Zobrazeno 1 - 10
of 110
pro vyhledávání: '"D. D. Heistad"'
Autor:
Lars Edvinsson, Frank M. Faraci, D. D. Heistad, William W. Gierasch, Penny X. Dong, Kevin T. Belasco, Jeffrey Kasperski, Andrew F. Russo, Paul L. Durham
Publikováno v:
Brain Research. 997:103-110
We have examined the regulation of calcitonin gene-related peptide (CGRP) promoter activity in primary cultures of rat trigeminal ganglia neurons. A viral vector was used to circumvent the potential complication of examining only a small subpopulatio
Autor:
D. D. Heistad, Frank M. Faraci
Publikováno v:
Physiological Reviews. 78:53-97
Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998. — Several new concepts have emerged in relation to mechanisms that contribute to regulatio
Publikováno v:
Hypertension. 30:708-713
Abstract Baroreceptor nerve endings are located in the adventitia of the carotid sinuses and aortic arch. The goal of the present study was to develop a method for gene transfer to the carotid sinus adventitia. Replication-deficient adenovirus contai
Autor:
D D Heistad, J K Williams
Publikováno v:
Trends in Cardiovascular Medicine. 6:53-57
Vasa vasorum provide an important source of nutrition to arteries and veins. In normal arteries, vasa vasorum from the adventitia grow into the media of large arteries and veins and actively regulate blood flow to the wall of these vessels. In athero
Publikováno v:
Stroke. 23:1494-1498
Diabetes mellitus may impair endothelium-dependent responses in cerebral arterioles. The basilar artery dilates in response to increases in blood flow. The goal of this study was to examine effects of diabetes mellitus on "flow-mediated" and endothel
Autor:
Andreas Mügge, D. P. Piegors, Mark L. Armstrong, D. D. Heistad, R. C. Padgett, J. A. G. Lopez
Publikováno v:
Circulation Research. 70:423-429
Activation of leukocytes in vivo produces marked constriction of large arteries in atherosclerotic, but not in normal, monkeys. We tested the hypotheses that vasoconstrictor responses to activated leukocytes in vivo may be abnormal during hypercholes
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 261:H707-H713
We used the microsphere technique and laser flowmetry to assess cerebral blood flow in 43 anesthetized rats. Cerebral blood flow did not increase significantly when the fastigial nucleus was stimulated 15 min after administration of alpha-chloralose.
Publikováno v:
Stroke. 22:763-767
Large arteries contribute to the regulation of cerebral blood flow. The goal of this study was to examine the effects of changes in diameter of the basilar artery on blood flow to the brain stem. We measured blood flow with laser-Doppler flowmetry in
Publikováno v:
Acta neurochirurgica. Supplement. 104
This mini-review describes steps towards gene therapy to prevent vasospasm after subarachnoid hemorrhage, and summarizes some remaining obstacles. With recombinant adenoviruses, it is now possible to prevent vasospasm in experimental animals. If an a
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 258:H1138-H1143
Our goal was to determine whether responses of cerebral arterioles are altered in aged rats. We examined responses of cerebral arterioles in adult (6-8 mo old) and aged (22-24) mo old) Wistar rats to superfusion of acetylcholine and bradykinin, which