Zobrazeno 1 - 10 of 21 pro vyhledávání: '"D. E. Grigoriadis"'
1
Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors
Autor: Argyrios G. Arvanitis, D. E. Grigoriadis, Everett Latham Scholfield, Peter G. Heytler, Robert J. Chorvat, Jack Bowdle
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 6:115-120
A series of alkylbenzylethers of substituted hydroquinone analogs of 4-(3-chlorophenyl methyloxy)-phenoxybutyronitrile I, and alcohol II were synthesized as monoamine oxidase (MAO) inhibitors. Incorporation of electron-withdrawing groups on the hydro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b73584ee932fdad5e781bb30c2f1df3
https://doi.org/10.1016/0960-894x(95)00561-7
Zobrazit plný text záznamu
2
Relative affinities of dopaminergic drugs at dopamine D2 and D3 receptors
Autor: Beth Levant, Errol B. De Souza, D. E. Grigoriadis
Publikováno v: European Journal of Pharmacology. 278:243-247
Quantitative autoradiography was used to evaluate the pharmacological profile of dopamine D2-like receptors labeled by [125I]iodosulpiride. Caudate/putamen, a brain region associated primarily with dopamine D2 receptor mRNA, was used as a prototypica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2fb4c5c73308170ef78c003c953da7
https://doi.org/10.1016/0014-2999(95)00160-m
Zobrazit plný text záznamu
3
Novel conformationally restricted aromatic piperidines as selective sigma receptor ligands
Autor: D. E. Grigoriadis, Paul J. Gilligan, Alexander L. Johnson, Gary A. Cain, S. William Tam, Charles J. Eyermann, Thomas E. Christos
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 4:329-334
A series of novel conjugated aromatic 4-amino- and 4-amido-piperidines which are potent sigma receptor ligands are described. These ligands exhibited good to excellent selectivities for binding at sigma versus D2 and 5-HT2 receptors.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f671b10ed60a67a358c3a3049c6b33a
https://doi.org/10.1016/s0960-894x(01)80138-4
Zobrazit plný text záznamu
4
Monoamine oxidase inhibitors inhibit [3H]quinpirole binding in rat striatal membranes
Autor: Errol B. DeSouza, D. E. Grigoriadis, Beth Levant
Publikováno v: European Journal of Pharmacology: Molecular Pharmacology. 246:171-178
This study describes interactions of monoamine oxidase inhibitors at binding sites labeled by [3H]quinpirole, a putatively selective ligand for dopamine D2-like receptors, in in vitro binding assays in rat brain. Monoamine oxidase inhibitors potently
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785a85567781cea11d687e5e16bbd01b
https://doi.org/10.1016/0922-4106(93)90095-q
Zobrazit plný text záznamu
8
Preterm birth: associated neuroendocrine, medical, and behavioral risk factors
Autor: K, Erickson, P, Thorsen, G, Chrousos, D E, Grigoriadis, O, Khongsaly, J, McGregor, J, Schulkin
Publikováno v: The Journal of clinical endocrinology and metabolism. 86(6)
Increased CRH secretion by the placenta of pregnant women has been associated with preterm birth. Certain indices of risk, both medical and psychosocial in nature, have been linked to preterm delivery. Levels of total, bound, and free CRH, CRH-bindin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60a98f58772aa210fe681efa6a1a0d2d
https://pubmed.ncbi.nlm.nih.gov/11397853
Zobrazit plný text záznamu
9
Role of corticotropin-releasing factor (CRF) receptors in the anorexic syndrome induced by CRF
Autor: M A, Pelleymounter, M, Joppa, M, Carmouche, M J, Cullen, B, Brown, B, Murphy, D E, Grigoriadis, N, Ling, A C, Foster
Publikováno v: The Journal of pharmacology and experimental therapeutics. 293(3)
Genetic manipulations of corticotropin-releasing factor (CRF)(1) and CRF(2) receptors have resulted in data suggesting that the CRF(2) receptor could mediate the effects of CRF on appetite or satiety. We have attempted to obtain pharmacological evide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::18f3fcd16c272a8b289d822816f780cd
https://pubmed.ncbi.nlm.nih.gov/10869378
Zobrazit plný text záznamu
10
Recent advances with the CRF1 receptor: design of small molecule inhibitors, receptor subtypes and clinical indications
Autor: J R, McCarthy, S C, Heinrichs, D E, Grigoriadis
Publikováno v: Current pharmaceutical design. 5(5)
Corticotropin-releasing factor (CRF) has been widely implicated as playing a major role in modulating the endocrine, autonomic, behavioral and immune responses to stress. The recent cloning of multiple receptors for CRF as well as the discovery of no
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ffab2365edb2e23079fce259ddf415a4
https://pubmed.ncbi.nlm.nih.gov/10213797
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje