Zobrazeno 1 - 10
of 840
pro vyhledávání: '"D. Chevalier"'
Publikováno v:
Journal of European CME, Vol 9, Iss 1 (2020)
A survey of Blackpool Foundation Year One (FY1) doctors found limited training about being on-call. We could not find any direct mention in Tomorrow’s Doctors for preparing undergraduates for this.1 Working out of hours, on-call and with a reduced
Externí odkaz:
https://doaj.org/article/fa6c36acbc6a4dce88000212185f2bb2
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-20 (2024)
Abstract Background The role of pathogen genotype in determining disease severity and immunopathology has been studied intensively in microbial pathogens including bacteria, fungi, protozoa and viruses but is poorly understood in parasitic helminths.
Externí odkaz:
https://doaj.org/article/4e10fc823c6c49ddad7569ac2cabd491
Autor:
Winka Le Clec’h, Frédéric D. Chevalier, Marina McDew-White, Vinay Menon, Grace-Ann Arya, Timothy J.C. Anderson
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1508-1526 (2021)
Both theory and experimental data from pathogens suggest that the production of transmission stages should be strongly associated with virulence, but the genetic bases of parasite transmission/virulence traits are poorly understood. The blood fluke S
Externí odkaz:
https://doaj.org/article/450aff1361ae4c1bb4c6a2fada95e3de
Autor:
Philip T. LoVerde, Sevan N. Alwan, Alexander B. Taylor, Jayce Rhodes, Frédéric D. Chevalier, Timothy Jc Anderson, Stanton F. McHardy
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 18, Iss , Pp 103- (2022)
Externí odkaz:
https://doaj.org/article/db504295d1b64fbdba4f77b5d55ff3c7
Autor:
Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss , Pp 8-15 (2020)
Human schistosomiasis is a disease which globally affects over 229 million people. Three major species affecting humans are Schistosoma mansoni, S. haematobium and S. japonicum. Previous treatment of S. mansoni includes the use of oxamniquine (OXA),
Externí odkaz:
https://doaj.org/article/d86b55a8a7f64c9c9976e5f440e1e224
Autor:
Winka Le Clecʼh, Robbie Diaz, Frédéric D. Chevalier, Marina McDew-White, Timothy J. C. Anderson
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background Parasite traits associated with transmission success, such as the number of infective stages released from the host, are expected to be optimized by natural selection. However, in the trematode parasite Schistosoma mansoni, a key
Externí odkaz:
https://doaj.org/article/2134c2ac88804132a6e02e3fa2d8dc8f
Autor:
Meghan A. Guzman, Anastasia Rugel, Sevan N. Alwan, Reid Tarpley, Alexander B. Taylor, Frédéric D. Chevalier, George R. Wendt, James J. Collins, Timothy J. C. Anderson, Stanton F. McHardy, Philip T. LoVerde
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1416 (2022)
Oxamniquine (OXA) is a prodrug activated by a sulfotransferase (SULT) that was only active against Schistosoma mansoni. We have reengineered OXA to be effective against S. haematobium and S. japonicum. Three derivatives stand out, CIDD-0066790, CIDD-
Externí odkaz:
https://doaj.org/article/e5605799150f4a7ab88576d43918dca9
Publikováno v:
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale. 139:265-272
Publikováno v:
Parasites & Vectors. 16
Background The trematode parasite Schistosoma mansoni uses an aquatic snail intermediate and a vertebrate definitive host to complete its life cycle. We previously showed that a key transmission trait—the number of cercariae larvae shed from infect
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