Zobrazeno 1 - 10
of 899
pro vyhledávání: '"D. Cosgrove"'
Autor:
Andrea Flesken-Nikitin, Coulter Q. Ralston, Dah-Jiun Fu, Andrea J. De Micheli, Daryl J. Phuong, Blaine A. Harlan, Christopher S. Ashe, Amanda P. Armstrong, David W. McKellar, Sangeeta Ghuwalewala, Lora H. Ellenson, John C. Schimenti, Benjamin D. Cosgrove, Alexander Yu. Nikitin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The distal region of the uterine (Fallopian) tube is commonly associated with high-grade serous carcinoma (HGSC), the predominant and most aggressive form of ovarian or extra-uterine cancer. Specific cell states and lineage dynamics of the a
Externí odkaz:
https://doaj.org/article/90512a4f897946e0b160380da2b3bd0c
Autor:
Erik P. Storrs, Prathamesh Chati, Abul Usmani, Ian Sloan, Bradley A. Krasnick, Ramandeep Babbra, Peter K. Harris, Chloe M. Sachs, Faridi Qaium, Deyali Chatterjee, Chris Wetzel, S. Peter Goedegebuure, Thomas Hollander, Hephzibah Anthony, Jennifer Ponce, Ateeq M. Khaliq, Shahed Badiyan, Hyun Kim, David G. Denardo, Gabriel D. Lang, Natalie D. Cosgrove, Vladimir M. Kushnir, Dayna S. Early, Ashiq Masood, Kian-Huat Lim, William G. Hawkins, Li Ding, Ryan C. Fields, Koushik K. Das, Aadel A. Chaudhuri
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Numerous cell states are known to comprise the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME). However, the developmental stemness and co-occurrence of these cell states remain poorly defined. Here, we performed single-
Externí odkaz:
https://doaj.org/article/903543a9685a4ed99c96f10cecf7b517
Autor:
Alessandra M. Norris, Ambili Bai Appu, Connor D. Johnson, Lylybell Y. Zhou, David W. McKellar, Marie-Ange Renault, David Hammers, Benjamin D. Cosgrove, Daniel Kopinke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Successful muscle regeneration relies on the interplay of multiple cell populations. However, the signals required for this coordinated intercellular crosstalk remain largely unknown. Here, we describe how the Hedgehog (Hh) signaling pathway
Externí odkaz:
https://doaj.org/article/e825d6420a8846a289d38a1d5eb31866
Autor:
Dah-Jiun Fu, Andrea J. De Micheli, Blaine A. Harlan, Mallikarjun Bidarimath, Lora H. Ellenson, Benjamin D. Cosgrove, Andrea Flesken-Nikitin, Alexander Yu. Nikitin
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/5a74e5f4b99348fba6cff2da4c9d74bf
Autor:
David W. McKellar, Lauren D. Walter, Leo T. Song, Madhav Mantri, Michael F. Z. Wang, Iwijn De Vlaminck, Benjamin D. Cosgrove
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
David McKellar et al. integrate single-cell and -nuclear transcriptomic analyses of mouse skeletal muscle in homeostatic conditions or following injury. The resulting transcriptomic model of myogenesis identified rare, transitional states and cell su
Externí odkaz:
https://doaj.org/article/c4f3d62d830e41acb90880a9b21a949c
Autor:
Umji Lee, Pascal Stuelsatz, Sonia Karaz, David W. McKellar, Julie Russeil, Maria Deak, Iwijn De Vlaminck, Christoph Lepper, Bart Deplancke, Benjamin D. Cosgrove, Jerome N. Feige
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104589- (2022)
Summary: Apelin (Apln) is a myokine that regulates skeletal muscle plasticity and metabolism and declines during aging. Through a yeast one-hybrid transcription factor binding screen, we identified the TEA domain transcription factor 1 (Tead1) as a n
Externí odkaz:
https://doaj.org/article/5b78ad39c82e4e3080f88739f302cb31
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Single-cell RNA-sequencing (scRNA-seq) facilitates the unbiased reconstruction of multicellular tissue systems in health and disease. Here, we present a curated scRNA-seq dataset of human muscle samples from 10 adult donors with diverse anat
Externí odkaz:
https://doaj.org/article/19cbd75a7d164cfbba27056c419fc5d1
Autor:
Monique E. Francois, Samuel D. Cosgrove, Nicole M. Walker, Samuel JE. Lucas, Katherine E. Black
Publikováno v:
Journal of Exercise Science & Fitness, Vol 16, Iss 3, Pp 78-82 (2018)
Background/Objective: Adventure racing is an ultra-endurance activity that imposes a unique multifaceted stress on the human body. The purpose of this field study was to examine the physiological responses to a 5-day adventure race. Methods: Eight co
Externí odkaz:
https://doaj.org/article/c4edf10a7ff8475191681c17875056d6
Autor:
Shivem B. Shah, Christopher R. Carlson, Kristine Lai, Zhe Zhong, Grazia Marsico, Katherine M. Lee, Nicole E. Félix Vélez, Elisabeth B. Abeles, Mayar Allam, Thomas Hu, Lauren D. Walter, Karen E. Martin, Khanjan Gandhi, Scott D. Butler, Rishi Puri, Angela L. McCleary-Wheeler, Wayne Tam, Olivier Elemento, Katsuyoshi Takata, Christian Steidl, David W. Scott, Lorena Fontan, Hideki Ueno, Benjamin D. Cosgrove, Giorgio Inghirami, Andrés J. García, Ahmet F. Coskun, Jean L. Koff, Ari Melnick, Ankur Singh
Publikováno v:
Nature Materials. 22:511-523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437c365c91fd56ca70ff4d85310517bf
https://doi.org/10.1038/s41563-023-01495-3
https://doi.org/10.1038/s41563-023-01495-3
Autor:
Dah-Jiun Fu, Andrea J. De Micheli, Mallikarjun Bidarimath, Lora H. Ellenson, Benjamin D. Cosgrove, Andrea Flesken-Nikitin, Alexander Yu. Nikitin
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 10 (2020)
Humans and mice have cyclical regeneration of the endometrial epithelium. It is expected that such regeneration is ensured by tissue stem cells, but their location and hierarchy remain debatable. A number of recent studies have suggested the presence
Externí odkaz:
https://doaj.org/article/371ff2ddb7c04827ae1de1664a9a50c3