Phase I combination study of trabectedin (T) and capecitabine (C) in patients with advanced malignancies

Autor: Scott N. Holden, D. Cleere, Y. A. Elsayed, S. Grolnic, K. Lavallee, S. G. Eckhardt, S. L. Moulder, E. Rivera, Lia Gore

Publikováno v: Journal of Clinical Oncology. 24:2079-2079

2079 Background: T binds to the minor groove of DNA, synergizes with functional nuclease excision repair and targets inducible transcription. T is active in several tumor types and exhibits preclinical synergy with C. The primary objective of this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::051333b28b921d00929e057a03aa3591
https://doi.org/10.1200/jco.2006.24.18_suppl.2079

Training robust T1-weighted magnetic resonance imaging liver segmentation models using ensembles of datasets with different contrast protocols and liver disease etiologies.

Autor: Patel N; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Celaya A; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Computational Applied Mathematics and Operations Research, Rice University, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Eltaher M; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Glenn R; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Savannah KB; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Brock KK; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Sanchez JI; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Calderone TL; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Cleere D; Department of Gastroenterology, Houston Methodist Hospital, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Elsaiey A; Department of Gastroenterology, Houston Methodist Hospital, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Cagley M; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gupta N; Department of Radiology, Houston Methodist Hospital, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Victor D; Department of Gastroenterology, Houston Methodist Hospital, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Beretta L; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Koay EJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Netherton TJ; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. TNetherton@mdanderson.org.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. TNetherton@mdanderson.org., Fuentes DT; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. DTFuentes@mdanderson.org.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. DTFuentes@mdanderson.org.

Publikováno v: Scientific reports [Sci Rep] 2024 Sep 09; Vol. 14 (1), pp. 20988. Date of Electronic Publication: 2024 Sep 09.