Zobrazeno 1 - 10
of 569
pro vyhledávání: '"D. Chien"'
Autor:
Hannah W. Song, Mehdi Benzaoui, Alka Dwivedi, Sarah Underwood, Lipei Shao, Sooraj Achar, Vesna Posarac, Victoria A. Remley, Michaela Prochazkova, Yihua Cai, Ping Jin, Robert P. Somerville, David F. Stroncek, Grégoire Altan-Bonnet, Nirali N. Shah, Christopher D. Chien, Naomi Taylor, Steven L. Highfill
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101171- (2024)
Chimeric antigen receptor T cells (CART) have demonstrated curative potential for hematological malignancies, but the optimal manufacturing has not yet been determined and may differ across products. The first step, T cell selection, removes contamin
Externí odkaz:
https://doaj.org/article/e203f324125d46899b74298138fef026
Autor:
Markus Flatken, Artur Podobas, Riccardo Fellegara, Achim Basermann, Johannes Holke, David Knapp, Max Kontak, Christian Krullikowski, Michael Nolde, Nick Brown, Rupert Nash, Gordon Gibb, Evgenij Belikov, Steven W. D. Chien, Stefano Markidis, Pierre Guillou, Julien Tierny, Jules Vidal, Charles Gueunet, Johannes Gunther, Miroslaw Pawlowski, Piero Poletti, Giorgio Guzzetta, Mattia Manica, Agnese Zardini, Jean-Pierre Chaboureau, Miguel Mendes, Adrian Cardil, Santiago Monedero, Joaquin Ramirez, Andreas Gerndt
Publikováno v:
IEEE Access, Vol 11, Pp 87805-87834 (2023)
Natural disasters and epidemics are unfortunate recurring events that lead to huge societal and economic loss. Recent advances in supercomputing can facilitate simulations of such scenarios in (or even ahead of) real-time, therefore supporting the de
Externí odkaz:
https://doaj.org/article/8ada4e4b2baa4f3688f17ff48c402082
Autor:
Lisa M. Niswander, Zachary T. Graff, Christopher D. Chien, John A. Chukinas, Christina A. Meadows, Lillie C. Leach, Joseph P. Loftus, M. Eric Kohler, Sarah K. Tasian, Terry J. Fry
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Chimeric antigen receptor (CAR) T-cell immunotherapies targeting CD19 or CD22 induce remissions in the majority of patients with relapsed/refractory B-cell acute lymphoblastic leukemia (ALL), although relapse due to target antigen loss or downregulat
Externí odkaz:
https://doaj.org/article/a5805048705444a4ba59c1b09eba9327
Autor:
Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/7341e3e04ef748e4ab7d4e2752aa2b98
Autor:
Haneen Shalabi, Haiying Qin, Angela Su, Bonnie Yates, Pamela L. Wolters, Seth M. Steinberg, John A. Ligon, Sara Silbert, Kniya DéDé, Mehdi Benzaoui, Sophia Goldberg, Sooraj Achar, Dina Schneider, Shilpa A. Shahani, Lauren Little, Toni Foley, John C. Molina, Sandhya Panch, Crystal L. Mackall, Daniel W. Lee, Christopher D. Chien, Marie Pouzolles, Mark Ahlman, Constance M. Yuan, Hao-Wei Wang, Yanyu Wang, Jon Inglefield, Mary Anne Toledo-Tamula, Staci Martin, Steven L. Highfill, Gregoire Altan-Bonnet, David Stroncek, Terry J. Fry, Naomi Taylor, Nirali N. Shah
Publikováno v:
Blood. 140:451-463
Remission durability following single-antigen targeted chimeric antigen receptor (CAR) T-cells is limited by antigen modulation, which may be overcome with combinatorial targeting. Building upon our experiences targeting CD19 and CD22 in B-cell acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa29724981dfcf02642a4b99ff419c1f
https://doi.org/10.1182/blood.2022015795
https://doi.org/10.1182/blood.2022015795
Autor:
Elad Jacoby, Sang M. Nguyen, Thomas J. Fountaine, Kathryn Welp, Berkley Gryder, Haiying Qin, Yinmeng Yang, Christopher D. Chien, Alix E. Seif, Haiyan Lei, Young K. Song, Javed Khan, Daniel W. Lee, Crystal L. Mackall, Rebecca A. Gardner, Michael C. Jensen, Jack F. Shern, Terry J. Fry
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
CAR-T targeting CD19 have been successfully used in a variety of B-cell malignancies but patients may eventually relapse. Here, the authors show that CD19 CAR-T resistance in pre-B cell ALL can be due to the induction of a myeloid lineage switch thro
Externí odkaz:
https://doaj.org/article/97b2ab47d3724d76ba75fa902257a2ba
Publikováno v:
Proceedings of the 3rd International CoNEXT Student Workshop.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8588634a7bb730e7c4036672f061f0d7
https://doi.org/10.1145/3565477.3569146
https://doi.org/10.1145/3565477.3569146
Autor:
Stefano Markidis, Vyacheslav Olshevsky, Chaitanya Prasad Sishtla, Steven W. D. Chien, Erwin Laure, Giovanni Lapenta
Publikováno v:
Frontiers in Physics, Vol 6 (2018)
Particle-in-Cell (PIC) methods are widely used computational tools for fluid and kinetic plasma modeling. While both the fluid and kinetic PIC approaches have been successfully used to target either kinetic or fluid simulations, little was done to co
Externí odkaz:
https://doaj.org/article/7b64655c938848a084cb7f15ebf7874f
Autor:
E. Felip, D.R. Spigel, O.J. Juan Vidal, J.T. Beck, C. Aguado de la Rosa, D.H. Johnson, E. Spath-Schwalbe, A. Reinacher-Schick, D. Rodriguez Abreu, M. Altan, N. Reinmuth, M.J. Edelman, M. Reck, Q. Zhao, S. Banerjee, S. Chaudhry, D. Chien, M.A. Tagliaferri, J. Zalevsky, A. Ganti
Publikováno v:
Annals of Oncology. 32:S1438-S1440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e0421c1f016a2115b02466d64a7163
https://doi.org/10.1016/j.annonc.2021.10.159
https://doi.org/10.1016/j.annonc.2021.10.159
Publikováno v:
The Journal of Physical Chemistry A. 124:3711-3719
Large mass-independent fractionation signatures in Hg have been observed in the laboratory and the environment, prompting deep questions about the chemical reasons behind these signatures. Since the relative lack of mechanistic information about Hg c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd00c72ac88fba4f2f507638a56bdcbe
https://doi.org/10.1021/acs.jpca.0c00661
https://doi.org/10.1021/acs.jpca.0c00661