Zobrazeno 1 - 10
of 26
pro vyhledávání: '"D. C. Wraith"'
Publikováno v:
Immunology. 98:116-122
The ability of T cells from rheumatoid factor (RF)-positive patients with rheumatoid arthritis (RA) to respond to immunoglobulin G (IgG) was assessed. Peripheral blood mononuclear cells (PBMC) from RA patients and normal individuals were cultured wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::982b706e36939e5fca37895880d057b7
https://doi.org/10.1046/j.1365-2567.1999.00852.x
https://doi.org/10.1046/j.1365-2567.1999.00852.x
Publikováno v:
Immunology. 98(1)
The ability of T cells from rheumatoid factor (RF)-positive patients with rheumatoid arthritis (RA) to respond to immunoglobulin G (IgG) was assessed. Peripheral blood mononuclear cells (PBMC) from RA patients and normal individuals were cultured wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa45c1db86390ec2e6ef5abb85b2fa46
https://pubmed.ncbi.nlm.nih.gov/10469242
https://pubmed.ncbi.nlm.nih.gov/10469242
Publikováno v:
European journal of immunology. 29(6)
The use of altered peptide ligands (APL) with TCR antagonist properties holds promise as an antigen-specific therapy for autoimmune disorders. We are investigating the therapeutic potential of APL in experimental autoimmune encephalomyelitis (EAE) us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dac2b498e34a09a6cf32971f4575c139
https://pubmed.ncbi.nlm.nih.gov/10382747
https://pubmed.ncbi.nlm.nih.gov/10382747
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(8)
The CD28/B7 system provides costimulatory signals necessary for optimal T cell activation. We have examined the effects of blocking B7.1 and/or B7.2 in an in vitro system using TCR transgenic T cells specific for myelin basic protein. Activation of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45545df7cb7ac49dcfb775b230f89c70
https://pubmed.ncbi.nlm.nih.gov/9780147
https://pubmed.ncbi.nlm.nih.gov/9780147
Publikováno v:
Novartis Foundation symposium. 215
Antigen-specific tolerance induction is the ultimate goal for specific immunotherapy of autoimmune diseases. Here we will discuss recent experiments designed to induce tolerance following mucosal administration of antigens in a mouse model of experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::113322c709b3b7eab7b8bd00f8c0a79d
https://pubmed.ncbi.nlm.nih.gov/9760575
https://pubmed.ncbi.nlm.nih.gov/9760575
Autor:
S M, Anderton, S P, Manickasingham, C, Burkhart, T A, Luckcuck, S J, Holland, A G, Lamont, D C, Wraith
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(7)
The use of altered peptide ligands (APL) to modulate T cell responses has been suggested as a means of treating T cell-mediated autoimmune disorders. We have assessed the therapeutic potential of TCR antagonist peptides in autoimmunity using murine e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37be0f405dd49ac49ecf2b19b11a7e49
https://pubmed.ncbi.nlm.nih.gov/9759852
https://pubmed.ncbi.nlm.nih.gov/9759852
Publikováno v:
Transplantation. 65(10)
The indirect pathway of allorecognition involves the processing and presentation of donor molecules by recipient antigen-presenting cells to alloreactive CD4+ T cells. Our objective was to assess the occurrence and significance of the indirect presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96e77d7dd716da95b9ec5577405cb265
https://pubmed.ncbi.nlm.nih.gov/9625019
https://pubmed.ncbi.nlm.nih.gov/9625019
Autor:
S M, Anderton, D C, Wraith
Publikováno v:
European journal of immunology. 28(4)
Nasal administration of peptide antigens has been shown to induce T cell tolerance. We have investigated the potential for peptide therapy of the autoimmune response to myelin antigens in experimental autoimmune encephalomyelitis (EAE). Three major e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05409f767feb357ac6db98795f846e06
https://pubmed.ncbi.nlm.nih.gov/9565365
https://pubmed.ncbi.nlm.nih.gov/9565365
Publikováno v:
Transplantation. 64(3)
Antibodies targeting recipient major histocompatibility complex (MHC) class II molecules have been demonstrated to be effective at prolonging allograft survival. However, antigen-presenting cell depletion would explain this effect and has not been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6770537ce56c235bb9610e1657fa8fa3
https://pubmed.ncbi.nlm.nih.gov/9275122
https://pubmed.ncbi.nlm.nih.gov/9275122
Autor:
S, Amor, J K, O'Neill, M M, Morris, R M, Smith, D C, Wraith, N, Groome, P J, Travers, D, Baker
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(8)
Myelin basic protein (MBP) and synthetic MBP peptides were screened for their ability to induce experimental allergic encephalomyelitis in Biozzi ABH (H-2Ag7) mice. In contrast to the failure of native MBP to induce experimental allergic encephalomye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::659a56fe79b49cbfd2fc21c56268ea5d
https://pubmed.ncbi.nlm.nih.gov/8609422
https://pubmed.ncbi.nlm.nih.gov/8609422