Zobrazeno 1 - 10 of 205 pro vyhledávání: '"D. D. RICHMAN"'
1
Resting cerebral blood flow: A potential biomarker of the effects of HIV in the brain
Autor: B M, Ances, D, Sisti, F, Vaida, C L, Liang, O, Leontiev, J E, Perthen, R B, Buxton, D, Benson, D M, Smith, S J, Little, D D, Richman, D J, Moore, R J, Ellis, Florin, Vaida
Publikováno v: Ances, BM; Sisti, D; Vaida, F; Liang, CL; Leontiev, O; Perthen, JE; et al.(2009). Resting cerebral blood flow: A potential biomarker of the effects of HIV in the brain. Neurology, 73(9), 702-708. doi: 10.1212/WNL.0b013e3181b59a97. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/20812252
Objective: HIV enters the brain soon after infection causing neuronal damage and microglial/astrocyte dysfunction leading to neuropsychological impairment. We examined the impact of HIV on resting cerebral blood flow (rCBF) within the lenticular nucl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681e0a7e87fac3b8c744e788ecd7f79c
https://doi.org/10.1212/wnl.0b013e3181b59a97
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2
A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A
Autor: L Blystone, D Pillay, Karen E. Potts, Martin L. Bryant, Simon P. Tucker, W. C. Stallings, Mary Smidt, T. R. Stiebel, D D Richman, Joseph J. McDonald
Publikováno v: Antimicrobial Agents and Chemotherapy. 41:515-522
The hydroxyethylurea human immunodeficiency virus type 1 (HIV-1) protease inhibitors SC-55389A and SC-52151 were used to select drug-resistant variants in vitro. One clinical HIV-1 strain (89-959) and one laboratory HIV-1 strain (LAI) were passaged i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16db6aa83e299a33a5a2349b4c436df3
https://doi.org/10.1128/aac.41.3.515
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3
Association of Plasma Human Immunodeficiency Virus Type 1 RNA Level withRisk of Clinical Progression in Patients with Advanced Infection
Autor: Clyde S. Crumpacker, A. J. Japour, S. Kwok, James O. Kahn, Daniel R. Kuritzkes, Victor DeGruttola, J. B. Jackson, V. A. Johnson, John Todd, P. S. Reichelderfer, Carol J. Hooper, D. D. Richman, S. L. Welles, Robert W. Coombs, Richard T. D'Aquila
Publikováno v: Journal of Infectious Diseases. 174:704-712
Human immunodeficiency virus (HIV)-1 RNA level in plasma was evaluated as a surrogate marker for disease progression in a clinical trial of advanced HIV-1 infection. Baseline HIV-1 RNA level was an independent predictor of disease progression (relati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa4a065200b688429611af244bb2b14f
https://doi.org/10.1093/infdis/174.4.704
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5
Prevalence and Clinical Significance of Zidovudine Resistance Mutations in Human Immunodeficiency Virus Isolated from Patients after Long-Term Zidovudine Treatment
Autor: Patricia Reichelderfer, Seth L. Welles, Daniel R. Kuritzkes, A. J. Japour, James O. Kahn, D. D. Richman, Richard T. D'Aquila, Robert W. Coombs, Victoria A. Johnson, Clyde S. Crumpacker
Publikováno v: Journal of Infectious Diseases. 171:1172-1179
Zidovudine resistance mutations at reverse transcriptase codons 215 or 41 were found in two-thirds of human immunodeficiency virus type 1 (HIV-1) isolates obtained at baseline from patients enrolled in an AIDS Clinical Trials Group (ACTG) protocol th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0aacc421d54765c0408f4ec8367850c2
https://doi.org/10.1093/infdis/171.5.1172
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6
2-LTR Circular Viral DNA as a Marker for Human Immunodeficiency Virus Type 1 Infection in Vivo
Autor: C. D. Pauza, F. M. Graziano, Parul Trivedi, T. S. Mckechnie, D. D. Richman
Publikováno v: Virology. 205:470-478
The unintegrated viral DNA found in human immunodeficiency virus type 1 infection includes linear and circular forms. We targeted the circular form containing two copies of the viral long terminal repeat (2-LTR circle) and developed specific assays t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626336f42dc0491407f7c0781462feca
https://doi.org/10.1006/viro.1994.1667
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8
Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells
Autor: J Galindo, D D Richman, C D Pauza
Publikováno v: The Journal of Experimental Medicine
High levels of unintegrated viral DNA accumulate during human immunodeficiency virus type 1 (HIV-1) infection of CEM T cells. Reinfection of already infected cells is required to attain these levels and reinfection also promotes the development of HI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3ab79ba1dae2d8dda69ef2855c8607
https://doi.org/10.1084/jem.172.4.1035
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10
Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network
Autor: E S, Daar, S, Little, J, Pitt, J, Santangelo, P, Ho, N, Harawa, P, Kerndt, J V, Glorgi, J, Bai, P, Gaut, D D, Richman, S, Mandel, S, Nichols
Publikováno v: Annals of internal medicine. 134(1)
The optimal approach for diagnosing primary HIV-1 infection has not been defined.To determine the usefulness of symptoms and virologic tests for diagnosing primary HIV-1 infection.Prospective cohort study.A teaching hospital in Los Angeles and a univ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::614f492f67e167f1e32fd510d30294db
https://pubmed.ncbi.nlm.nih.gov/11900505
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