Zobrazeno 1 - 10
of 161
pro vyhledávání: '"D. C. Morrison"'
Publikováno v:
The Journal of Immunology. 159:5079-5083
We have investigated the effects of human LPS-binding protein (LBP) and human bactericidal/permeability-increasing protein (BPI) on LPS-dependent activation of mouse thioglycolate-elicited peritoneal macrophages in vitro, in comparison with human PBM
Publikováno v:
Methods in molecular medicine. 36
Endotoxins have been recognized for decades as important structural components of the outer cell wall/cell membrane complex of Gram-negative microorganisms. These chemically heterogeneous macromolecular structures were recognized very early on to con
Publikováno v:
The Journal of Immunology. 151:2742-2752
A mutant cell line (J7.DEF.3) derived from murine macrophage-like J774.1 cells, was isolated on the basis of defective specific 125I-labeled LPS-binding in the presence of serum. Although J7.DEF.3 cells still respond to LPS in inducing TNF-alpha rele
Publikováno v:
The Journal of Immunology. 151:389-396
Adenosine (ADO) and its structurally related analogues are known to regulate the activities of immune and inflammatory cells, including a number of key functions of mononuclear phagocytes. In this study ADO and the synthetic ADO analogue MDL201112 in
Autor:
X Zhang, D C Morrison
Publikováno v:
The Journal of Immunology. 150:1011-1018
It has been established that LPS, the major constituent of the outer membrane of gram negative bacteria, stimulates macrophages to produce numerous inflammatory mediators, including TNF-alpha and nitric oxide (NO). Both TNF-alpha and NO are important
Autor:
D. C. Morrison, Mei-Guey Lei
Publikováno v:
Journal of Biological Chemistry. 268:1488-1493
Using radioiodinated, photoactivable, reducible cross-linker conjugated bacterial endotoxic lipopolysaccharide (125I-ASD-LPS), we have demonstrated that LPS selectively binds to the S2 subunit of pertussis toxin (PT). Since LPS also interacts with th
Publikováno v:
The Journal of Immunology. 147:1925-1932
In previously published studies, we employed a photoreactive radioiodinated derivative of LPS from Escherichia coli 0111:B4 to identify and characterize a membrane-localized specific LPS binding protein of approximately 80-kDa molecular mass. Our mor
Publikováno v:
Proceedings of the Nutrition Society. 50:37-43
Publikováno v:
The Journal of Immunology. 146:723-729
Lactoferrin (LF) has been implicated in a number of functions including the negative regulation of myelopoiesis in vitro and in vivo, an effect mediated by suppression of cytokine release from monocytes/macrophages. This suppression is abrogated by b
Publikováno v:
The Journal of Immunology. 145:1505-1511
We have investigated the relative immunostimulatory activities of S-chemotype LPS and R-chemotype LPS preparations on C3H/HeJ peritoneal macrophages in vitro. As assessed by either secretion of TNF-alpha or IL-1, some of the R-chemotype LPS manifest