Zobrazeno 1 - 7
of 7
pro vyhledávání: '"D. C. Goodwin"'
Publikováno v:
The Journal of biological chemistry. 275(9)
The two isoforms of cyclooxygenase, COX-1 and COX-2, are acetylated by aspirin at Ser-530 and Ser-516, respectively, in the cyclooxygenase active site. Acetylated COX-2 is essentially a lipoxygenase, making 15-(R)-hydroxyeicosatetraenoic acid (15-HET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a16d00677dd3ac38f40b585f20180f2
https://pubmed.ncbi.nlm.nih.gov/10692466
https://pubmed.ncbi.nlm.nih.gov/10692466
Publikováno v:
The Journal of biological chemistry. 274(33)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eca5ab94b3582705a5b1e1a19465d0d1
https://pubmed.ncbi.nlm.nih.gov/10438452
https://pubmed.ncbi.nlm.nih.gov/10438452
Publikováno v:
The Journal of biological chemistry. 273(15)
Tyrosyl radicals have been detected during turnover of prostaglandin endoperoxide H synthase (PGHS), and they are speculated to participate in cyclooxygenase catalysis. Spectroscopic approaches to elucidate the identity of the radicals have not been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8712c8e004af27150353482606af1e0
https://pubmed.ncbi.nlm.nih.gov/9535872
https://pubmed.ncbi.nlm.nih.gov/9535872
Publikováno v:
Biochemical Journal. 191:729-742
Two novel antibiotics were isolated, designated compounds 1QN and 2QN respectively, having quinoline rings in place of one or both of the quinoxaline chromophores of echinomycin. Each removes and reverses the supercoiling of closed circular duplex DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e1f273e521a7517db3f2eebdd3a6c6
https://doi.org/10.1042/bj1910729
https://doi.org/10.1042/bj1910729
Autor:
J. Brahms, Arumugam Mahendrasingam, N. J. Rhodes, W. J. Pigram, D. C. Goodwin, J. Vergne, Watson Fuller, Colin Nave
Publikováno v:
Nature. 301:535-537
The synthetic polynucleotide poly[d(AT)].poly[d(AT)] is of interest in studies of the relationship between nucleic acid structure and function. In particular, A + T-rich regions in DNA double helices have been invoked as centres for controlling the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccc4e6f21a6f04a27d1cdcb80df7f47
https://doi.org/10.1038/301535a0
https://doi.org/10.1038/301535a0
Publikováno v:
Biochemistry. 18(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6639cca660d06c212724f4c3e77f43
https://pubmed.ncbi.nlm.nih.gov/435464
https://pubmed.ncbi.nlm.nih.gov/435464
Publikováno v:
Biochemistry. 18:4263-4263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc786e21574be83b517fcfaae25c5374
https://doi.org/10.1021/bi00586a616
https://doi.org/10.1021/bi00586a616