Risk Factors, Treatments, and Outcomes of Adults Aged

Autor: Tolga D. Dittrich, Thomas Schneider, Mira Katan, Andreas R. Luft, Marie‐Luise Mono, Manuel Bolognese, Krassen Nedeltchev, Timo Kahles, Marcel Arnold, Mirjam Heldner, Patrik Michel, Emmanuel Carrera, Biljana Rodic, Carlo W. Cereda, Nils Peters, Leo H. Bonati, Susanne Renaud, Andrea M. Humm, Friedrich Medlin, Sylvan Albert, Rolf Sturzenegger, Alexander A. Tarnutzer, Philip Siebel, Markus Baumgärtner, Christian Berger, Pasquale Mordasini, Jochen Vehoff, Gian Marco De Marchis

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 23 (2024)

Background The rising prevalence of acute ischemic stroke (AIS) in young adults, particularly with undetermined pathogenesis, is a growing concern. This study assessed risk factors, treatments, and outcomes between young AIS patients with undetermine

Externí odkaz: https://doaj.org/article/dbc4a8ec54a14f05b0a82019a0cbde63

Lipoprotein(a) as a blood marker for large artery atherosclerosis stroke etiology: validation in a prospective cohort from a swiss stroke center

Autor: Salome Rudin, Lilian Kriemler, Tolga D. Dittrich, Annaelle Zietz, Juliane Schweizer, Markus Arnold, Nils Peters, Filip Barinka, Simon Jung, Marcel Arnold, Katharina Rentsch, Mirjam Christ-Crain, Mira Katan, Gian Marco De Marchis

Publikováno v: Swiss Medical Weekly, Vol 154, Iss 4 (2024)

BACKGROUND: Lipoprotein (a) [Lp(a)] serum levels are highly genetically determined and promote atherogenesis. High Lp(a) levels are associated with increased cardiovascular morbidity. Serum Lp(a) levels have recently been associated with large artery

Externí odkaz: https://doaj.org/article/73ea661fe01d4fb3bb7e6aa3f2db59d1

Impact of type of oral anticoagulants in patients with cerebral microbleeds after atrial fibrillation-related ischemic stroke or TIA: Results of the NOACISP-LONGTERM registry

Autor: Benjamin Wagner, Lisa Hert, Alexandros A. Polymeris, Sabine Schaedelin, Johanna M. Lieb, David J. Seiffge, Christopher Traenka, Sebastian Thilemann, Joachim Fladt, Valerian L. Altersberger, Annaelle Zietz, Tolga D. Dittrich, Urs Fisch, Henrik Gensicke, Gian Marco De Marchis, Leo H. Bonati, Philippe A. Lyrer, Stefan T. Engelter, Nils Peters

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

BackgroundCerebral microbleeds (CMBs) may have a differential impact on clinical outcome in stroke patients with atrial fibrillation (AF) treated with different types of oral anticoagulation (OAC).MethodsObservational single-center study on AF-stroke

Externí odkaz: https://doaj.org/article/5116b2ca04544fe89ea82f88d4e3ec99

Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke

Autor: Gian Marco De Marchis, Tolga D. Dittrich, Rainer Malik, Annaelle V. Zietz, Lilian F. Kriemler, Brian A. Ference, Martin Dichgans, Marios K. Georgakis

Publikováno v: Atherosclerosis. 361:41-46

Post hoc analyses of clinical trials show that PCSK9 inhibitors might lower lipoprotein(a), but whether this effect contributes to reductions in cardiovascular risk remains unknown. We aimed to assess whether genetically proxied PCSK9 inhibition infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f7e007c5503457b3fc1ca8e6b454fb
https://doi.org/10.1016/j.atherosclerosis.2022.09.007

Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial

Autor: Melinda B Roaldsen, Agnethe Eltoft, Tom Wilsgaard, Hanne Christensen, Stefan T Engelter, Bent Indredavik, Dalius Jatužis, Guntis Karelis, Janika Kõrv, Erik Lundström, Jesper Petersson, Jukka Putaala, Mary-Helen Søyland, Arnstein Tveiten, Andrew Bivard, Stein Harald Johnsen, Michael V Mazya, David J Werring, Teddy Y Wu, Gian Marco De Marchis, Thompson G Robinson, Ellisiv B Mathiesen, M Parson, M Valente, A Chen, A Sharobeam, L Edwards, C Blair, L Christensen, K Ægidius, T Pihl, C Fassel-Larsen, L Wassvik, M Folke, S Rosenbaum, S S Gharehbagh, A Hansen, N Preisler, K Antsov, S Mallene, M Lill, M Herodes, R Vibo, A Rakitin, J Saarinen, M Tiainen, O Tumpula, T Noppari, S Raty, G Sibolt, J Nieminen, J Niederhauser, I Haritoncenko, J Puustinen, T-M Haula, J Sipilä, B Viesulaite, S Taroza, D Rastenyte, V Matijosaitis, A Vilionskis, R Masiliunas, A Ekkert, P Chmeliauskas, V Lukosaitis, A Reichenbach, T T Moss, H Y Nilsen, R Hammer-Berntzen, L M Nordby, T A Weiby, K Nordengen, H Ihle-Hansen, M Stankiewiecz, O Grotle, M Nes, K Thiemann, I M Særvold, M Fraas, S Størdahl, J W Horn, H Hildrum, C Myrstad, H Tobro, J-A Tunvold, O Jacobsen, N Aamodt, H Baisa, V N Malmberg, G Rohweder, H Ellekjær, F Ildstad, E Egstad, B H Helleberg, H H Berg, J Jørgensen, E Tronvik, M Shirzadi, R Solhoff, R Van Lessen, A Vatne, K Forselv, H Frøyshov, M S Fjeldstad, L Tangen, S Matapour, K Kindberg, C Johannessen, M Rist, I Mathisen, T Nyrnes, A Haavik, G Toverud, K Aakvik, M Larsson, K Ytrehus, S Ingebrigtsen, T Stokmo, C Helander, I C Larsen, T O Solberg, Y M Seljeseth, S Maini, I Bersås, J Mathé, E Rooth, A-C Laska, A-S Rudberg, M Esbjörnsson, F Andler, A Ericsson, O Wickberg, J-E Karlsson, P Redfors, K Jood, F Buchwald, K Mansson, O Gråhamn, K Sjölin, E Lindvall, Å Cidh, A Tolf, O Fasth, B Hedström, J Fladt, T D Dittrich, L Kriemler, N Hannon, E Amis, S Finlay, J Mitchell-Douglas, J McGee, R Davies, V Johnson, A Nair, M Robinson, J Greig, O Halse, P Wilding, S Mashate, K Chatterjee, M Martin, S Leason, J Roberts, D Dutta, D Ward, R Rayessa, E Clarkson, J Teo, C Ho, S Conway, M Aissa, V Papavasileiou, S Fry, D Waugh, J Britton, A Hassan, L Manning, S Khan, A Asaipillai, C Fornolles, M L Tate, S Chenna, T Anjum, D Karunatilake, J Foot, L VanPelt, A Shetty, G Wilkes, A Buck, B Jackson, L Fleming, M Carpenter, L Jackson, A Needle, T Zahoor, T Duraisami, K Northcott, J Kubie, A Bowring, S Keenan, D Mackle, T England, B Rushton, A Hedstrom, S Amlani, R Evans, G Muddegowda, A Remegoso, P Ferdinand, R Varquez, M Davis, E Elkin, R Seal, M Fawcett, C Gradwell, C Travers, B Atkinson, S Woodward, L Giraldo, J Byers, B Cheripelli, S Lee, R Marigold, S Smith, L Zhang, R Ghatala, C H Sim, U Ghani, K Yates, S Obarey, M Willmot, K Ahlquist, M Bates, K Rashed, S Board, G Andsberg, S Sundayi, M Garside, M-J Macleod, A Manoj, O Hopper, B Cederin, T Toomsoo, K Gross-Paju, T Tapiola, J Kestutis, K-F Amthor, B Heermann, V Ottesen, T A Melum, M Kurz, M Parsons

Publikováno v: The Lancet. Neurology.

Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77e948b8214830b257c18297ff5e11d
https://pubmed.ncbi.nlm.nih.gov/36549308