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The Impact of Heat-Not-Burn, E-Cigarettes, and Cigarettes on Small Airway Function

Autor: L. Jung, I. C. Buchwald, A. Hauck, M. Lüthgen, T. Jagomast, M. Weckmann, D. Drömann, K. F. Franzen

Publikováno v: Tobacco Use Insights, Vol 17 (2024)

Introduction E-cigarettes and heated tobacco products (HTPs) are gaining worldwide significance. The tobacco industry is promoting these products as healthier alternatives to conventional cigarettes. Methods In this four-arm crossover study, we exami

Externí odkaz: https://doaj.org/article/951042e6cc8543a18e3e1d1aab936793

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Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial

Autor: Marius M Hoeper, Hikmet Al-Hiti, Raymond L Benza, Sung-A Chang, Paul A Corris, J Simon R Gibbs, Ekkehard Grünig, Pavel Jansa, James R Klinger, David Langleben, Vallerie V McLaughlin, Gisela M B Meyer, Jaquelina Ota-Arakaki, Andrew J Peacock, Tomás Pulido, Stephan Rosenkranz, Carmine Dario Vizza, Anton Vonk-Noordegraaf, R James White, Mikyung Chang, Frank Kleinjung, Christian Meier, Karen Paraschin, Hossein Ardeschir Ghofrani, Gérald Simonneau, H Olschewski, M Delcroix, M Andrade-Lima, R de Amorim Corrêac, F Figueiredo Campos, J Ota Arakaki, G Meyer, R De Souza, D Langleben, H Al-Hiti, P Jansa, S Mellemkjær, F Bauer, D Montani, G Simonneau, D Drömann, H-A Ghofrani, E Grünig, M Halank, M Held, MM Hoeper, H Klose, N Kneidinger, H Leuchte, C Opitz, S Rosenkranz, H Wilkens, H Wirtz, H Karvounis, G Pitsiou, S Orfanos, M D'Alto, S Ghio, CD Vizza, P Vitulo, T Nakayama, H Maki, S Tatebe, M de los Rios Ibarra, T Pulido, A Van Dijk, A Vonk-Noordegraaf, T Roleder, G Castro, MJ Loureiro, S Robalo-Martins, JA Barberá, M Lázaro, GM Perez-Penate, A Román, C-C Cheng, C-H Hsu, H-H Hsu, E Atahan, N Mogulkoc Bishop, NG Okumus, Z Onen, H-J Chang, S-A Chang, J-S Lee, H-K Kim, JG Coghlan, PA Corris, AC Church, R Condliffe, JSR Gibbs, AJ Peacock, S Wort, R Allen, S Allen, R Awdish, RL Benza, S DeSouza, J Feldman, S Johri, JR Klinger, D Layish, J McConnell, VV McLaughlin, C Migliore, F Rahaghi, F Rischard, I Robbins, L Satterwhite, T Shah, R Sulica, RJ White

Publikováno v: The Lancet Respiratory Medicine, 9(6), 573-584. Elsevier Limited
Hoeper, M M, Al-Hiti, H, Benza, R L, Chang, S-A, Corris, P A, Gibbs, J S R, Grünig, E, Jansa, P, Klinger, J R, Langleben, D, McLaughlin, V V, Meyer, G M B, Ota-Arakaki, J, Peacock, A J, Pulido, T, Rosenkranz, S, Vizza, C D, Vonk-Noordegraaf, A, White, R J, Chang, M, Kleinjung, F, Meier, C, Paraschin, K, Ghofrani, H A, Simonneau, G & The REPLACE investigators 2021, ' Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE) : a multicentre, open-label, randomised controlled trial ', The Lancet Respiratory Medicine, vol. 9, no. 6, pp. 573-584 . https://doi.org/10.1016/S2213-2600(20)30532-4
REPLACE investigators 2021, ' Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial ', The Lancet Respiratory Medicine, vol. 9, no. 6, pp. 573-584 . https://doi.org/10.1016/S2213-2600(20)30532-4

BACKGROUND: Riociguat and phosphodiesterase-5 inhibitors (PDE5i), approved for the treatment of pulmonary arterial hypertension (PAH), act on the same pathway via different mechanisms. Riociguat might be an alternative option for patients with PAH wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56129be8d7d9bbfecf556d9b7ae7f504
https://research.vumc.nl/en/publications/422b5ce8-53f9-4f2f-8e03-8a80ae3dd2b8

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