Zobrazeno 1 - 10
of 604
pro vyhledávání: '"D. CROWELL"'
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
Autor:
Preston D. Crowell, Jenna M. Giafaglione, Anthony E. Jones, Nicholas M. Nunley, Takao Hashimoto, Amelie M.L. Delcourt, Anton Petcherski, Raag Agrawal, Matthew J. Bernard, Johnny A. Diaz, Kylie Y. Heering, Rong Rong Huang, Jin-Yih Low, Nedas Matulionis, Nora M. Navone, Huihui Ye, Amina Zoubeidi, Heather R. Christofk, Matthew B. Rettig, Robert E. Reiter, Michael C. Haffner, Paul C. Boutros, Orian S. Shirihai, Ajit S. Divakaruni, Andrew S. Goldstein
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113221- (2023)
Summary: Advanced prostate cancers are treated with therapies targeting the androgen receptor (AR) signaling pathway. While many tumors initially respond to AR inhibition, nearly all develop resistance. It is critical to understand how prostate tumor
Externí odkaz:
https://doaj.org/article/918185a092bc44e997b51df4ec5e68c1
Publikováno v:
Frontiers in Earth Science, Vol 10 (2022)
The relationships between clam gardens and human settlement throughout the millennia reflects the inseparable links among human demographics, marine management systems, and the social-ecological contexts in which they are embedded. However, it can be
Externí odkaz:
https://doaj.org/article/6a8c624829fb47c1bdcfa174308548b2
Autor:
David A Castilla-Casadiego, Katherine A Miranda-Muñoz, Jesse L Roberts, Anne D Crowell, David Gonzalez-Nino, Dipankar Choudhury, Frank O Aparicio-Solis, Shannon L Servoss, Adrianne M Rosales, Gary Prinz, Min Zou, Yuntao Zhang, Johann F Coetzee, Lauren F Greenlee, Jeremy Powell, Jorge Almodovar
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272169 (2022)
Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was t
Externí odkaz:
https://doaj.org/article/cbb414d6ce4c4e2981b19efdddd25cef
Autor:
Jack Mottahedeh, Michael C. Haffner, Tristan R. Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs, Srinivasan Yegnasubramanian, Matthew B. Rettig, David A. Elashoff, Elizabeth A. Platz, Angelo M. De Marzo, Michael A. Teitell, Andrew S. Goldstein
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Background Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD+) which is maintained by a balance of NAD+ hydrolase activity and NAD+ salvage activity. We recently reported that human prost
Externí odkaz:
https://doaj.org/article/74edf0c78aa84fd28034f0b9a6de4892
Autor:
Brian E. Lacy, Michael D. Crowell, David J. Cangemi, Tisha N. Lunsford, Magnus Simren, Jan Tack
Publikováno v:
American Journal of Gastroenterology. 116:2345-2356
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 2 (2017)
While chronic inflammation has been causally associated with several epithelial malignancies, whether it causally contributes to the development of prostate cancer has remained unclear. We recently reported that progenitor-like inflammation-associate
Externí odkaz:
https://doaj.org/article/281b0f1cfe7b400a98626ec13418ccf5
Publikováno v:
Gastroenterology Research and Practice, Vol 2017 (2017)
Background. Adenoma detection rate (ADR) is a validated quality measure for screening colonoscopy, but there are little data for other indications. The distribution of adenomas is not well described for these indications. Aim. To describe ADR and the
Externí odkaz:
https://doaj.org/article/fde71fa60bfd4e72b35a00ea18db0809
Publikováno v:
Clinical Gastroenterology and Hepatology. 19:80-86
Background & Aims Irritable bowel syndrome (IBS) is a common chronic functional bowel disorder for which patients take significant risks to ameliorate symptoms. Unfortunately, there is no cure for IBS. We assessed the willingness of patients with IBS
Autor:
Preston D. Crowell, Jenna M. Giafaglione, Anthony E. Jones, Nicholas M. Nunley, Takao Hashimoto, Amelie M.L. Delcourt, Anton Petcherski, Matthew J. Bernard, Rong Rong Huang, Jin-Yih Low, Nedas Matulionis, Xiangnan Guan, Nora M. Navone, Joshi J. Alumkal, Michael C. Haffner, Huihui Ye, Amina Zoubeidi, Heather R. Christofk, Orian S. Shirihai, Ajit S. Divakaruni, Andrew S. Goldstein
Prostate cancer cells that survive clinical androgen receptor (AR) blockade mediate disease progression and lethality. Reprogrammed metabolic signaling is one mechanism by which tumor cells can survive treatment. However, how AR inhibition reprograms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a0067d9d5b6a18243deae560dd4938
https://doi.org/10.1101/2022.05.31.494200
https://doi.org/10.1101/2022.05.31.494200