Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D. E. Horning"'
Autor:
D. E. Horning, J. M. Muchowski
Publikováno v:
Canadian Journal of Chemistry. 51:2349-2352
Stable salts of 3-mercapto-1,2,5-thiadiazoles were prepared by the alkaline hydrolysis of the corresponding N,N-dimethylthionocarbamates.
Autor:
J. M. Muchowski, D. E. Horning
Publikováno v:
Canadian Journal of Chemistry. 50:3079-3082
1,3,4-Oxadiazole-2-thione was prepared by decarboxylation of the corresponding 5-carboxylic acid. Spectral data supported the predominant, if not exclusive, existence of the thione form in solution.
Publikováno v:
Canadian Journal of Chemistry. 48:975-982
It is shown that the sodium hydride (in dimethyl formamide) induced elimination of hydrogen bromide from 1,3-dibromo-2-(tetrahydropyran-2-yloxy)propane (3) can be considered to result in the in situ formation of 3-bromo-2-(tetrahydropyran-2-yloxy)pro
Autor:
J. M. Muchowski, D. E. Horning
Publikováno v:
Canadian Journal of Chemistry. 49:485-492
The synthesis and spectral properties of some two- and three-carbon ortho-bridged analogues of the analgesic methadone are described. These compounds were devoid of analgesic activity.
Publikováno v:
Canadian Journal of Chemistry. 49:246-254
The base-induced alkylation of 4-unsubstituted homophthalimides with 1-bromo-2-chloroethane produced the spirocyclopropane compounds 4. The structures of these compounds were supported by their spectral properties and by their susceptibility towards
Publikováno v:
Canadian Journal of Chemistry. 49:2785-2796
The electrophilic substitution of N-alkylated isocarbostyrils was examined in considerable detail. Bromination, acylation, nitration, and acid-catalyzed condensation with formaldehyde occurred exclusively at C-4 under relatively mild conditions. The
Publikováno v:
Canadian Journal of Chemistry. 47:4327-4333
The synthesis of several 11-substituted-5,6-dihydro-11H-dibenzo[b,e]azepin-6-ones, and an improved method of preparing 5-cyano-10,11-dihydro-5H-dibenzo[a,d]cycloheptene and 12-cyano-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene are described.A descripti
Publikováno v:
Canadian Journal of Chemistry. 50:3886-3891
It was shown that 3-phenyl-3-(2-aminoethyl)phthalide (6, R = H) and its N-methyl analog (6, R = CH3) existed in the amino lactone form in solution at room temperature. In the absence of solvents, however, these compounds underwent a spontaneous trans
Publikováno v:
Canadian Journal of Chemistry. 49:2797-2802
The sulfuric acid catalyzed acylation of 2-methyl-5-nitroisocarbostyril with carboxylic acid anhydrides gave the corresponding 4-acylated derivatives 3, which underwent reductive cyclization to 2-substituted derivatives of 4-methyl-1,3,4,5-tetrahydro
Autor:
J. M. Muchowski, D. E. Horning
Publikováno v:
Canadian Journal of Chemistry. 48:193-195
The synthesis of selected indole-3-aldehydes from the corresponding indoles and the DMF – acyl halide complex is described.