.1016/j.annemergmed.2022.08.210
https://doi.org/10.1016/j.annemergmed.2022.08.210
Autor:
Natalia Colorado, Peter D. Emanuel, Delli Robinson, Yuqing Liu, Erich A. Peterson, Donald J. Johann, Daohong Zhou, Alice Bertaina, Nitza Vara, Nicholas J. Baltz, Shelly Lensing, Jingliao Zhang, Yan Yan, Y. Lucy Liu, Xin Zhang
Publikováno v:
Blood Adv
It is not clear whether disrupted age-specific hematopoiesis contributes to the complex manifestations in leukemia patients who carry identical mutations, particularly in pediatric and adult patients with similar clinical characteristics. By studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b12c4c51b6b0995f7f7fd539ad17a1
https://europepmc.org/articles/PMC7422126/
https://europepmc.org/articles/PMC7422126/
Publikováno v:
Blood. 138:1464-1464
MLN0128 (TAK-228, INK128) is an investigational new drug (IND) that is currently being evaluated in clinical trials and has showed promising efficacies in patients with solid cancer. MLN0128 is one of the second generation of inhibitors for mammalian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e08afdcc71ac9ec4680412ce905cff
https://doi.org/10.1182/blood-2021-151976
https://doi.org/10.1182/blood-2021-151976
Autor:
Angela Pennisi, Xueyan Guo, Behjatolah Monzavi-Karbassi, Laura F. Hutchins, Eric R. Siegel, Peter D. Emanuel, Thomas Kieber-Emmons, Issam Makhoul, Fariba Jousheghany, Anastas Pashov
Publikováno v:
Oncotarget
Tumor-associated carbohydrate antigens (TACAs) support cell survival that could be interrupted by anti-TACA antibodies. Among TACAs that mediate cell survival signals are the neolactoseries antigen Lewis Y (LeY) and the ganglioside GD2. To induce sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2612365320f7cd052af1668b482ae448
https://doi.org/10.18632/oncotarget.21959
https://doi.org/10.18632/oncotarget.21959
Autor:
Laura F. Hutchins, Angela Pennisi, Peter D. Emanuel, Behjatolah Monzavi Karbassi, Thomas Kieber-Emmons, Issam Makhoul, Fariba Jousheghany, Eric R. Siegel
Publikováno v:
Cancer Research. 77:P6-10
Active immunization of cancer patients to induce de novo functional anti-tumor immune responses is an alternative/complementary approach to chemotherapy. Tumor vaccines hold the potential to deliver durable, specific and systemic anti-tumor responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63269d3aa3207391e69727ab29c583fa
https://doi.org/10.1158/1538-7445.sabcs16-p6-10-06
https://doi.org/10.1158/1538-7445.sabcs16-p6-10-06
Autor:
Jingliao Zhang, Yan Yan, Nicholas J. Baltz, Peter D. Emanuel, Y. Lucy Liu, Priyangi A. Malaviarachchi, Zhifu Xiang
Publikováno v:
Cellular signalling. 50
Constitutively activated MAPK and AKT signaling pathways are often found in solid tumors and leukemias. PTEN is one of the tumor suppressors that are frequently found deficient in patients with late-stage cancers or leukemias. In this study we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faab8c17074b42fe9fb3efc4809e9848
https://pubmed.ncbi.nlm.nih.gov/29964149
https://pubmed.ncbi.nlm.nih.gov/29964149
Autor:
Sara Seepo, Kyle Beckman, Clifford M. Takemoto, Todd Cooper, Johann Hitzler, Philip A. Roehrs, Todd R. Golub, Tiffany Y. Chang, Scott R. Olsen, Tali Mazor, Patrick A. Brown, Robert J. Hayashi, Mara Rosenberg, Reuven J. Schore, Rakesh K. Goyal, Philip M. Monteleone, Emilio Esquivel, Jeffrey A. Toretsky, Elliot Stieglitz, Robert B. Gerbing, Mignon L. Loh, Adam B. Olshen, Gad Getz, Yong Dong Wang, Yongjin Li, Benjamin Carcamo, Laura C. Gelston, Kimo C. Stine, Ghada Abusin, Chip Stewart, Peter D. Emanuel, Todd A. Alonzo, Y. Lucy Liu, Yoav Messinger, Gary V. Dahl, Joseph F. Costello, Kimberly Stegmaier, Christopher Hugge, Donald H. Mahoney, Jing Ma, Eneida R. Nemecek, Sophie Archambeault, Amaro Taylor-Weiner, Ariel Yu, Mark Fluchel, Tanja A. Gruber, Michael Briones
Publikováno v:
Nature genetics
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in NF1, NRAS, KRAS, PTPN11 and CBL occur in 85% of patients, yet there are currently no risk stratification algorithms capabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8865d5d13f14756a5f9ec0e886b02ab9
https://doi.org/10.1038/ng.3400
https://doi.org/10.1038/ng.3400
Autor:
Al-Ola Abdallah, Peter Papenhausen, Peter D. Emanuel, Rangaswamy Govindarajan, Steven A. Schichman, Zhifu Xiang, Paulette Mehta
Publikováno v:
Cancer Genetics. 208:96-100
The role of MYC and EZH2 in acute myeloid leukemia (AML) pathogenesis is poorly understood. Herein we present a case of AML with MYC amplification in marker chromosomes and a microdeletion of chromosome 7 below cytogenetic resolution. The karyotype o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86096bee4925cc002e0afd05bf5bbb35
https://doi.org/10.1016/j.cancergen.2015.01.010
https://doi.org/10.1016/j.cancergen.2015.01.010