Výsledky vyhledávání - "D. Chuck Dunbar"

Antiparasitic, nematicidal and antifouling constituents fromJuniperusberries

Autor: Babu L. Tekwani, Jan Pieter Hendrik Bosselaers, Shabana I. Khan, Md. Abdul Gafur, Jaber S. Mossa, Farouk S. El-Feraly, Volodymyr Samoylenko, D. Chuck Dunbar, Ilias Muhammad, Samir A. Ross

Publikováno v: Phytotherapy Research. 22:1570-1576

A bioassay-guided fractionation of Juniperus procera berries yielded antiparasitic, nematicidal and antifouling constituents, including a wide range of known abietane, pimarane and labdane diterpenes. Among these, abieta-7,13-diene (1) demonstrated i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8440dd7e5f84d1e6954db3238d347fc
https://doi.org/10.1002/ptr.2460

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Batzelladine alkaloids from the caribbean sponge Monanchora unguifera and the significant activities against HIV-1 and AIDS opportunistic infectious pathogens

Autor: Jiangnan Peng, Michelle Kelly, Luis F. Garcia-Fernandez, Arcadio G. de Castro Andrews, Mark T. Hamann, Hui-ming Hua, D. Chuck Dunbar, Carmen Cuevas, Raymond F. Schinazi

Publikováno v: Tetrahedron. 63:11179-11188

Five new polycyclic guanidine alkaloids, 16β-hydroxycrambescidin 359 (1), batzelladines K, L, M, and N (2–5), along with the previously reported ptilomycalin A (6), crambescidine 800 (7), batzelladine C (8), and dehydrobatzelladine C (9), were iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7af5f7fc9cc8ec59dcdce41e46466b2c
https://doi.org/10.1016/j.tet.2007.08.005

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Picric Acid Degradation in Sediments from the Louisiana Army Ammunition Plant

Autor: Gregg R. Davidson, Danny W. Harrelson, Chun Hwa See, Stephanie Rice, D. Chuck Dunbar, Yongqiang Tan, John H. O'Haver, Mansour Zakikhani

Publikováno v: Water, Air, and Soil Pollution. 177:169-181

Picric acid is an explosive historically produced and disposed at the Louisiana Army Ammunition Plant (LAAP) in northern Louisiana. The potential for natural degradation of picric acid was investigated by creating picric-acid slurries with four LAAP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b30bd4e4268cd89f4028c8f9498e1694
https://doi.org/10.1007/s11270-006-9133-y

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New Constituents from Noni (Morinda citrifolia) Fruit Juice

Autor: Volodymyr Samoylenko, D. Chuck Dunbar, James W Rushing, Jianping Zhao, Ilias Muhammad, Ikhlas A. Khan

Publikováno v: Journal of Agricultural and Food Chemistry. 54:6398-6402

Morinda citrifolia L. (Rubiaceae), known as noni, has a long history of traditional use in the Hawaiian and Tahitian islands. More recently, an array of commercial noni fruit juice products are gaining popularity as dietary supplements, with claims o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f8c5214c760fcff20e9eb308230331
https://doi.org/10.1021/jf060672u

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Terpenoid Tetrahydroisoquinoline Alkaloids Emetine, Klugine, and Isocephaeline Inhibit the Activation of Hypoxia-Inducible Factor-1 in Breast Tumor Cells

Autor: Dale G. Nagle, Yong-Pil Kim, Deborah K. Jones, Kaleem A. Mohammed, D. Chuck Dunbar, Ilias Muhammad, Yu-Dong Zhou

Publikováno v: Journal of Natural Products. 68:947-950

Klugine (1), isocephaeline (2), and emetine (4) inhibited hypoxia-inducible factor-1 (HIF-1) activation by hypoxia in T47D breast tumor cells (IC(50) values 0.2, 1.1, and 0.11 muM, respectively). Compounds 1, 2, and 4 inhibited both hypoxia- and iron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77c7980e25fbd113e18382ef93a0d43a
https://doi.org/10.1021/np050029m

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Antiparasitic Alkaloids from Psychotria klugii

Autor: Shabana I. Khan, Ilias Muhammad, D. Chuck Dunbar, Satoshi Takamatsu, Babu L. Tekwani, Erdal Bedir, Daneel Ferreira, Larry A. Walker

Publikováno v: Journal of Natural Products. 66:962-967

Psychotria klugii yielded two new benzoquinolizidine alkaloids, klugine (1) and 7'-O-demethylisocephaeline (2), together with the previously known cephaeline (3), isocephaeline (4), and 7-O-methylipecoside (5). The structures and stereochemistry of 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b59cfea349523917d53764911666c
https://doi.org/10.1021/np030086k

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Antimicrobial and Antiparasitic (+)-trans-Hexahydrodibenzopyrans and Analogues from Machaerium multiflorum

Autor: Daneel Ferreira, D. Chuck Dunbar, Xing-Cong Li, Ilias Muhammad, Babu L. Tekwani, Melissa R. Jacob

Publikováno v: Journal of Natural Products. 66:804-809

Machaerium multiflorum yielded two additional new (+)-trans-hexahydrodibenzopyrans (HHDBP's), machaeriol C (1) and machaeriol D (2), and three new 5,6-seco-HHDBP's, machaeridiol A (3), machaeridiol B (4), and machaeridiol C (5). Their structures and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a2e11bdd6e908f76aef51d94477535
https://doi.org/10.1021/np030045o

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Araguspongines K and L, New Bioactive Bis-1-oxaquinolizidine N-Oxide Alkaloids from Red Sea Specimens of Xestospongia exigua

Autor: D. Chuck Dunbar, † Mansour S. Al-Said, Khaled Y. Orabi, Michelle Kelly, Khalid A. El Sayed, Tatsuo Higa, Mark T. Hamann

Publikováno v: Journal of Natural Products. 65:1782-1785

In addition to the previously reported (+)-araguspongine A, (+)-araguspongine C, (+)-araguspongine D, (-)-araguspongine E, and (+)-xestospongin B, two new N-oxide araguspongines, (+)-araguspongine K and (+)-araguspongine L, are described here. Their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8de0025f1ebd6bfe7a529b3f4f04e5
https://doi.org/10.1021/np0202226

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Transformation of lactone to lactam in sarcophine and antimalarial activity of the resulting N-substituted azasarcophines

Autor: D. Chuck Dunbar, Mitchell A. Avery, Yogesh A. Sabnis, Jaber S. Mossa, Mark T. Hamann, Farouk S. El-Feraly, Khalid A. El Sayed, Khaled Y. Orabi

Publikováno v: Tetrahedron. 58:3699-3708

Sarcophine ( 1 ) is a furanocembranoid diterpene first reported from the Red Sea soft coral Sarcophyton glaucum with remarkable yields of up to 3% dry weight. Semisynthetic transformation of the lactone to lactam in sarcophine by reaction with benzyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3192e3bed775280e890d830df00f9891
https://doi.org/10.1016/s0040-4020(02)00330-7

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Investigation of Uña De Gato I. 7-Deoxyloganic acid and 15N NMR spectroscopic studies on pentacyclic oxindole alkaloids from Uncaria tomentosa

Autor: D. Chuck Dunbar, Ikhlas A. Khan, Riaz A. Khan, Markus Ganzera, Ilias Muhammad

Publikováno v: Phytochemistry. 57:781-785

The C-8-( S ) isomer of deoxyloganic acid (7-deoxyloganic acid), together with β-sitosteryl glucoside, five known stereoisomeric pentacyclic oxindole alkaloids and the tetracyclic oxindole isorhyncophylline, were isolated from the inner bark of Unca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff292fafdda9c3aa6cba8f7a5988974
https://doi.org/10.1016/s0031-9422(01)00043-7

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