Zobrazeno 1 - 10 of 10 pro vyhledávání: '"D. E. Graves"'
3
Altered motor control and spasticity after spinal cord injury: subjective and objective assessment
Autor: A M, Sherwood, D E, Graves, M M, Priebe
Publikováno v: Journal of rehabilitation research and development. 37(1)
This study of measures of spasticity, or altered motor control, compares the clinically used Ashworth scale with a method based on surface electromyographic (sEMG) recordings called brain motor control assessment (BMCA) in a group of 97 subjects with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff5bdef860c44ad7eb9651dde48c81a2
https://pubmed.ncbi.nlm.nih.gov/10847571
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4
5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity
Autor: J A, Spicer, G J, Finlay, B C, Baguley, L, Velea, D E, Graves, W A, Denny
Publikováno v: Anti-cancer drug design. 14(1)
DACA is a DNA-intercalating agent and dual topoisomerase (topo) I/II inhibitor currently in clinical trial as an anticancer drug. Substitutions in the acridine ring of DACA have significant effects on biological activity, with 5-substituted analogues
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54b7c42114b81a3f0cd8f2e1d46a156e
https://pubmed.ncbi.nlm.nih.gov/10363026
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5
Structure-activity studies of amsacrine analogs in drug resistant human leukemia cell lines expressing either altered DNA topoisomerase II or P-glycoprotein
Autor: B, Granzen, D E, Graves, B C, Baguley, M K, Danks, W T, Beck
Publikováno v: Oncology research. 4(11-12)
In an attempt to characterize and overcome tumor cell resistance to amsacrine (m-AMSA), we studied the structure-activity relationships for amsacrine and seven of its analogs. Using the human leukemic cell line, CCRF-CEM, and its derivatives that exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::250cc279f326b169fae8443181d9b85d
https://pubmed.ncbi.nlm.nih.gov/1363724
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6
Thermodynamic Studies of Amsacrine Antitumor Agents with Nucleic Acids
Autor: R. M. Wadkins, D. E. Graves
Publikováno v: The Jerusalem Symposia on Quantum Chemistry and Biochemistry ISBN: 9789401056571
The equilibrium binding of several anilinoacridine analogs are compared over a wide range of ionic strengths and temperatures. Although o-AMSA binds DNA with a higher affinity than m-AMSA it is not effective as an antitumor agent. Both m-AMSA and o-A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8429bad5759f09f4626e6d21add32602
https://doi.org/10.1007/978-94-011-3728-7_13
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9
High-kilovoltage radiography
Autor: D. B. Slauson, E. Dale Trout, D. E. Graves
Publikováno v: Radiology. 52(5)
LIKE THE OTHER factors involved in radiography, the kilovoltage factor has been the subject of almost continuous study. The equipment available has always had a profound influence on the voltage range over which routine work could be done. At no time
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4349d841ce10f11a050515f0a5dc5f2a
https://pubmed.ncbi.nlm.nih.gov/18120467
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