Zobrazeno 1 - 10
of 115
pro vyhledávání: '"D. Carthy"'
Autor:
Carolyn A Young, C. L. A. Mann, Richard C. Strange, W. E. R. Ollier, M. B. Davies, S. J. M. Weatherby, Mike Boggild, Anthony A. Fryer, D. Carthy, Clive Hawkins
Publikováno v:
Scopus-Elsevier
Allelic variants of the apolipoprotein E (APOE) gene influence the course of several neurological diseases. In multiple sclerosis the concentration of APOE in cerebrospinal fluid and its intrathecal synthesis is reduced. Specific isoforms of APOE may
Akademický článek
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Publikováno v:
Scopus-Elsevier
Previous serological studies of Greek rheumatoid arthritis (RA) patients have failed to demonstrate an association with DR4. Using sequence specific oligonucleotide typing we have identified the DRB1 alleles in panels of Greek RA patients and control
Publikováno v:
International journal of epidemiology. 37
EBV immortalized B lymphocyte cell lines have been extensively used as a source of biological material for functional and molecular studies and represent a potentially limitless source of genomic DNA. Current technologies for EBV transformation are c
Autor:
Taunton R. Southwood, W. E. R. Ollier, L. Holt, A. Farhan, L. Pepper, C. Ryder, D. Carthy, Rachelle Donn, Wendy Thomson
Publikováno v:
British journal of rheumatology. 34(5)
A panel of 43 early onset pauciarticular (EOPA) juvenile chronic arthritis (JCA) patients have been typed for human leucocyte antigens (HLA) DRB1, DPB1, DQA1 alleles, and DQB1*0603 status using molecular-based methods. Increased frequencies of DRB1*0
Autor:
W. E. R. Ollier, Jiri Vencovsky, D. Carthy, S. Bamber, Rizgar A. Mageed, Alex J. MacGregor, Alan J. Silman
Publikováno v:
British journal of rheumatology. 34(3)
The objective of the study was to investigate the genetic contribution to the clinical expression of rheumatoid arthritis (RA) by comparison of disease features in RA-concordant monozygotic (MZ) twin pairs. Fourteen RA-concordant MZ twin pairs recrui
Publikováno v:
Revue du rhumatisme (English ed.). 62(3)
to determine the effect of HLA-DPB1 status on rheumatoid arthritis (RA) susceptibility and disease expression.HLA-DPB1 alleles were identified in 158 RA patients and 106 controls using PCR-sequence specific oligonucleotide probing. HLA-DPB1 allele fr
Publikováno v:
Arthritis and rheumatism. 38(1)
To determine whether an allelic form of mannose-binding protein (MBP) incapable of activating complement is associated with susceptibility to systemic lupus erythematosus (SLE).MBP allele frequencies were determined by amplification refractory mutati
Publikováno v:
Scopus-Elsevier
OBJECTIVES--To assess the association between exposure to parvovirus B19 and susceptibility to rheumatoid arthritis (RA). METHODS--One hundred and fifty five twin pairs (76 monozygotic (MZ) and 79 dizygotic (DZ)), discordant for RA, were tested for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2a4f83e89290d861da5d20b9c097e7
https://europepmc.org/articles/PMC1005267/
https://europepmc.org/articles/PMC1005267/
Autor:
A. Farhan, D. Carthy, Alex J. MacGregor, William E R Ollier, S. Holligan, Wendy Thomson, Alan J. Silman
Publikováno v:
British journal of rheumatology. 32(10)
We report the concordance rate for RA in a nationwide study of 91 monozygotic (MZ) and 112 dizygotic (DZ) pairs. Twin pairs were recruited from both a national media campaign and a 2-month prospective inquiry of all UK rheumatologists. Disease status